What did @tikdoctony actually say?
The creator claims a hubless "no-waste syringe" costing 21 cents eliminates what they call "10 units of testosterone" trapped in a standard syringe hub after every injection. They demo this with a green-dyed solution, show residual fluid in a conventional hub, and argue the savings extend to Botox, where they put the dollar figure at roughly $35 per wasted hub. They also say they use these syringes in their own med spa.
The visual demo is real and the underlying physics are sound: dead-space volume in syringe hubs is a documented phenomenon. The argument that hubless or low dead-space syringes reduce medication waste is not new or fringe. Where this video runs into trouble is the specific numbers, and how loosely the creator moves between "units" and volume without defining either clearly for the audience.
Does the science back this up?
Mostly, yes, but the magnitude of waste depends heavily on syringe type, and 10 units is a plausible but not universal figure. The dead-space problem is well-established in injection drug use harm-reduction research. A 2012 study by Zule et al. in the journal Drug and Alcohol Dependence measured hub dead-space volumes across syringe types and found conventional hub syringes retained between 0.03 and 0.13 mL of fluid, depending on design. Low dead-space syringes reduced that to near zero.
For insulin syringes, which are what most testosterone self-injectors use for subcutaneous dosing, a standard 0.5 mL insulin syringe hub holds roughly 0.03 to 0.05 mL. In insulin dosing, 0.05 mL equals 5 units on a U-100 scale. For testosterone dosed in milligrams rather than insulin units, the math shifts. At a typical concentration of 200 mg/mL testosterone cypionate, 0.05 mL equals 10 mg, not 10 units in the insulin sense. The creator conflates these two measurement systems throughout, which creates real confusion for patients managing their own injections.
What did they get wrong (or right)?
The creator gets the core concept right. Hub dead-space is real, low dead-space syringes exist, and wasted medication is a legitimate clinical and economic concern. Credit where it is due: the visual demo is honest and illustrates the concept clearly.
What they got wrong is the unit language. Saying "10 units" without specifying units of what is sloppy for a medical professional posting to a health audience. On a U-100 insulin syringe, 10 units equals 0.1 mL, which is on the high end of published dead-space measurements and overstates typical hub loss for most insulin syringes. If they mean 10 mg of testosterone at 200 mg/mL concentration, that is closer to accurate for some conventional syringes, but they never say that.
The Botox math is also shaky. They claim 5 units of Botox waste at $7 per unit equals $35 saved per syringe. Botox is typically drawn into a 1 mL syringe and diluted, so hub dead-space represents a much smaller fraction of the total reconstituted volume. Whether 5 Botox units actually sit in a hub depends entirely on dilution protocol. A 2019 review by Carruthers et al. in Dermatologic Surgery notes that reconstitution volume variability is a significant source of dosing inconsistency, but does not attribute it primarily to hub dead-space.
What should you actually know?
If you are self-injecting testosterone cypionate or enanthate as part of a supervised TRT protocol, the type of syringe you use does affect how much medication you actually receive. Low dead-space or hubless syringes are a real product category, and switching to them can improve dose consistency. This matters more at lower dose volumes, where hub waste is a larger percentage of the total draw.
That said, small dose variations from hub dead-space are unlikely to produce clinically meaningful hormone level swings in most patients on stable protocols. Your prescribing provider should be adjusting your dose based on lab values, not syringe geometry. If you are noticing unexplained variation in how you feel between injections, syringe type is worth discussing with your provider, but it sits well below factors like injection site, injection frequency, and baseline physiology in terms of clinical impact.
The 21-cent price point for a hubless syringe is plausible given bulk supply costs, though prices vary by vendor. Never purchase syringes from unverified sources, and do not change your injection technique, dose, or frequency without consulting the provider who manages your protocol.