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GLP-1 adoption in South Dakota

South Dakota has an estimated 44,079 GLP-1 users across 66 counties. Average estimated adoption is 0.7 percentage points below the national rate of 5.7%.

Last reviewed |Reviewed by the FormBlends Editorial Standards Team

5%

Est. adoption rate

44,079

Est. users

36.4%

Avg adult obesity

890,342

Adult population

State facts for search and AI answers

What makes the South Dakota GLP-1 page useful

This page ties the statewide answer to county-level demand, coverage context, and practical access checks. The goal is to help readers move from a broad state estimate to the local county or provider question that actually matters.

State signal

South Dakota: 66 counties, 44,079 estimated GLP-1 users

State pages summarize the county-level demand model before readers drill into local pages.

Model inputs

Average adoption 5%; average adult obesity 36.4%

The model uses CDC PLACES obesity prevalence, Census population, and KFF national GLP-1 utilization.

Coverage context

South Dakota Medicaid does not cover GLP-1s for obesity. Coverage for T2D, cardiovascular disease, and sleep apnea indications is still available. According to KFF (2026-01-16), federal Medicaid rules require GLP-1 coverage for type 2 diabetes, cardiovascular disease, and sleep apnea indications. Obesity coverage is optional and varies by state.

Coverage policy can make real access higher or lower than projected local demand.

How to use this page

Find counties with the strongest demand signal, then verify coverage, provider access, and pharmacy source before starting care.

This is a local planning page, not a prescription recommendation.

Counties ranked by estimated adoption

Adoption strip: each bar is one county, tallest = highest estimated rate
County adoption strip. Tallest bar = highest projected adoption in South Dakota.
Ranked counties in South Dakota by estimated GLP-1 adoption.
RankCountyPopulationObesity %Est. adoptionEst. users
1Todd9,35350.2%6.8%639
2Buffalo1,85949.0%6.7%124
3Oglala Lakota13,69547.7%6.5%889
4Ziebach2,45547.6%6.5%159
5Mellette1,98946.2%6.3%125
6Corson3,90644.3%6.0%236
7Dewey5,27543.9%6.0%315
8Roberts10,24243.5%5.9%606
9Bennett3,39143.1%5.9%199
10Jackson2,83841.8%5.7%161
11Charles Mix9,30241.0%5.6%519
12Lyman3,71940.7%5.5%206
13Clay14,95339.8%5.4%810
14Brookings34,63139.5%5.4%1,863
15Yankton23,31138.8%5.3%1,231
16Davison19,96638.6%5.3%1,048
17Brule5,24738.5%5.2%275
18Tripp5,60737.8%5.2%289
19Fall River7,07937.6%5.1%362
20Bon Homme7,01837.5%5.1%358
21Grant7,53337.5%5.1%384
22Minnehaha197,74237.1%5.0%9,986
23Faulk2,14036.8%5.0%107
24Aurora2,59036.7%5.0%130
25Gregory3,98336.6%5.0%198
26Codington28,40236.2%4.9%1,400
27Miner2,31236.2%4.9%114
28Spink6,35536.2%4.9%313
29Perkins2,97036.1%4.9%146
30McPherson2,25136.0%4.9%110
31Sanborn2,37336.0%4.9%116
32Douglas2,82335.9%4.9%138
33Jerauld1,83635.9%4.9%90
34McCook5,71435.9%4.9%279
35Butte10,36935.8%4.9%505
36Hanson3,44335.8%4.9%168
37Hyde1,31935.8%4.9%64
38Kingsbury5,17235.8%4.9%252
39Marshall4,36335.7%4.9%212
40Brown38,27835.5%4.8%1,849
41Jones1,00635.5%4.8%49
42Beadle19,08935.4%4.8%920
43Potter2,58735.3%4.8%124
44Day5,48535.2%4.8%263
45Stanley2,97935.2%4.8%143
46Hamlin6,19635.1%4.8%296
47Harding1,17635.1%4.8%56
48Sully1,31835.0%4.8%63
49Lincoln65,80134.8%4.7%3,119
50Walworth5,31734.7%4.7%251
51Hutchinson7,40134.6%4.7%349
52Haakon1,75534.4%4.7%82
53Hand3,07534.4%4.7%144
54Clark3,83734.3%4.7%179
55Hughes17,81233.9%4.6%821
56Turner8,68733.9%4.6%400
57Campbell1,53433.7%4.6%70
58Edmunds4,01433.7%4.6%184
59Pennington110,38633.7%4.6%5,067
60Custer8,51533.6%4.6%389
61Moody6,34633.6%4.6%290
62Deuel4,29833.4%4.5%196
63Lake11,20733.2%4.5%507
64Lawrence26,04733.1%4.5%1,175
65Union16,70031.0%4.2%705
66Meade29,97030.9%4.2%1,262

How South Dakota fits the national picture

The KFF 2024 poll pegged national adult GLP-1 use at 5.7%. Applied to South Dakota's obesity profile, the model projects 5% of adults are on a GLP-1 medication. That matches the county-level obesity data from CDC PLACES (2023) more than any measured prescription count; the state's real share could be higher in urban areas with broad commercial coverage, or lower in rural regions where prescriber access is limited.

Compounded semaglutide and tirzepatide complicate the picture. After the FDA shortage resolution in late 2024 and early 2025, compounded supply dropped sharply. Brand-name utilization rose. The county numbers here don't separate brand vs. compounded, because no public dataset does yet.

Decision path

How should I use the South Dakota GLP-1 map?

This state view is a demand and access signal, not a prescription recommendation. Use it to understand where GLP-1 need may be concentrated, then pressure-test provider availability, insurance rules, and pharmacy quality before starting care.

State
South Dakota
Counties
66
Est. users
44,079
Avg adoption
5%

Step 1

Find county context

County estimates help separate broad statewide demand from the local access picture a patient actually experiences.

Review counties

Step 2

Check coverage and price

South Dakota access depends on payer policy, prior authorization, cash-pay pricing, and whether local clinicians can support follow-up.

Check coverage path

Step 3

Decide on care route

If local access is thin or pricing is unclear, a supervised telehealth assessment can clarify eligibility and next steps.

Compare provider options
Start provider review in South DakotaReview pharmacy oversight

Evidence standard

How this page was source-checked

Editorial policy

FormBlends does not claim an individual clinician byline unless a named reviewer is available. For this page, the editorial team checks medical and regulatory claims against primary sources, clinical trials, public datasets, and regulator guidance.

CDC PLACES

Dataset

Used for county-level obesity inputs in local GLP-1 adoption estimates.

KFF GLP-1 utilization polling

Dataset

Used as the national anchor for estimated GLP-1 adoption.

STEP 1 semaglutide obesity trial

Trial

Primary trial source for semaglutide 2.4 mg weight-loss expectations and side effects.

Frequently asked questions

How is GLP-1 adoption calculated for South Dakota counties?
We multiply each county's CDC PLACES 2023 adult obesity prevalence by a scaling factor k = 0.1361, which comes from the KFF 2024 figure of 5.7% national GLP-1 adoption divided by the 41.9% national adult obesity rate. That gives an estimated per-county adoption %. Multiply by Census ACS 5-year 2022 county population to get projected users. South Dakota shows 5% state-average adoption under this model.
Why is South Dakota's number 0.7 percentage points below the national average?
Adult obesity prevalence in South Dakota averages 36.4% (CDC BRFSS 2024, state-level). The national average is 41.9%. The model links adoption linearly to obesity, so states above the national obesity rate come out above the national adoption estimate, and vice versa. Real variation also depends on commercial insurance coverage and Medicaid GLP-1 policy, both of which differ significantly by state.
Do Medicaid enrollees in South Dakota get GLP-1 coverage?
South Dakota Medicaid does not cover GLP-1s for obesity. Coverage for T2D, cardiovascular disease, and sleep apnea indications is still available. According to KFF (2026-01-16), federal Medicaid rules require GLP-1 coverage for type 2 diabetes, cardiovascular disease, and sleep apnea indications. Obesity coverage is optional and varies by state.
What studies back up GLP-1 weight loss expectations?
The STEP 1 trial (Wilding et al., NEJM, 2021) enrolled 1,961 adults on 2.4mg weekly semaglutide over 68 weeks and saw mean body weight change of negative 14.9% vs negative 2.4% on placebo. SURMOUNT-1 (Jastreboff et al., NEJM, 2022) tested tirzepatide in 2,539 adults over 72 weeks and saw negative 20.9% at 15mg weekly. Both were randomized, double-blind, and placebo-controlled.
How often does the South Dakota county data refresh?
CDC PLACES releases annually in late summer. Census ACS 5-year estimates release every December. KFF reruns its GLP-1 utilization poll roughly twice a year. We re-run the full county model whenever any of those update, and the last-reviewed date at the top of every page reflects the most recent refresh.

Sources

Related reading

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Original tools and data

Use the FormBlends research stack

These assets are built to be useful beyond a single article: shareable data pages, calculators, provider comparisons, and safety checks that give Google and readers something original to crawl.

2026 GLP-1 Telehealth Report

105 providers scored on price, safety, compliance, and patient experience.

Compounded GLP-1 ZIP Lookup

State pharmacy-board posture and telehealth access for US ZIP codes.

America on GLP-1 Map

County-level adoption estimates using CDC, Census, and KFF inputs.

Looking for GLP-1 care in South Dakota?

FormBlends ships compounded semaglutide and tirzepatide to South Dakota with licensed telehealth consultations.

Start your assessment

Estimated adoption figures are modeled projections from public data, not measured prescription counts. This page is general information, not medical advice. Individual results vary. Talk to a licensed healthcare provider before starting any medication.