TRT for penis size: what the science actually shows
Quick answer
Exogenous testosterone administration reliably suppresses gonadotropin signaling, leading to testicular volume reduction in most men on TRT protocols. This is a predictable physiological outcome, not an anomaly. Adult penile tissue does not respond to testosterone supplementation with growth, as the androgen-sensitive developmental window closes after puberty. Men considering TRT should discuss testicular atrophy, fertility implications, and hCG co-administration options with a qualified provider before starting therapy.
Our take · Written by FormBlends editorial team · Reviewed by FormBlends Medical Team· This is not a transcript. It is our independent review of the video above.
What did @jeremygoodmanmd actually say?
The claim here is actually two-part. First, TRT will not increase penile size. Second, testicular atrophy from TRT can create an optical illusion where the penis appears relatively larger because the testicles shrink. He also teases a separate procedure he calls "BPG" or "bigger pickle girth" as a penile filler option for men who actually want size gains.
To his credit, the core anatomical framing is correct. TRT does not grow penile tissue in adult men. And testicular atrophy is a well-documented, common side effect of exogenous testosterone. So the proportional visual change he describes is physiologically grounded, even if the delivery is pure TikTok bro-medicine.
The pivot to advertising penile filler at the end deserves its own scrutiny, which we'll get to.
Does the science back this up?
Yes, mostly. Exogenous testosterone suppresses the hypothalamic-pituitary-gonadal axis. When the brain stops signaling the testes to produce testosterone, the testes lose their primary functional stimulus and atrophy. This is not rare or theoretical. It is the expected physiological outcome.
Coviello et al. (2004, Journal of Clinical Endocrinology and Metabolism) demonstrated that exogenous testosterone administration significantly suppresses luteinizing hormone and follicle-stimulating hormone, directly causing testicular volume reduction. Studies on men undergoing androgen-based male contraception protocols have shown testicular volume decreases of 20-25% over several months of use.
On penile size: adult penile length is not meaningfully altered by testosterone in men with normal baseline androgen receptor function. Testosterone drives penile growth during puberty via androgen receptor stimulation, but once that developmental window closes, supplemental testosterone does not replicate that growth in adult tissue. A 2020 review in Sexual Medicine Reviews confirmed no evidence supports penile elongation from TRT in adult hypogonadal men.
What did they get wrong (or right)?
He got the testicular atrophy claim right. He got the "TRT won't grow your penis" claim right. Those are both accurate statements that many TRT enthusiasts either misunderstand or actively misrepresent online, so giving credit where it is due matters here.
What deserves scrutiny is the breezy segue into advertising "pickle filler," which appears to reference penile filler injections, a real but poorly regulated aesthetic procedure. Penile filler (typically hyaluronic acid-based) is not FDA-approved for this indication. Complications including lumping, asymmetry, vascular injury, and infection are well-documented in the literature. Egydio and Kuehhas (2018, International Journal of Impotence Research) reviewed outcomes and noted that complication rates vary widely depending on injector experience and product used.
Casually marketing this procedure under a cutesy acronym like "BPG" in a viral TikTok without disclosing those risks is a legitimate concern. The anatomy joke does not excuse the advertisement.
What should you actually know?
If you are on TRT or considering it, testicular atrophy is real and predictable. The degree varies by dose, frequency, and individual response. Human chorionic gonadotropin (hCG), when used alongside TRT, can preserve testicular volume by mimicking LH stimulation. Liu et al. (2002, Journal of Clinical Endocrinology and Metabolism) found that hCG co-administration maintained intratesticular testosterone and testicular size in men on exogenous testosterone protocols.
Fertility is a separate but related concern. Exogenous testosterone suppresses sperm production. Men who want to preserve fertility should have a frank conversation with a urologist or reproductive endocrinologist before starting TRT, not just a TikTok doctor.
On penile filler: if you are considering it, do not let a viral video be your informed consent. This is an off-label procedure with real complication potential. Research the provider's credentials, the specific product being used, and ask for their documented complication rate. This is not a spa service.
The bottom line
The core anatomy in this video is accurate. TRT does not enlarge the penis in adults, and testicular atrophy is a legitimate and common side effect that affects the visual proportion he describes. The science supports those points. What it does not support is treating penile filler as a casual upsell in a 30-second TikTok without any risk disclosure. The medical facts are fine. The marketing framing is not.
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This page currently connects to 9 source-backed evidence items through visible references or structured citation data.
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Cardiovascular Safety of Testosterone-Replacement Therapy
TRAVERSE trial anchor for cardiovascular-safety discussions in appropriately diagnosed men.
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Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline
Guideline anchor for diagnosis, monitoring, contraindications, and appropriate TRT framing.
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NAD+ metabolism and its roles in cellular processes during ageing
Core review for NAD+ decline, mitochondrial function, DNA repair, and aging biology.
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Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women
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TRT for penis size: what the science actually shows should be treated as a claim to verify, then compared with evidence, safety context, and a provider review path.
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Exogenous testosterone administration reliably suppresses gonadotropin signaling, leading to testicular volume reduction in most men on TRT protocols.
FormBlends verdict
Exogenous testosterone administration reliably suppresses gonadotropin signaling, leading to testicular volume reduction in most men on TRT protocols. This is a predictable physiological outcome, not an anomaly. Adult penile tissue does not respond to testosterone supplementation with growth, as the androgen-sensitive developmental window closes after puberty. Men considering TRT should discuss testicular atrophy, fertility implications, and hCG co-administration options with a qualified provider before starting therapy.
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What it helps with
- Exogenous testosterone administration reliably suppresses gonadotropin signaling, leading to testicular volume reduction in most men on TRT protocols. This is a predictable physiological outcome, not an anomaly. Adult penile tissue does not respond to testosterone supplementation with growth, as the androgen-sensitive developmental window closes after puberty. Men considering TRT should discuss testicular atrophy, fertility implications, and hCG co-administration options with a qualified provider before starting therapy.
- Testicular atrophy occurs in the majority of men on exogenous testosterone due to suppression of LH and FSH signaling through the HPG axis.
- Studies on testosterone-based male contraception protocols report testicular volume reductions of approximately 20-25% over months of use.
What it may miss
- It may not cover eligibility, contraindications, medication interactions, lab history, or dose escalation.
- Compound access, legal status, and product quality still need a separate safety check.
- Social video captions rarely show the full evidence base behind a claim.
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Compare the claim against a FormBlends guide, safety page, and licensed-provider review before acting.
Start provider reviewWhat You'll Learn
- Testicular atrophy occurs in the majority of men on exogenous testosterone due to suppression of LH and FSH signaling through the HPG axis.
- Studies on testosterone-based male contraception protocols report testicular volume reductions of approximately 20-25% over months of use.
- Adult penile tissue does not grow in response to TRT. The developmental androgen sensitivity window closes after puberty.
- hCG co-administration can partially preserve testicular volume and intratesticular testosterone, per Liu et al. (2002, JCEM).
- Exogenous testosterone suppresses sperm production. Men who want to maintain fertility should consult a urologist before starting TRT.
- Penile filler injections are off-label, not FDA-approved for this use, and carry documented complication risks including infection, asymmetry, and vascular injury.
- A viral TikTok video is not a substitute for individualized clinical evaluation before starting TRT or any aesthetic procedure.
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About the Creator
Jeremy Goodman MD · TikTok creator
252.8K views on this video
TRT = Bigger gains… down there too? 🥒 #T#TRTM#MensHealthT#TestosteroneH#HormoneHealthM#MensWellnessT#TRTJourneyT#TRTResultsH#HealthTipsT#TRTCommunityM#MensPerformanceT#TRTSupportB#BoostTestosteroneM#
Sources & references
Citations extracted from our medical team's review. Click any citation to search PubMed.
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Our written guides go deeper with dosing details, comparison tables, and medical-team reviewed protocols.
Not medical advice. This video was made by Jeremy Goodman MD, not by FormBlends. Our write-up above is an editorial review, not a medical recommendation. Talk to your doctor before making any decisions about medications or treatments.