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Originally posted by @onehottrail on Instagram · 83s|Watch on Instagram
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Auto-generated transcript of @onehottrail's video. Quoted here for educational fact-check commentary; original creator retains all rights to the video content.

  1. 0:00I'm mega dose seed oils to see if it would affect my testosterone levels.
  2. 0:03One of the biggest concerns with seed oils is the overconsumption of the polyunsaturated
  3. 0:07omega-6 fatty acid known as linoleic acid.
  4. 0:10As you can see from my levels, it is almost above the normal reference rate.
  5. 0:14I accomplished this through a dirty bulk where I went from approximately 165 to 190 pounds
  6. 0:19nearing obesity BMI, definitely pushing 20% body fat in my opinion.
  7. 0:24Fasting blood glucose remained the same while two of my liver function markers significantly
  8. 0:28increased.
  9. 0:29Khemoglobin A1C took a hit as it went from 4.9 to 5.1 and my insulin remained the same.
  10. 0:34Total cholesterol, triglycerides and LDL or my bad cholesterol all increased while HDL,
  11. 0:39my good cholesterol, pretty much remained the same.
  12. 0:42Estradyl increased from 35 to 41.
  13. 0:44Both can now trope in significantly increased especially my loonizing hormone which is responsible
  14. 0:48for stimulating the lading cells to produce testosterone.
  15. 0:51And lastly, SHBG decreased as well.
  16. 0:53This all led to my total testosterone decreasing to 937 and free to 19.41 nanograms per deciliter
  17. 0:59which is still amazing especially when you take into account that I was only working out
  18. 1:03on average 2 to 3 times per week.
  19. 1:05If I was working out more even consuming more omega-3 so that my omega-3-6 ratio improved,
  20. 1:10I likely would have seen even better results.
  21. 1:13The main point from this experiment is that chronic overconsumption of any foods can lead
  22. 1:16to negative outcomes but for the average healthy adult, the typical seed oil intake should not
  23. 1:20likely lead to any negative results.

Do seed oils actually lower testosterone? We checked

OneHot

Instagram creator

17.5K viewsView on Instagram

Quick answer

This creator's testosterone decline from an implied higher baseline to 937 ng/dL occurred alongside a 25-pound weight gain to approximately 20% body fat, rising estradiol, and worsening lipid markers, a hormonal pattern consistent with obesity-related hypogonadotropic changes rather than a specific dietary fatty acid effect. SHBG suppression with fat gain is well documented and would affect free testosterone independently of linoleic acid intake. A clinician evaluating these labs would focus on body composition, not seed oil consumption, as the primary modifiable variable.

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What this exact clip is really saying

This FormBlends review is specific to "Do seed oils actually lower testosterone? We checked" from OneHot. We read the clip as a TRT social video fact-checks claim about Testosterone, then separate the useful signal from what a short social video cannot prove. The page-specific claim focus is: This creator's testosterone decline from an implied higher baseline to 937 ng/dL occurred alongside a 25-pound weight gain to approximately 20% body fat, rising estradiol, and worsening lipid markers, a hormonal pattern consistent with obesity-related hypogonadotropic changes rather than a specific dietary fatty acid effect.

The reason this review is not generic is the source wording and the canonical claim label "trt do seed oils lower testosterone levels lastofthenattys." In this clip, the useful excerpt is: "I'm mega dose seed oils to see if it would affect my testosterone levels." That wording changes the review because it points to Testosterone evidence, safety, and patient-fit context, not a one-size-fits-all protocol.

The source trail for this page is checked against Cardiovascular Safety of Testosterone-Replacement Therapy (2023), Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline (2010), and Functional testosterone deficiency in aging men: Clinical impact, diagnostic pathways, and treatment strategies (2026), plus the creator's own wording. Testosterone decisions still need an eligibility review, medication-interaction screen, access check, and quality-control review before anyone treats a social clip as medical advice.

A 25-pound fat gain to approximately 20% body fat is independently sufficient to suppress testosterone and raise estradiol via aromatase activity, regardless of dietary fat source.
People who land here are usually comparing the Testosterone claim with lastofthenattys, testosterone, and testosteronebooster.
The strongest next step is to compare the claim with FormBlends' Testosterone guide, evidence notes, and provider review path before acting.

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This page is built to answer the specific claim behind the clip, then separate what is useful from what still needs clinical context. That makes the URL more than a repost: it gives Google, readers, and AI retrieval systems a concise verdict with source and safety boundaries.

Claim being checked

This creator's testosterone decline from an implied higher baseline to 937 ng/dL occurred alongside a 25-pound weight gain to approximately 20% body fat, rising estradiol, and worsening lipid markers, a hormonal pattern consistent with obesity-related hypogonadotropic changes rather than a specific dietary fatty acid effect.

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Testosterone evidence, safety, and patient-fit context

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What it helps with

  • This creator's testosterone decline from an implied higher baseline to 937 ng/dL occurred alongside a 25-pound weight gain to approximately 20% body fat, rising estradiol, and worsening lipid markers, a hormonal pattern consistent with obesity-related hypogonadotropic changes rather than a specific dietary fatty acid effect. SHBG suppression with fat gain is well documented and would affect free testosterone independently of linoleic acid intake. A clinician evaluating these labs would focus on body composition, not seed oil consumption, as the primary modifiable variable.
  • 937 ng/dL total testosterone is well within the normal adult male range of 300-1000 ng/dL, making this an ambiguous endpoint for demonstrating harm from seed oils.
  • A 25-pound fat gain to approximately 20% body fat is independently sufficient to suppress testosterone and raise estradiol via aromatase activity, regardless of dietary fat source.

What it may miss

  • It may not cover eligibility, contraindications, medication interactions, lab history, or dose escalation.
  • Compound access, legal status, and product quality still need a separate safety check.
  • Social video captions rarely show the full evidence base behind a claim.

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What You'll Learn

  • 937 ng/dL total testosterone is well within the normal adult male range of 300-1000 ng/dL, making this an ambiguous endpoint for demonstrating harm from seed oils.
  • A 25-pound fat gain to approximately 20% body fat is independently sufficient to suppress testosterone and raise estradiol via aromatase activity, regardless of dietary fat source.
  • Hu et al., 2021, Obesity Reviews, found that adiposity reliably increases aromatase-driven testosterone-to-estradiol conversion, the most plausible explanation for his hormonal changes here.
  • Linoleic acid in controlled human trials tends to lower LDL cholesterol, not raise it. His rising LDL is more consistent with caloric surplus and saturated fat intake during a dirty bulk than with omega-6 consumption specifically.
  • The omega-3 to omega-6 ratio concept has biological plausibility but limited controlled trial evidence in humans specifically for testosterone outcomes at typical dietary intakes.
  • Self-experiments with multiple simultaneous dietary and body composition changes cannot isolate individual variables. This video is an n-of-1 diary, not a seed oil intervention study.
  • Anyone experiencing symptoms of low testosterone, fatigue, reduced libido, or mood changes should get a proper hormonal panel interpreted by a clinician rather than drawing conclusions from social media self-experiments.

Our take · Written by FormBlends editorial team · Reviewed by FormBlends Medical Team · This is not a transcript. It is our independent review of the video above.

What did @onehottrail actually say?

The short version: he deliberately overconsumed seed oils during a dirty bulk, gained roughly 25 pounds, and watched his total testosterone drop from an unstated baseline to 937 ng/dL. His conclusion was measured: "chronic overconsumption of any foods can lead to negative outcomes" but typical seed oil intake probably won't hurt a healthy adult. That's a more responsible takeaway than most testosterone content on this platform delivers.

He tracked linoleic acid intake, liver enzymes, hemoglobin A1C, insulin, lipids, estradiol, LH, FSH, SHBG, and both total and free testosterone. That's a genuinely thorough panel. He also acknowledged confounders: reduced training frequency, significant fat gain, and a worsening omega-3 to omega-6 ratio. The self-awareness here is above average for Instagram health content, even if the experiment design has serious problems.

Does the science back this up?

Partially, but the causal arrow is almost certainly pointing at body fat, not seed oils specifically. The data on linoleic acid and testosterone in humans is weak and inconsistent. The data on obesity suppressing testosterone is robust.

A 2021 meta-analysis by Hu et al. in Obesity Reviews confirmed that increased adiposity reliably elevates aromatase activity, converting testosterone to estradiol, which suppresses LH via negative feedback. His estradiol rising from 35 to 41 pg/mL and total testosterone falling are textbook consequences of going from roughly 10-12% to 20% body fat, regardless of what cooking oil he used.

On linoleic acid specifically: a 2021 review by Hamley in Prostaglandins, Leukotrienes and Essential Fatty Acids found no consistent evidence that dietary omega-6 intake suppresses testosterone in humans at realistic intake levels. Rodent studies showing linoleic acid effects on Leydig cell function exist, but rodent lipid metabolism differs enough from human physiology that extrapolating directly is a stretch most endocrinologists won't make.

What did they get wrong (or right)?

Credit where it's due: his final conclusion is basically correct. The wrong part is the framing of the experiment itself, which implies seed oils were the active variable when body fat gain almost certainly did the heavy lifting.

Going from 165 to 190 pounds while "nearing obesity BMI" and pushing 20% body fat is not a controlled seed oil intervention. It's a weight gain study with seed oil consumption as one uncontrolled dietary component among many. Calories increased substantially, processed food intake likely increased, sleep quality may have changed with weight gain, and training dropped to 2-3 sessions per week. Any one of those variables could explain his testosterone drop independently.

His lipid panel changes, specifically rising LDL and triglycerides, are also more consistent with caloric surplus and saturated fat co-consumption during a dirty bulk than with linoleic acid specifically. Linoleic acid in controlled trials tends to lower LDL, not raise it, per Mozaffarian et al., 2010, PLOS Medicine.

The interpretation of his LH increasing as a positive sign also deserves scrutiny. Elevated LH alongside falling testosterone can indicate primary testicular insufficiency or, more likely here, a compensatory response to suppressed free testosterone. It is not necessarily reassuring.

What should you actually know?

Seed oils are not the testosterone villain that corners of the internet insist they are. The anti-seed oil narrative has outrun the evidence considerably. That doesn't mean unlimited processed food consumption is fine, but the specific mechanism, linoleic acid directly suppressing Leydig cell function at normal dietary intakes, has not been established in controlled human trials.

What does reliably suppress testosterone is excess body fat. If someone gains 25 pounds of fat while eating anything, seed oils, butter, olive oil, or lard, they should expect their testosterone to trend downward and their estradiol to trend upward. The endocrinology here is well established. Adipose tissue expresses aromatase. More fat means more conversion of androgens to estrogens.

If you're concerned about your testosterone levels, the most evidence-backed lifestyle interventions remain resistance training, adequate sleep, maintaining a healthy body weight, and limiting chronic alcohol use. A clinician, not a self-experiment with uncontrolled variables, is the appropriate starting point for evaluating hypogonadism symptoms.

Bottom line: is this video worth your time?

More so than most testosterone content in this category. The creator ran real labs, acknowledged confounders, and landed on a reasonable conclusion. But the experiment cannot tell us what he implies it might tell us, because body fat gain and seed oil overconsumption were completely entangled. Treat it as an entertaining n-of-1 diary with a sensible moral, not as evidence about seed oils and testosterone.

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About the Creator

OneHot · Instagram creator

17.5K views on this video

Do seed oils lower testosterone levels? — #lastofthenattys #testosterone #testosteronebooster #naturaltestosterone #testosteronelevels #testosteroneboost #lowtestosterone #testosteroneoptimization #

Frequently asked questions

Quick answers based on this video and our medical team review.

What does the video say about 937 ng/dl total testosterone?

937 ng/dL total testosterone is well within the normal adult male range of 300-1000 ng/dL, making this an ambiguous endpoint for demonstrating harm from seed oils.

What does the video say about a 25-pound fat gain to approximately 20% body fat?

A 25-pound fat gain to approximately 20% body fat is independently sufficient to suppress testosterone and raise estradiol via aromatase activity, regardless of dietary fat source.

What does the video say about hu et al., 2021, obesity reviews, found?

Hu et al., 2021, Obesity Reviews, found that adiposity reliably increases aromatase-driven testosterone-to-estradiol conversion, the most plausible explanation for his hormonal changes here.

What does the video say about linoleic acid in controlled human trials tends to lower ldl?

Linoleic acid in controlled human trials tends to lower LDL cholesterol, not raise it. His rising LDL is more consistent with caloric surplus and saturated fat intake during a dirty bulk than with omega-6 consumption specifically.

What does the video say about the omega-3 to omega-6 ratio concept has biological plausibility?

The omega-3 to omega-6 ratio concept has biological plausibility but limited controlled trial evidence in humans specifically for testosterone outcomes at typical dietary intakes.

What does the video say about self-experiments with multiple simultaneous dietary?

Self-experiments with multiple simultaneous dietary and body composition changes cannot isolate individual variables. This video is an n-of-1 diary, not a seed oil intervention study.

Sources & references

Citations extracted from our medical team's review. Click any citation to search PubMed.

Educational use only. This fact-check is editorial content for general information. Nothing here is medical advice. Talk to a licensed provider about your specific situation before starting, stopping, or changing any supplement, peptide, or medication regimen.

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Not medical advice. This video was made by OneHot, not by FormBlends. Our write-up above is an editorial review, not a medical recommendation. Talk to your doctor before making any decisions about medications or treatments.