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Auto-generated transcript of @3hotflushes's video. Quoted here for educational fact-check commentary; original creator retains all rights to the video content.
- 0:00All men listening will be glad to know that there is such a thing as the male men of course,
- 0:04and it's called the Andra Pause. As we age, our hormones fall and fluctuate and men
- 0:10also have hormones that fall and fluctuate, namely testosterone. So the kind of concept of a grumpy
- 0:17old man, for those who are old enough, Victor Meldrew is not a figment of complete imagination,
- 0:23that there is such a thing. And unfortunately, it's even less research than men of course,
- 0:27we moan about there not being enough research, they're not being enough awareness, they're not
- 0:30enough education around our menopause. And Andra Pause has even less. But yes, if we talk about
- 0:36men and menopause, we do have to at my amterapause and give them some brownie points for it. We're
- 0:41going through something as well.
Andropause vs menopause: what the testosterone research actually shows
Quick answer
The creator describes age-related testosterone decline in men as "andropause," a lay term not used in clinical guidelines, where late-onset hypogonadism (LOH) is the preferred diagnosis requiring confirmed low testosterone plus specific symptoms. Unlike menopause, which is a universal physiological event, LOH affects an estimated 2% of middle-aged men by clinical criteria (Wu et al., 2010, NEJM). The claim that andropause is under-researched relative to menopause is broadly accurate, though the definitional inconsistency in the literature itself partly explains the research gap.
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This page currently connects to 9 source-backed evidence items through visible references or structured citation data.
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Cardiovascular Safety of Testosterone-Replacement Therapy
TRAVERSE trial anchor for cardiovascular-safety discussions in appropriately diagnosed men.
PubMed
Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline
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NAD+ metabolism and its roles in cellular processes during ageing
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Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women
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Andropause vs menopause: what the testosterone research actually shows should help you decide which option deserves a clinical review, not force a one-size answer.
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What this exact clip is really saying
This FormBlends review is specific to "Andropause vs menopause: what the testosterone research actually shows" from 3 Hot Flushes. We read the clip as a TRT social video fact-checks claim about Testosterone, then separate the useful signal from what a short social video cannot prove. The page-specific claim focus is: The creator describes age-related testosterone decline in men as "andropause," a lay term not used in clinical guidelines, where late-onset hypogonadism (LOH) is the preferred diagnosis requiring confirmed low testosterone plus specific symptoms.
The reason this review is not generic is the source wording and the canonical claim label "trt yes men have hormonal changes too it s called andropause as." In this clip, the useful excerpt is: "All men listening will be glad to know that there is such a thing as the male men of course, and it's called the Andra Pause." That wording changes the review because it points to Testosterone evidence, safety, and patient-fit context, not a one-size-fits-all protocol.
The source trail for this page is checked against Cardiovascular Safety of Testosterone-Replacement Therapy (2023), Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline (2010), and Functional testosterone deficiency in aging men: Clinical impact, diagnostic pathways, and treatment strategies (2026), plus the creator's own wording. Testosterone decisions still need an eligibility review, medication-interaction screen, access check, and quality-control review before anyone treats a social clip as medical advice.
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Claim being checked
The creator describes age-related testosterone decline in men as "andropause," a lay term not used in clinical guidelines, where late-onset hypogonadism (LOH) is the preferred diagnosis requiring confirmed low testosterone plus specific symptoms.
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Testosterone evidence, safety, and patient-fit context
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What it helps with
- The creator describes age-related testosterone decline in men as "andropause," a lay term not used in clinical guidelines, where late-onset hypogonadism (LOH) is the preferred diagnosis requiring confirmed low testosterone plus specific symptoms. Unlike menopause, which is a universal physiological event, LOH affects an estimated 2% of middle-aged men by clinical criteria (Wu et al., 2010, NEJM). The claim that andropause is under-researched relative to menopause is broadly accurate, though the definitional inconsistency in the literature itself partly explains the research gap.
- Testosterone declines approximately 1-2% per year after age 30, per the Massachusetts Male Aging Study (Feldman et al., 2002), but most men never reach a clinically symptomatic threshold.
- Only about 2% of men aged 40-79 meet clinical criteria for late-onset hypogonadism with confirmed symptoms, far lower than the near-universal experience of menopause (Wu et al., 2010, NEJM).
What it may miss
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Start provider reviewWhat You'll Learn
- Testosterone declines approximately 1-2% per year after age 30, per the Massachusetts Male Aging Study (Feldman et al., 2002), but most men never reach a clinically symptomatic threshold.
- Only about 2% of men aged 40-79 meet clinical criteria for late-onset hypogonadism with confirmed symptoms, far lower than the near-universal experience of menopause (Wu et al., 2010, NEJM).
- Clinicians use 'late-onset hypogonadism,' not 'andropause.' Walking into a GP appointment using the wrong term can create unnecessary friction.
- Diagnosis requires two separate morning blood draws confirming low testosterone, plus documented symptoms. A single low reading is insufficient (Bhasin et al., 2018, Endocrine Society guidelines).
- Symptoms of low testosterone overlap heavily with depression, sleep apnea, obesity, and thyroid dysfunction. These must be excluded before attributing symptoms to hormonal decline.
- TRT is a regulated medical treatment with documented risks including polycythemia, infertility, and potential cardiovascular effects. It requires clinical supervision, not self-diagnosis.
- Research on male hormonal aging is genuinely underfunded relative to menopause, but the inconsistent definition of the syndrome itself is part of why the evidence base remains weak.
Our take · Written by FormBlends editorial team · Reviewed by FormBlends Medical Team · This is not a transcript. It is our independent review of the video above.
What did @3hotflushes actually say?
The creator claims that men experience a hormonal transition called "andropause," driven by falling and fluctuating testosterone, and that this condition is even less researched than menopause. She uses the cultural shorthand of the "grumpy old man" to suggest real biological underpinning, and frames andropause as deserving more recognition alongside menopause.
This is a broadly reasonable position, though it carries some imprecision worth unpacking. The word "andropause" is contested in clinical medicine, and the creator's framing that testosterone "falls and fluctuates" the same way estrogen does in menopause is only partially accurate. The physiology is genuinely different, and collapsing the two can mislead listeners about what they should expect or seek treatment for.
Does the science back this up?
Partially, yes. Testosterone does decline with age in men, roughly 1-2% per year after age 30, according to data from the Massachusetts Male Aging Study (Feldman et al., 2002, Journal of Clinical Endocrinology and Metabolism). But this is a gradual slope, not a cliff. Unlike menopause, there is no universal hormonal event. Most men never drop into a clinically symptomatic range.
The preferred clinical term is "late-onset hypogonadism" (LOH), not andropause. The European Association of Urology and the American Urological Association both use LOH because "andropause" implies a defined biological transition that simply does not exist for most men. A large review by Wu et al. (2010, New England Journal of Medicine) found that only about 2% of men aged 40-79 met the criteria for LOH with symptoms. That is a far cry from the near-universal experience of menopause. The creator is right that research is thin, but the research gap is partly because the syndrome itself is inconsistently defined.
What did they get wrong (or right)?
Credit where it is due: the creator is right that male hormonal aging is real, under-discussed, and affects mood and energy. The Victor Meldrew reference is a decent pop-culture shortcut for explaining behavioral correlates of low testosterone. She is also right that acknowledging male hormonal changes does not diminish menopause advocacy.
Where she oversimplifies: testosterone does not "fluctuate" the way estrogen and progesterone do in perimenopause. Testosterone varies within a single day, peaking in the morning and dropping by afternoon, which is a normal diurnal rhythm, not a pathological fluctuation. Conflating daily variation with age-related decline could push men toward unnecessary testing or treatment. Also, calling it "andropause" without flagging that clinicians don't actually use that term is a small but meaningful omission. Patients who walk into a GP's office asking about their "andropause" may be met with confusion or dismissal, not because the concern is invalid, but because the terminology does not match the clinical framework.
What should you actually know?
If you are a man experiencing fatigue, low mood, reduced libido, or changes in body composition after 40, it is worth getting total and free testosterone measured, ideally on two separate mornings before 10am, since levels are highest then. A single low reading is not diagnostic. The Endocrine Society guidelines (Bhasin et al., 2018, Journal of Clinical Endocrinology and Metabolism) recommend confirming low testosterone with a second test and assessing for symptoms before considering any treatment.
Testosterone replacement therapy (TRT) is a regulated medical treatment with real risks, including effects on fertility, red blood cell count, and cardiovascular health. It is not a wellness supplement. Anyone considering it should be working with a clinician who does proper baseline bloodwork, not self-diagnosing off a TikTok video, however well-intentioned. The creator does not recommend TRT here, which is appropriate given the platform.
- Symptoms overlap with depression, sleep apnea, and thyroid disorders, all of which should be ruled out first.
- "Andropause" is not a recognized clinical diagnosis in the way menopause is.
- Research on late-onset hypogonadism is improving, but treatment thresholds remain debated.
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About the Creator
3 Hot Flushes · TikTok creator
147.1K views on this video
“Yes... Men have hormonal changes, too.” It’s called andropause. As men age, testosterone can fall and fluctuate, affecting mood, energy and well-being. It’s real, it’s under-researched, and it deserves understanding too. Acknowledging andropause doesn’t take away from menopause; it helps everyone understand each other better. 🎧 Full episode on Spotify. 🎥 Watch on YouTube. #andropause #menopauseeducation #podcast #health
Frequently asked questions
Quick answers based on this video and our medical team review.
What does the video say about testosterone declines approximately 1-2% per year after age 30, per?
Testosterone declines approximately 1-2% per year after age 30, per the Massachusetts Male Aging Study (Feldman et al., 2002), but most men never reach a clinically symptomatic threshold.
What does the video say about only about 2% of men aged 40-79 meet clinical criteria?
Only about 2% of men aged 40-79 meet clinical criteria for late-onset hypogonadism with confirmed symptoms, far lower than the near-universal experience of menopause (Wu et al., 2010, NEJM).
What does the video say about clinicians use 'late-onset hypogonadism,' not 'andropause.' walking into a gp?
Clinicians use 'late-onset hypogonadism,' not 'andropause.' Walking into a GP appointment using the wrong term can create unnecessary friction.
What does the video say about diagnosis requires two separate morning blood draws confirming low testosterone,?
Diagnosis requires two separate morning blood draws confirming low testosterone, plus documented symptoms. A single low reading is insufficient (Bhasin et al., 2018, Endocrine Society guidelines).
What does the video say about symptoms of low testosterone overlap heavily with depression, sleep apnea,?
Symptoms of low testosterone overlap heavily with depression, sleep apnea, obesity, and thyroid dysfunction. These must be excluded before attributing symptoms to hormonal decline.
What does the video say about trt?
TRT is a regulated medical treatment with documented risks including polycythemia, infertility, and potential cardiovascular effects. It requires clinical supervision, not self-diagnosis.
Sources & references
Citations extracted from our medical team's review. Click any citation to search PubMed.
Not medical advice. This video was made by 3 Hot Flushes, not by FormBlends. Our write-up above is an editorial review, not a medical recommendation. Talk to your doctor before making any decisions about medications or treatments.