What does the video say about proper injection technique matters more than the specific muscle group?

Proper injection technique matters more than the specific muscle group chosen

Originally posted by @highwestmedical on TikTok · 62s|Watch on TikTok

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Auto-generated transcript of @highwestmedical's video. Quoted here for educational fact-check commentary; original creator retains all rights to the video content.

0:00Okay, so we put on a 25 gauge needle for the injection, and so we're going to show you
0:06how you find the muscle when you want to inject your testosterone into the glue.
0:09So you're looking for the upper kind of one-fourth of the glue muscle, and what you can do is
0:17you or the patient can put their hand right here, try to kick your leg back, perfect,
0:23and when they kick back, that muscle flexes, and that's right where you want to do that
0:27injection. You're going to feel that big glue muscle.
0:29Okay, so once you find that muscle, you're going to just pick a spot right there, and
0:34you're going to pinch nice and hard. The harder you pinch, the easier the injection actually
0:38feels, and you're just going to go straight in at a 90 degree angle. On the injection,
0:44you're going to push the needle all the way in until you hit the end of the needle, and
0:49then you're going to push the syringe and push the fluid all the way in, and it's very
0:54thick fluid so it can take a minute for it to push all the way in. And then when you're
0:58done, you're just going to hold on and pull that needle all the way out.

@highwestmedical's upper glute injection claims fact-checked

Name: @highwestmedical's upper glute injection claims fact-checked
Uploaded: 2025-10-13T15:58:18.000Z
Duration: 62 s
Description: Testosterone replacement therapy typically uses intramuscular injections of testosterone cypionate or enanthate every 7-14 days. Multiple injection sites are anatomically safe and provide equivalent pharmacokinetics, with site rotation recommended to prevent tissue damage.

Kirsten Nelson

TikTok creator

22.4K viewsWatch on TikTok →

Quick answer

Testosterone replacement therapy typically uses intramuscular injections of testosterone cypionate or enanthate every 7-14 days. Multiple injection sites are anatomically safe and provide equivalent pharmacokinetics, with site rotation recommended to prevent tissue damage.

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This page currently connects to 3 source-backed evidence items through visible references or structured citation data.

PubMed evidence trail

Research sources used to frame this page

For @highwestmedical's upper glute injection claims fact-checked, FormBlends checks the page topic against primary trials, systematic reviews, guidelines, and current PubMed-indexed literature where available. These citations are context, not medical advice, proof of eligibility, or a claim that every study applies to every patient.

Randomized trialTestosterone and TRT evidence2023

Cardiovascular Safety of Testosterone-Replacement Therapy

TRAVERSE trial anchor for cardiovascular-safety discussions in appropriately diagnosed men.

PubMed

GuidelineTestosterone and TRT evidence2010

Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline

Guideline anchor for diagnosis, monitoring, contraindications, and appropriate TRT framing.

PubMed

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@highwestmedical's upper glute injection claims fact-checked should be treated as a claim to verify, then compared with evidence, safety context, and a provider review path.

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Page-specific review note

What this exact clip is really saying

This FormBlends review is specific to "@highwestmedical's upper glute injection claims fact-checked" from Kirsten Nelson. We read the clip as a TRT social video fact-checks claim about Testosterone, then separate the useful signal from what a short social video cannot prove. The page-specific claim focus is: Testosterone replacement therapy typically uses intramuscular injections of testosterone cypionate or enanthate every 7-14 days.

The reason this review is not generic is the source wording and the canonical claim label "trt why the upper glute using the upper glute muscle is benefi." In this clip, the useful excerpt is: "Okay, so we put on a 25 gauge needle for the injection, and so we're going to show you how you find the muscle when you want to inject your testosterone into the glue." That wording changes the review because it points to Testosterone evidence, safety, and patient-fit context, not a one-size-fits-all protocol.

The source trail for this page is checked against Cardiovascular Safety of Testosterone-Replacement Therapy (2023), Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline (2010), and Functional testosterone deficiency in aging men: Clinical impact, diagnostic pathways, and treatment strategies (2026), plus the creator's own wording. Testosterone decisions still need an eligibility review, medication-interaction screen, access check, and quality-control review before anyone treats a social clip as medical advice.

Testosterone absorption rates are equivalent between properly administered intramuscular injection sites

People who land here are usually comparing the Testosterone claim with [object Object].

The strongest next step is to compare the claim with FormBlends' Testosterone guide, evidence notes, and provider review path before acting.

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Claim being checked

Testosterone replacement therapy typically uses intramuscular injections of testosterone cypionate or enanthate every 7-14 days.

FormBlends verdict

Testosterone evidence, safety, and patient-fit context

Evidence strength

Source-backed review with clinical or regulatory citations.

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Compare the claim with FormBlends safety guidance and a licensed-provider review before acting.

What to do with this video

Use the clip as a claim to verify, not a treatment plan

What it helps with

Testosterone replacement therapy typically uses intramuscular injections of testosterone cypionate or enanthate every 7-14 days. Multiple injection sites are anatomically safe and provide equivalent pharmacokinetics, with site rotation recommended to prevent tissue damage.
The upper glute (ventrogluteal site) is anatomically safer than the lower glute for injections
Testosterone absorption rates are equivalent between properly administered intramuscular injection sites

What it may miss

It may not cover eligibility, contraindications, medication interactions, lab history, or dose escalation.
Compound access, legal status, and product quality still need a separate safety check.
Social video captions rarely show the full evidence base behind a claim.

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What You'll Learn

The upper glute (ventrogluteal site) is anatomically safer than the lower glute for injections
Testosterone absorption rates are equivalent between properly administered intramuscular injection sites
Site rotation between different muscles prevents scar tissue buildup and absorption problems
The ventrogluteal site avoids the sciatic nerve, which runs through the lower buttock area
Comfort levels are generally better with upper glute compared to lower glute injections
Outer thigh injections may be more practical for self-administration than upper glute
Proper injection technique matters more than the specific muscle group chosen

Our take · Written by FormBlends editorial team · Reviewed by FormBlends Medical Team · This is not a transcript. It is our independent review of the video above.

What does this video actually claim?

Kirsten Nelson from @highwestmedical says the upper glute is the best injection site for testosterone because it's large, well-vascularized, allows better absorption, and reduces the risk of hitting nerves or blood vessels.

She's promoting this as safer and more comfortable than other injection sites. The video has 22.4K views and is clearly marketing High West Medical's testosterone therapy services. Let's see if the anatomy claims hold up.

Does the science back this up?

The upper glute (ventrogluteal site) is actually well-supported in medical literature, but not always for the reasons Nelson gives. A 2019 systematic review by Taddio et al. in Clinical Therapeutics found the ventrogluteal site had lower pain scores compared to dorsogluteal injections.

The anatomy is solid too. The ventrogluteal site avoids the sciatic nerve and superior gluteal artery, which are genuine risks with poorly placed dorsogluteal injections. A 2016 study in the International Journal of Nursing Studies (Cocoman & Murray) confirmed this site has fewer major blood vessels and nerves.

However, testosterone absorption rates don't vary significantly between properly administered intramuscular injection sites. The pharmacokinetics are nearly identical whether you inject in the glute, thigh, or deltoid.

What did they get wrong about absorption?

Nelson's claim about "better absorption" in the upper glute isn't backed by evidence. Testosterone cypionate and enanthate are oil-based preparations that absorb at similar rates regardless of the muscle group used.

A 2017 pharmacokinetic study (Dobs et al., Journal of Clinical Endocrinology & Metabolism) compared testosterone injection sites and found no clinically significant differences in peak levels or area under the curve. The absorption rate depends on the ester (cypionate vs. enanthate), not the muscle.

The "well-vascularized" argument also doesn't hold water for intramuscular testosterone. These are depot injections designed to release slowly over 7-10 days. More blood flow would actually speed up absorption, potentially shortening the duration between needed injections.

What did they get right about safety?

Nelson is absolutely correct about nerve and blood vessel safety. The ventrogluteal site is the gold standard for intramuscular injections precisely because it avoids major anatomical structures.

The sciatic nerve runs through the dorsogluteal area (what most people think of as the "butt cheek"), making ventrogluteal placement much safer. Multiple nursing textbooks and the World Health Organization recommend this site for exactly the reasons Nelson mentions.

The comfort factor is real too. Patients report less post-injection pain with ventrogluteal compared to dorsogluteal placement, according to multiple comparative studies in nursing journals.

What should you actually know?

The upper glute is a good injection site, but it's not magic. Any properly administered intramuscular injection will deliver testosterone effectively. The deltoid and vastus lateralis (outer thigh) work just as well for absorption.

Site rotation is actually more important than picking the "perfect" spot. Using the same location repeatedly can cause scar tissue buildup and actual absorption problems. Most protocols recommend rotating between 2-3 different sites.

If you're doing self-injections, the outer thigh might be more practical than trying to reach your upper glute. The key is proper technique, not the specific muscle group.

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About the Creator

Kirsten Nelson · TikTok creator

22.4K views on this video

Why the Upper Glute? Using the upper glute muscle is beneficial because it is large and well-vascularized, allowing for better absorption of testosterone. It also minimizes the risk of hitting nerves

Frequently asked questions

Quick answers based on this video and our medical team review.

What does the video say about the upper glute (ventrogluteal site)?

The upper glute (ventrogluteal site) is anatomically safer than the lower glute for injections

What does the video say about testosterone absorption rates?

Testosterone absorption rates are equivalent between properly administered intramuscular injection sites

What does the video say about site rotation between different muscles prevents scar tissue buildup?

Site rotation between different muscles prevents scar tissue buildup and absorption problems

What does the video say about the ventrogluteal site avoids the sciatic nerve,?

The ventrogluteal site avoids the sciatic nerve, which runs through the lower buttock area

What does the video say about comfort levels?

Comfort levels are generally better with upper glute compared to lower glute injections

What does the video say about outer thigh injections may be more practical for self-administration than?

Outer thigh injections may be more practical for self-administration than upper glute

Educational use only. This fact-check is editorial content for general information. Nothing here is medical advice. Talk to a licensed provider about your specific situation before starting, stopping, or changing any supplement, peptide, or medication regimen.