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Auto-generated transcript of @daphnunez's video. Quoted here for educational fact-check commentary; original creator retains all rights to the video content.
- 0:00August was a bit of a bender for me because it was my birthday and I was just doing like so many
- 0:03birthday celebrations with my friends and you know drinking more than I probably should but I
- 0:08had to get blood work right after my birthday weekend. I flew back from New York. I was nervous. Like
- 0:14I was nervous. My liver enzymes like it was all going to be complete mess and let me tell you
- 0:19out of doctor's deployment and we went over all my labs. My blood work was the best it's ever been
- 0:25and she was like what are you doing different? The enzymes like the biomarkers that show like
- 0:29your liver health. My numbers were insanely improved. Like they were great and she was like
- 0:35what are you doing different? Like diet, lifestyle, my head, my head, I'm like I've had pizza and
- 0:40bagels and drinking and no it's been the opposite. I was like girl, NAD injections every single day
- 0:47and glutathione. Those two things are going to help so much with your liver. I wish that everyone could
- 0:54do NAD injections. Like I wish everyone could afford it. I mean one day it will it is getting like
- 1:00more and more accessible before it was just like celebrities being able to do it. How your body is
- 1:05actually functioning yourselves it is going to help you feel better for longer and just have a better
- 1:12life. So anyways I just like wanted to share that. I know I promote NAD so much and glutathione but
- 1:20at home injections are the way to go. It is actually cheaper to do at home. It's not scary to
- 1:26inject yourself and absolutely promise if you want more information it's in my bio. I go through
- 1:32IV. Yeah it's really great. If you guys have any questions just drop it in the comments and I am
- 1:38here to help.
NAD+ and liver health: what the evidence actually supports
Quick answer
The creator attributes improved liver enzyme results (likely ALT, AST) to daily subcutaneous NAD+ injections and glutathione taken during a period of heavy alcohol consumption. While NAD+ depletion during alcohol metabolism is a documented physiological process, no controlled human trials have established that subcutaneous NAD+ injections normalize liver enzymes in this context. Liver enzyme fluctuation after reduced alcohol intake and improved hydration alone is a plausible confounding factor that cannot be ruled out from a single anecdotal lab result.
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This page currently connects to 8 source-backed evidence items through visible references or structured citation data.
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For NAD+ and liver health: what the evidence actually supports, FormBlends checks the page topic against primary trials, systematic reviews, guidelines, and current PubMed-indexed literature where available. These citations are context, not medical advice, proof of eligibility, or a claim that every study applies to every patient.
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What this exact clip is really saying
This FormBlends review is specific to "NAD+ and liver health: what the evidence actually supports" from Daphne. We read the clip as a Peptide social video fact-checks claim about NAD+ Peptide Complex, then separate the useful signal from what a short social video cannot prove. The page-specific claim focus is: The creator attributes improved liver enzyme results (likely ALT, AST) to daily subcutaneous NAD+ injections and glutathione taken during a period of heavy alcohol consumption.
The reason this review is not generic is the source wording and the canonical claim label "peptides nad is like your liver s best friend when you re living fast." In this clip, the useful excerpt is: "August was a bit of a bender for me because it was my birthday and I was just doing like so many birthday celebrations with my friends and you know drinking more than I probably should but I had to get blood work right after my birthday..." That wording changes the review because it points to NAD+ Peptide Complex safety, access, evidence, and fit, not a one-size-fits-all protocol.
The source trail for this page is checked against NAD+ metabolism and its roles in cellular processes during ageing (2021), Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women (2021), and Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults (2018), plus the creator's own wording. NAD+ Peptide Complex still needs an eligibility review, medication-interaction screen, access check, and quality-control review before anyone treats a social clip as medical advice.
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Claim being checked
The creator attributes improved liver enzyme results (likely ALT, AST) to daily subcutaneous NAD+ injections and glutathione taken during a period of heavy alcohol consumption.
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Compare the claim with the NAD+ Peptide Complex guide, safety notes, access rules, and a licensed-provider review.
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Use the clip as a claim to verify, not a treatment plan
What it helps with
- The creator attributes improved liver enzyme results (likely ALT, AST) to daily subcutaneous NAD+ injections and glutathione taken during a period of heavy alcohol consumption. While NAD+ depletion during alcohol metabolism is a documented physiological process, no controlled human trials have established that subcutaneous NAD+ injections normalize liver enzymes in this context. Liver enzyme fluctuation after reduced alcohol intake and improved hydration alone is a plausible confounding factor that cannot be ruled out from a single anecdotal lab result.
- NAD+ depletion during alcohol metabolism is real biochemistry, but no human RCT has shown subcutaneous NAD+ injections normalize liver enzymes after drinking.
- Liver enzymes (ALT, AST) commonly normalize within days of reduced alcohol intake and improved hydration, making attribution to any supplement extremely difficult without controlled conditions.
What it may miss
- It may not cover eligibility, contraindications, medication interactions, lab history, or dose escalation.
- NAD+ Peptide Complex decisions still need source quality, legal access, and provider oversight checks.
- Social video captions rarely show the full evidence base behind a claim.
Best next step
Compare the claim against the NAD+ Peptide Complex guide, cost path, safety notes, and provider review before acting.
Review NAD+ Peptide ComplexWhat You'll Learn
- NAD+ depletion during alcohol metabolism is real biochemistry, but no human RCT has shown subcutaneous NAD+ injections normalize liver enzymes after drinking.
- Liver enzymes (ALT, AST) commonly normalize within days of reduced alcohol intake and improved hydration, making attribution to any supplement extremely difficult without controlled conditions.
- A 2022 review by Mehmel et al. in Nutrients found modest metabolic benefits from NAD+ precursor supplementation in humans but did not identify liver enzyme normalization after alcohol use as a demonstrated outcome.
- Glutathione has more human trial support for liver health (Nakamura et al., 2019, European Journal of Gastroenterology and Hepatology showed reduced liver fat in NAFLD), but subcutaneous bioavailability differs significantly from IV delivery.
- The FDA has flagged concerns about compounded NAD+ products sold for injection outside of supervised clinical settings. At-home injection without medical oversight carries infection and dosing risks.
- One person's blood work is not evidence. Anecdote plus a plausible mechanism is not the same as proven efficacy, and presenting it to 18,000 viewers as a recommendation crosses a line.
- If your liver enzymes are elevated after heavy drinking, that is a reason to see a clinician, not to order injections from a TikTok bio link.
Our take · Written by FormBlends editorial team · Reviewed by FormBlends Medical Team · This is not a transcript. It is our independent review of the video above.
What did @daphnunez actually say?
The short version: she spent August drinking heavily for her birthday, expected her liver labs to be a mess, and instead got results her doctor called the best she'd ever seen. Her explanation? "NAD injections every single day and glutathione." She's promoting at-home self-injection of both and pointing viewers to her bio for more information.
To be fair to her, she didn't claim NAD+ cures liver disease or fixes alcoholism. She shared a personal lab result and credited a supplement protocol. That's a softer claim than a lot of what circulates on wellness TikTok. But "softer" doesn't mean accurate, and one person's blood work isn't a clinical trial. The leap from "my enzymes looked good" to "NAD injections are going to help so much with your liver" for everyone is a significant one that deserves scrutiny.
Does the science back this up?
There's real biology here, but the human evidence is thin and mostly comes from IV NAD+ in clinical settings, not daily at-home subcutaneous injections. NAD+ is genuinely involved in hepatic metabolism. The problem is the gap between mechanism and proven outcome is wide.
In animal models, NAD+ precursor supplementation has shown protective effects against alcohol-induced liver injury. A 2021 study by Radenkovic et al. in Cell Metabolism reviewed NAD+ metabolism and noted its role in mitochondrial function and cellular repair, but explicitly flagged the lack of robust human RCTs. A 2022 study by Mehmel et al. in Nutrients reviewed NAD+ supplementation broadly and found modest benefits in some metabolic markers in humans, but liver enzyme normalization after alcohol consumption was not a demonstrated outcome. Glutathione has somewhat stronger liver-support data, particularly in non-alcoholic fatty liver disease (NODA et al., 2022, European Journal of Gastroenterology and Hepatology), but again, IV glutathione and subcutaneous self-injection are not the same delivery system with the same bioavailability.
What did they get wrong (or right)?
Let's give credit where it's due: NAD+ is not a made-up wellness gimmick. It is a coenzyme that plays a documented role in DNA repair, mitochondrial function, and alcohol metabolism via alcohol dehydrogenase pathways. The idea that NAD+ depletion occurs during heavy alcohol use is biochemically sound. Alcohol metabolism consumes NAD+ and shifts the NAD+/NADH ratio, which is a real phenomenon described in standard hepatology literature.
What she got wrong, or at least badly oversimplified: one set of good labs after a drinking month doesn't prove causation. Liver enzymes fluctuate. They can look fine after a week of rest, hydration, and even just stopping drinking, regardless of any supplementation. She also conflates clinical IV NAD+ protocols (used in addiction medicine under supervision) with daily at-home subcutaneous injections, which have meaningfully different absorption profiles. Telling viewers "I wish everyone could do NAD injections" and directing them to her bio to purchase is promotional, not informational.
What should you actually know?
If your liver enzymes are elevated, that is a clinical finding that requires a clinician, not a supplement stack from a TikTok bio. Alcohol-related liver enzyme elevation, particularly in ALT and AST, reflects hepatocyte stress. While NAD+ precursors like NMN and NR have been studied for metabolic support, no peer-reviewed trial has established that subcutaneous NAD+ injections normalize liver enzymes after alcohol consumption in otherwise healthy adults.
Glutathione does have more substantive human data for liver support. A randomized trial by Nakamura et al. (2019, European Journal of Gastroenterology and Hepatology) found oral glutathione reduced liver fat in NAFLD patients over four weeks. But subcutaneous glutathione absorption is debated, and "detox" framing around glutathione often overstates what the evidence shows.
- At-home injection of any compound carries real infection and dosing risks, particularly without medical supervision.
- Liver enzymes can normalize on their own with rest and abstinence. Attribution is genuinely hard without a controlled condition.
- NAD+ injections are not FDA-approved for liver health. Any compound sold for this purpose is operating in a regulatory gray area.
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About the Creator
Daphne · TikTok creator
18.4K views on this video
NAD+ is like your liver’s best friend. 💛 When you’re living fast — late nights, deadlines, maybe a cocktail (or three) 🍸 — your liver works overtime to detox and repair. Boosting NAD+ helps your liver flush toxins, repair cells, and keep energy production high so you don’t crash. ✨ Think of it as extra insurance for your body’s main filter. I only trust and use @IVY. More info in my bio on how to get prescribed #liverhealth #liver #detox #peptide
Frequently asked questions
Quick answers based on this video and our medical team review.
What does the video say about nad+ depletion during alcohol metabolism?
NAD+ depletion during alcohol metabolism is real biochemistry, but no human RCT has shown subcutaneous NAD+ injections normalize liver enzymes after drinking.
What does the video say about liver enzymes (alt, ast) commonly normalize within days of reduced?
Liver enzymes (ALT, AST) commonly normalize within days of reduced alcohol intake and improved hydration, making attribution to any supplement extremely difficult without controlled conditions.
What does the video say about a 2022 review by mehmel et al. in nutrients found?
A 2022 review by Mehmel et al. in Nutrients found modest metabolic benefits from NAD+ precursor supplementation in humans but did not identify liver enzyme normalization after alcohol use as a demonstrated outcome.
What does the video say about glutathione has more human trial support for liver health (nakamura?
Glutathione has more human trial support for liver health (Nakamura et al., 2019, European Journal of Gastroenterology and Hepatology showed reduced liver fat in NAFLD), but subcutaneous bioavailability differs significantly from IV delivery.
What does the video say about the fda has flagged concerns about compounded nad+ products sold?
The FDA has flagged concerns about compounded NAD+ products sold for injection outside of supervised clinical settings. At-home injection without medical oversight carries infection and dosing risks.
What does the video say about one person's blood work?
One person's blood work is not evidence. Anecdote plus a plausible mechanism is not the same as proven efficacy, and presenting it to 18,000 viewers as a recommendation crosses a line.
Sources & references
Citations extracted from our medical team's review. Click any citation to search PubMed.
Read More on This Topic
Our written guides go deeper with dosing details, comparison tables, and medical-team reviewed protocols.
Not medical advice. This video was made by Daphne, not by FormBlends. Our write-up above is an editorial review, not a medical recommendation. Talk to your doctor before making any decisions about medications or treatments.