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Originally posted by @drtodd_newyorkcityy on Instagram · 75s|Watch on Instagram
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Auto-generated transcript of @drtodd_newyorkcityy's video. Quoted here for educational fact-check commentary; original creator retains all rights to the video content.

  1. 0:00Tell me if you've ever heard this on social media.
  2. 0:02Don't get this treatment, it's gonna create scar tissue
  3. 0:05and you'll never be able to get a facelift.
  4. 0:08Skin tightening.
  5. 0:10You hear a lot of different things on social media,
  6. 0:12but what's really the truth?
  7. 0:14Sometimes you hear plastic surgeons
  8. 0:16saying never get any skin tightening treatment
  9. 0:18and close to close to scars.
  10. 0:20Or what's the difference between
  11. 0:21an aesthetic control procedure and scar tissue
  12. 0:25when we look at the collagen itself?
  13. 0:27Aesthetic treatment.
  14. 0:28Microneedling RF, microneedling lasers,
  15. 0:31biostimulus, create collagen typically of type one in three.
  16. 0:34It's precise, it's located and it occurs mildly
  17. 0:39over a long period of time.
  18. 0:41It's nice and gradual.
  19. 0:42Scar tissue typically from trauma, surgical or other causes
  20. 0:47that develop scar tissue.
  21. 0:48It occurs abruptly, it's uncontrolled, it's severely prolonged.
  22. 0:53It's a complex matrix that forms very acutely
  23. 0:56and uncontrollably.
  24. 0:58So there's a difference between a controlled response
  25. 1:00and an uncontrolled response that's defensive and healing
  26. 1:04and often over-producers resulting in scar tissue
  27. 1:09versus collagen stimulation from a medical aesthetic treatment.
  28. 1:13What do you think?

Dr Todd's collagen treatment claims need more nuance

Dr Todd Schlifstein

Instagram creator

337.1K viewsView on Instagram

Quick answer

RF microneedling, fractional lasers, and injectable biostimulants like poly-L-lactic acid (Sculptra) and calcium hydroxylapatite (Radiesse) work by inducing a controlled micro-injury that activates fibroblasts and stimulates organized type I and type III collagen synthesis over weeks to months. This process is biologically distinct from pathological scarring, which involves dysregulated TGF-beta1 signaling, prolonged myofibroblast persistence, and disorganized collagen deposition. However, the risk of abnormal collagen response is not zero, and is meaningfully elevated in patients with keloid history, active inflammatory skin conditions, or when treatments are performed aggressively or outside recommended parameters.

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This page currently connects to 5 source-backed evidence items through visible references or structured citation data.

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Dr Todd's collagen treatment claims need more nuance should be treated as a claim to verify, then compared with evidence, safety context, and a provider review path.

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What this exact clip is really saying

This FormBlends review is specific to "Dr Todd's collagen treatment claims need more nuance" from Dr Todd Schlifstein. We read the clip as a Peptide social video fact-checks claim about Peptide social video fact-checks, then separate the useful signal from what a short social video cannot prove. The page-specific claim focus is: RF microneedling, fractional lasers, and injectable biostimulants like poly-L-lactic acid (Sculptra) and calcium hydroxylapatite (Radiesse) work by inducing a controlled micro-injury that activates fibroblasts and stimulates organized type I and type III collagen synthesis over weeks to months.

The reason this review is not generic is the source wording and the canonical claim label "peptides does collagen stimulating treatments cause scar tissue what." In this clip, the useful excerpt is: "Tell me if you've ever heard this on social media." That wording changes the review because it points to Peptide social video fact-checks evidence, safety, and patient-fit context, not a one-size-fits-all protocol.

The source trail for this page is checked against The human peptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging (2015), Effects of glycyl-histidyl-lysine-Cu on wound healing (Search), and Copper peptide and skin remodeling literature (Search), plus the creator's own wording. Peptide social video fact-checks decisions still need an eligibility review, medication-interaction screen, access check, and quality-control review before anyone treats a social clip as medical advice.

Pathological scar tissue involves TGF-beta1-driven myofibroblast persistence and disorganized collagen, a distinct process from controlled aesthetic neocollagenesis (Gauglitz et al.
People who land here are usually comparing the Peptide social video fact-checks claim with collagen, collagentreatment, and collagenstimulation.
The strongest next step is to compare the claim with FormBlends' Peptide social video fact-checks guide, evidence notes, and provider review path before acting.

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Claim being checked

RF microneedling, fractional lasers, and injectable biostimulants like poly-L-lactic acid (Sculptra) and calcium hydroxylapatite (Radiesse) work by inducing a controlled micro-injury that activates fibroblasts and stimulates organized type I and type III collagen synthesis over weeks to months.

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Use the clip as a claim to verify, not a treatment plan

What it helps with

  • RF microneedling, fractional lasers, and injectable biostimulants like poly-L-lactic acid (Sculptra) and calcium hydroxylapatite (Radiesse) work by inducing a controlled micro-injury that activates fibroblasts and stimulates organized type I and type III collagen synthesis over weeks to months. This process is biologically distinct from pathological scarring, which involves dysregulated TGF-beta1 signaling, prolonged myofibroblast persistence, and disorganized collagen deposition. However, the risk of abnormal collagen response is not zero, and is meaningfully elevated in patients with keloid history, active inflammatory skin conditions, or when treatments are performed aggressively or outside recommended parameters.
  • Type I and type III collagen synthesis from RF microneedling and fractional lasers is supported by peer-reviewed evidence, including Gold et al. (2017, Journal of Drugs in Dermatology), but collagen organization matters as much as type.
  • Pathological scar tissue involves TGF-beta1-driven myofibroblast persistence and disorganized collagen, a distinct process from controlled aesthetic neocollagenesis (Gauglitz et al., 2011, Molecular Medicine).

What it may miss

  • It may not cover eligibility, contraindications, medication interactions, lab history, or dose escalation.
  • Compound access, legal status, and product quality still need a separate safety check.
  • Social video captions rarely show the full evidence base behind a claim.

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What You'll Learn

  • Type I and type III collagen synthesis from RF microneedling and fractional lasers is supported by peer-reviewed evidence, including Gold et al. (2017, Journal of Drugs in Dermatology), but collagen organization matters as much as type.
  • Pathological scar tissue involves TGF-beta1-driven myofibroblast persistence and disorganized collagen, a distinct process from controlled aesthetic neocollagenesis (Gauglitz et al., 2011, Molecular Medicine).
  • A 2022 JAMA Dermatology case series documented delayed subcutaneous fibrosis after aggressive HIFU treatments, meaning the 'controlled' label depends heavily on operator skill and device settings.
  • Patients with a personal or family history of keloids or hypertrophic scarring face a genuinely elevated risk of abnormal collagen response even from FDA-cleared aesthetic devices.
  • The question of whether repeated energy-based treatments complicate future surgical dissection is unresolved. Anecdotal reports exist on both sides and the data is insufficient to make a definitive claim in either direction.
  • Biostimulants like Sculptra (poly-L-lactic acid) and Radiesse (calcium hydroxylapatite) work through different mechanisms than energy-based devices but also carry a risk of nodule formation if injected incorrectly, which is a form of uncontrolled tissue response.
  • Anyone combining long-term non-surgical treatments with plans for future surgical procedures should consult a board-certified plastic surgeon before starting treatment series, not after completing them.

Our take · Written by FormBlends editorial team · Reviewed by FormBlends Medical Team · This is not a transcript. It is our independent review of the video above.

What did @drtodd_newyorkcityy actually say?

The creator's core argument is that aesthetic collagen-stimulating treatments, things like RF microneedling, lasers, and biostimulants like Sculptra and Radiesse, do not produce scar tissue. The reasoning: these treatments generate a "controlled response" that creates type I and type III collagen "gradually" and "precisely," while actual scar tissue forms "abruptly" and "uncontrollably" from trauma or surgery. The video is a direct rebuttal to social media warnings, often from plastic surgeons, that skin tightening treatments will leave patients unable to get a facelift later. It's a reasonable question to address. The framing is mostly fair, though it glosses over some real nuances that matter clinically.

Does the science back this up?

Largely, yes. The biological distinction the creator draws is real. Normal wound healing and controlled aesthetic injury follow overlapping but meaningfully different pathways. Aesthetic devices are designed to induce a calibrated micro-injury that triggers fibroblast activation and collagen synthesis without triggering the prolonged inflammatory cascade associated with hypertrophic scarring or keloids.

A 2017 review by Gold et al. in the Journal of Drugs in Dermatology confirmed that fractional laser and RF microneedling treatments produce organized neocollagenesis primarily involving type I and type III collagen, with resolution of the acute inflammatory phase within days, not weeks. Pathological scarring, by contrast, involves dysregulated TGF-beta signaling, prolonged myofibroblast activity, and disorganized collagen cross-linking (Gauglitz et al., 2011, Molecular Medicine). The creator's summary of this is simplified but directionally correct.

Where it gets more complicated: the "controlled" nature of these treatments is operator-dependent. Aggressive energy settings, overlapping passes, or treatment over active acne or compromised skin can absolutely trigger an uncontrolled response. The technology is controlled. The application is not always.

What did they get wrong (or right)?

Credit where it's due: the distinction between type I and type III collagen in the context of aesthetic treatments versus scar tissue is a real and often misunderstood point. Scar tissue is disproportionately type I collagen in a disorganized, parallel arrangement. Aesthetic treatments ideally increase both types in a more basket-weave pattern that mimics young skin (Aust et al., 2008, Aesthetic Surgery Journal).

What's missing or oversimplified:

  • The creator says aesthetic treatments create collagen "typically of type one in three" but doesn't mention that the ratio and organization matter enormously. More collagen is not automatically better collagen.
  • The blanket reassurance that these treatments won't interfere with future surgery is not fully supported. Some plastic surgeons have documented increased fibrosis in subcutaneous tissue planes after repeated energy-based treatments, which can complicate dissection. This isn't universal, but dismissing the concern entirely is too confident.
  • No mention of risk stratification. Patients with a history of keloids, hypertrophic scarring, or active autoimmune conditions are genuinely at higher risk of abnormal collagen responses even from "controlled" procedures.

What should you actually know?

The creator is right that "scar tissue" is not an inevitable outcome of collagen-stimulating aesthetic treatments when performed correctly on appropriate candidates. The biological pathways are different enough that the comparison is valid as a general principle.

But "controlled" is doing a lot of work in this explanation. A Ultherapy or RF microneedling treatment performed at the wrong depth, wrong energy, or on the wrong patient can produce subcutaneous fibrosis that looks nothing like the smooth remodeling shown in before-and-after photos. A 2022 case series in JAMA Dermatology documented delayed-onset nodule formation and subcutaneous fibrosis following aggressive HIFU treatments, which is a real-world reminder that operator skill and patient selection are not optional variables.

The surgical interference question is more nuanced than this video lets on. Some surgeons report no issues. Others have found that repeated energy-based treatments create adhesions in tissue planes used during facelifts. The honest answer is that the data is limited and largely anecdotal on both sides. Anyone considering a long-term combination of non-surgical treatments and potential future surgery should have that specific conversation with a board-certified plastic surgeon before starting a treatment series, not after.

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About the Creator

Dr Todd Schlifstein · Instagram creator

337.1K views on this video

Does collagen stimulating treatments cause scar tissue? What do you think ? We hear a lot about collegenan stimulating treatments whether it’s bio stimulants, energy based devices, lasers, regenerativ

Frequently asked questions

Quick answers based on this video and our medical team review.

What does the video say about type i?

Type I and type III collagen synthesis from RF microneedling and fractional lasers is supported by peer-reviewed evidence, including Gold et al. (2017, Journal of Drugs in Dermatology), but collagen organization matters as much as type.

What does the video say about pathological scar tissue involves tgf-beta1-driven myofibroblast persistence?

Pathological scar tissue involves TGF-beta1-driven myofibroblast persistence and disorganized collagen, a distinct process from controlled aesthetic neocollagenesis (Gauglitz et al., 2011, Molecular Medicine).

What does the video say about a 2022 jama dermatology case series documented delayed subcutaneous fibrosis?

A 2022 JAMA Dermatology case series documented delayed subcutaneous fibrosis after aggressive HIFU treatments, meaning the 'controlled' label depends heavily on operator skill and device settings.

What does the video say about patients with a personal?

Patients with a personal or family history of keloids or hypertrophic scarring face a genuinely elevated risk of abnormal collagen response even from FDA-cleared aesthetic devices.

What does the video say about the question of whether repeated energy-based treatments complicate future surgical?

The question of whether repeated energy-based treatments complicate future surgical dissection is unresolved. Anecdotal reports exist on both sides and the data is insufficient to make a definitive claim in either direction.

What does the video say about biostimulants like sculptra (poly-l-lactic acid)?

Biostimulants like Sculptra (poly-L-lactic acid) and Radiesse (calcium hydroxylapatite) work through different mechanisms than energy-based devices but also carry a risk of nodule formation if injected incorrectly, which is a form of uncontrolled tissue response.

Sources & references

Citations extracted from our medical team's review. Click any citation to search PubMed.

Educational use only. This fact-check is editorial content for general information. Nothing here is medical advice. Talk to a licensed provider about your specific situation before starting, stopping, or changing any supplement, peptide, or medication regimen.

Read More on This Topic

Our written guides go deeper with dosing details, comparison tables, and medical-team reviewed protocols.

Not medical advice. This video was made by Dr Todd Schlifstein, not by FormBlends. Our write-up above is an editorial review, not a medical recommendation. Talk to your doctor before making any decisions about medications or treatments.