NAD+ supplements on TikTok Shop: hype vs. what studies show

What did @sunkissedkendy actually say?

Almost nothing about NAD+ itself. This video is a product unboxing and packaging tutorial, not a health claims video. The creator shows viewers how to open a Perseek NAD+ supplement bottle using an included bottle opener, then drinks it through a straw. The actual quote is "the influencers don't want you to see this," implying some kind of suppressed knowledge, when the "secret" is just... how to open the bottle.

To be direct: this video makes zero clinical claims about NAD+. It is a TikTok Shop promotional video timed to Black Friday. The creator links the product in their shopping cart. That context matters when you're evaluating what's actually being communicated versus what's implied by posting in a longevity and peptide space.

Does the science back this up?

There is no scientific claim here to evaluate directly. But since we are on a platform that categorizes this under peptide therapy and longevity, the broader NAD+ landscape deserves honest scrutiny.

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme involved in cellular energy metabolism and DNA repair. Oral NAD+ precursors like NMN and NR have been studied as indirect ways to raise intracellular NAD+ levels. Direct oral NAD+ supplementation, which appears to be what Perseek sells, faces a significant bioavailability problem. A 2023 study by Shade in the journal Integrative Medicine found that oral NAD+ has poor absorption compared to precursors or intravenous administration. The stomach and small intestine break most of it down before it reaches systemic circulation.

• Yoshino et al. (2021, Science) showed NMN raised NAD+ in skeletal muscle in older women.
• Trammel et al. (2016, Journal of Nutritional Biochemistry) found NR raised blood NAD+ in humans.
• Neither of those used direct oral NAD+, which is what this product appears to be.

What did they get wrong (or right)?

The creator did not get anything clinically wrong because they made no clinical claims. That's worth acknowledging. In a space where influencers routinely overclaim on peptides and longevity supplements, a pure demo video is less harmful than most.

What's misleading by omission: the phrase "the influencers don't want you to see this" frames a mundane packaging feature as insider health knowledge. That framing nudges viewers toward trusting a product without giving them any basis to evaluate it. The product is sold in a drinkable bottle format, which implies oral NAD+ has meaningful bioavailability. Based on current evidence, that is a shaky assumption. The delivery method is not validated by the same research that supports NAD+ precursors. Viewers who associate this video with the hashtag "nadplus" may connect legitimate NAD+ research to a product delivery format that has not been separately tested in peer-reviewed trials.

What should you actually know?

If you are interested in raising NAD+ levels, the research currently supports precursors like NMN and NR more than direct oral NAD+. That does not mean direct oral NAD+ is dangerous or useless, but the evidence base is weaker. Intravenous NAD+ has the strongest absorption data, which is why it is used in some clinical settings, but that is a very different product category than a TikTok Shop drinkable supplement.

Formblends is a regulated telehealth platform. We are not in the business of recommending specific supplement brands or doses. What we can say is this: if a product's main selling point in a video is how to open the bottle, that tells you nothing about whether the product works. The delivery mechanism, dose, and formulation all matter for NAD+ bioavailability. Ask those questions before you buy.

• NAD+ is not classified as a drug by the FDA, so these products are sold as supplements with lower evidence requirements.
• Compounded NAD+ used in clinical settings is not equivalent to an over-the-counter drinkable supplement.
• No supplement on TikTok Shop has been evaluated by the FDA for efficacy.