What did @thewellnesspharm actually say?
A self-identified pharmacist walked through a nightly routine claiming it targets "younger looking skin, better sleep, and low cortisol." The routine included glycolic acid, a growth factor serum with "NAD plus" and something linked to "mononuclein," an antioxidant mist, magnesium drink, liposomal collagen, breathwork, red light therapy, journaling, a mouth tape for "more nitric oxide," and a white noise machine placed in another room.
She claimed oral bacteria "can actually enter your bloodstream overnight" and increase cardiovascular inflammation. She said liposomal collagen is best taken at night because "that's actually when your gut can repair." She credited the white noise machine with better sleep than "melatonin or anything from the pharmacy." Several of these claims are either supported by decent evidence, loosely supported, or plainly wrong.
Does the science back this up?
Some of it, yes. The oral-cardiovascular link is real. The magnesium-sleep connection has solid backing. The red light and journaling claims are reasonable. But the mouth tape claim about nitric oxide is backwards, and the "liposomal collagen at night for gut repair" framing mixes up two separate things with thin evidence connecting them.
The oral-cardiovascular inflammation link is well-established. Periodontitis is independently associated with cardiovascular disease risk, and oral pathogens like Porphyromonas gingivalis have been detected in atherosclerotic plaques (Tonetti et al., 2013, Journal of Clinical Periodontology). Magnesium's role in sleep is supported by multiple trials. Abbasi et al. (2012, Journal of Research in Medical Sciences) found magnesium supplementation improved sleep quality in older adults. Red light therapy, specifically 630-850nm wavelengths, has demonstrated some skin collagen stimulation in small trials (Barolet et al., 2009, Journal of Investigative Dermatology), though 30 minutes of daily use is on the higher end of studied protocols.
What did they get wrong (or right)?
The mouth tape claim is the clearest error. She says it helps produce "more nitric oxide for better circulation," presumably referencing nasal breathing. The nitric oxide-nasal breathing connection is real, but mouth tape does not generate nitric oxide. It redirects breathing. The nitric oxide is produced in nasal sinuses during nasal breathing itself (Lundberg et al., 1996, Acta Physiologica Scandinavica). Conflating the tape with the biochemistry is sloppy.
The "NAD plus serum" and "mononuclein" references are garbled. NAD+ precursors like NMN and NR have oral bioavailability data, but topical NAD+ delivery to skin cells is not well-studied. It is not clear what "mononuclein" refers to, possibly NMN mispronounced, but the claim that it "amounts to growth of new healthy skin cells" is unsupported by published topical trials.
She gets credit for the journaling recommendation. Cognitive shuffling and expressive writing before bed do reduce pre-sleep cognitive arousal. Harvey (2001, Behaviour Research and Therapy) linked worry suppression strategies to improved sleep onset. The white noise claim also has support. Stanchina et al. (2005, Sleep Medicine) found continuous white noise reduced sleep disruptions in an ICU environment.
What should you actually know?
This routine is not dangerous, but it is being sold as more scientifically precise than it is. Some elements, magnesium, red light, oral hygiene, journaling, have credible evidence behind them. Others, like topical NAD+ serums and liposomal collagen timed to "gut repair cycles," are marketing claims dressed in clinical language.
The bigger issue is the framing. Calling this "biohacking" gives the impression of a rigorously tested system. It is not. It is a combination of legitimate wellness habits, some plausible but unproven interventions, and at least one claim (the mouth tape-nitric oxide mechanism) that gets the science wrong. If you are a FormBlends patient considering any peptide or compounded product referenced adjacent to this content, that requires a clinical consultation, not a TikTok routine. Growth factors, GHK-Cu, and NAD+ injectables carry real regulatory and safety considerations that a 60-second video cannot address.
- Magnesium glycinate or threonate are the most studied forms for sleep. Check what "four types" means before buying.
- Topical collagen does not penetrate the dermis. Oral or injected routes have more bioavailability data.
- Red light therapy at home varies significantly by device output. Consumer devices are often underpowered versus clinical studies.