@andresthedietitian's NAD+ injection claims, fact-checked
Quick answer
NAD+ is a coenzyme involved in cellular energy metabolism that declines approximately 50% between ages 20-80. While NAD+ precursor supplements can raise blood levels, human studies show no consistent improvements in energy, performance, or aging markers. NAD+ injections lack substantial human safety and efficacy data.
Our take · Written by FormBlends editorial team · Reviewed by FormBlends Medical Team· This is not a transcript. It is our independent review of the video above.
A dietitian with 305K views is injecting NAD+ for energy and anti-aging. He's right that NAD+ levels decline with age, but wrong about what that means for you.
What does this video actually claim?
Andres says NAD+ is essential for energy production, cell repair, and slowing aging. He claims declining NAD+ levels cause fatigue and poor recovery as we age.
He's testing NAD+ injections from IVYRX Health to see if they work better than other options. The video positions this as science-based experimentation, not a celebrity trend.
He stops mid-sentence when comparing injections to other NAD+ supplements, leaving viewers hanging on the comparison.
Does the science support NAD+ injections?
The human data is thin. Most NAD+ research happens in mice or test tubes, not people walking around complaining about low energy.
A 2022 study by Pencina et al. in Nature Communications found oral NAD+ precursors increased blood NAD+ levels in healthy adults. But higher blood levels didn't translate to measurable improvements in energy or physical performance.
The anti-aging claims rest on even shakier ground. Rajman et al. reviewed NAD+ research in 2018 and found promising cellular studies but acknowledged the leap to human longevity benefits remains largely theoretical.
NAD+ injections specifically have almost no published human trials. You're essentially paying to be a test subject.
What did Andres get wrong?
He treats NAD+ decline like a deficiency disease that needs correction. That's not how aging works.
Yes, NAD+ levels drop about 50% between ages 20 and 80, according to Verdin's 2015 review in Science. But correlation isn't causation. Lots of things decline with age without causing the problems we blame on them.
The bigger issue: he's promoting injections without mentioning they're largely untested in humans. A responsible dietitian would acknowledge that gap instead of casually injecting himself on social media.
His "testing this firsthand" approach sounds scientific but it's just an expensive placebo trial with one participant.
What should you actually know about NAD+?
NAD+ is real and important for cellular energy production. The decline with aging is well-documented.
But jumping from "levels decline" to "injections will help" skips the most important question: do higher NAD+ levels actually improve how you feel or function?
The evidence suggests probably not. Exercise, sleep, and basic nutrition do more for energy and recovery than any NAD+ supplement we've tested so far.
If you're dealing with fatigue or poor recovery, start with thyroid function, vitamin D levels, and sleep quality. Those have actual treatment protocols with proven outcomes.
Save your money until we have real human data on NAD+ injections.
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For @andresthedietitian's NAD+ injection claims, fact-checked, FormBlends checks the page topic against primary trials, systematic reviews, guidelines, and current PubMed-indexed literature where available. These citations are context, not medical advice, proof of eligibility, or a claim that every study applies to every patient.
NAD+ metabolism and its roles in cellular processes during ageing
Core review for NAD+ decline, mitochondrial function, DNA repair, and aging biology.
PubMed
Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women
Human NMN source for metabolic claims while keeping population limits clear.
PubMed
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NAD+ is a coenzyme involved in cellular energy metabolism that declines approximately 50% between ages 20-80.
FormBlends verdict
NAD+ is a coenzyme involved in cellular energy metabolism that declines approximately 50% between ages 20-80. While NAD+ precursor supplements can raise blood levels, human studies show no consistent improvements in energy, performance, or aging markers. NAD+ injections lack substantial human safety and efficacy data.
Patient-safe next step
Compare the claim with the NAD+ Peptide Complex guide, safety notes, access rules, and a licensed-provider review.
What to do with this video
Use the clip as a claim to verify, not a treatment plan
What it helps with
- NAD+ is a coenzyme involved in cellular energy metabolism that declines approximately 50% between ages 20-80. While NAD+ precursor supplements can raise blood levels, human studies show no consistent improvements in energy, performance, or aging markers. NAD+ injections lack substantial human safety and efficacy data.
- NAD+ levels decline about 50% between ages 20-80, but higher levels don't necessarily improve energy or performance
- Human studies of NAD+ precursors show increased blood levels but no consistent functional benefits
What it may miss
- It may not cover eligibility, contraindications, medication interactions, lab history, or dose escalation.
- NAD+ Peptide Complex decisions still need source quality, legal access, and provider oversight checks.
- Social video captions rarely show the full evidence base behind a claim.
Best next step
Compare the claim against the NAD+ Peptide Complex guide, cost path, safety notes, and provider review before acting.
Review NAD+ Peptide ComplexWhat You'll Learn
- NAD+ levels decline about 50% between ages 20-80, but higher levels don't necessarily improve energy or performance
- Human studies of NAD+ precursors show increased blood levels but no consistent functional benefits
- NAD+ injections have almost no published human safety or efficacy data
- Self-experimentation by influencers isn't scientific evidence of effectiveness
- Exercise, sleep optimization, and addressing nutrient deficiencies have stronger evidence for energy and recovery
- Fatigue and poor recovery have many treatable medical causes that should be evaluated first
- The anti-aging claims for NAD+ are largely based on animal studies that don't translate to humans
Interested in GLP-1 or peptide therapy?
Get matched with licensed-provider review to help decide if it is right for you.
About the Creator
Andres | Fat Loss Dietitian · TikTok creator
305.7K views on this video
I started on NAD+ injections 3 days ago... And no, it’s not some celebrity longevity hack or a magic bullet. I’ve been diving deep into the science behind NAD+ — a coenzyme your body needs to create
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Our written guides go deeper with dosing details, comparison tables, and medical-team reviewed protocols.
Not medical advice. This video was made by Andres | Fat Loss Dietitian, not by FormBlends. Our write-up above is an editorial review, not a medical recommendation. Talk to your doctor before making any decisions about medications or treatments.