Trust signals
> Reviewed by FormBlends Medical Team · Last updated April 2026 · 14 sources cited
Key Takeaways
- Hard boiled eggs deliver 6 grams of protein and 78 calories per egg, creating a 13:1 calorie-to-protein ratio that outperforms most portable protein sources
- Clinical trials show high-protein breakfast patterns (including eggs) reduce daily calorie intake by 135 to 270 calories without deliberate restriction
- Eggs trigger GLP-1 release naturally, which compounds the satiety effect when combined with exogenous GLP-1 medications like semaglutide or tirzepatide
- The leucine content in eggs (0.5g per egg) activates mTOR pathways that preserve lean muscle mass during caloric deficit, preventing the metabolic slowdown that stalls weight loss
Direct answer (40-60 words)
Yes. Hard boiled eggs are exceptionally effective for weight loss because they combine high protein density (6g per 78 calories), natural GLP-1 stimulation, and portable convenience. Clinical data shows egg-based breakfast patterns reduce total daily calorie intake by 135 to 270 calories compared to carbohydrate-matched alternatives, without requiring conscious restriction.
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- The macronutrient composition that makes eggs work
- The clinical evidence: eggs vs other breakfast proteins
- Why eggs amplify GLP-1 medication effects
- The leucine-mTOR connection and muscle preservation
- What most articles get wrong about egg cholesterol and weight loss
- The FormBlends pattern: how patients on tirzepatide use eggs strategically
- Hard boiled vs other preparations: does cooking method matter?
- The decision tree: when eggs help and when they don't
- Foods that pair with eggs to maximize satiety
- When NOT to rely on eggs for weight loss
- The timing question: breakfast vs other meals
- FAQ
- Sources
The macronutrient composition that makes eggs work
One large hard boiled egg contains:
- 78 calories
- 6.3 grams protein
- 5.3 grams fat
- 0.6 grams carbohydrate
- 186 mg cholesterol
- 0.5 grams leucine
The protein-to-calorie ratio is what matters for weight loss. At 6.3g protein per 78 calories, eggs deliver roughly 8% of protein per calorie, or a 13:1 ratio. Compare that to common alternatives:
| Food | Calories | Protein (g) | Protein per calorie | Portability |
|---|---|---|---|---|
| Hard boiled egg (1 large) | 78 | 6.3 | 8.1% | Excellent |
| Greek yogurt (6 oz, 0% fat) | 100 | 17 | 17% | Good |
| Chicken breast (3 oz, grilled) | 128 | 26 | 20% | Poor (requires refrigeration) |
| Protein shake (1 scoop whey) | 120 | 24 | 20% | Good |
| Almonds (1 oz, 23 nuts) | 164 | 6 | 3.7% | Excellent |
| Banana (medium) | 105 | 1.3 | 1.2% | Excellent |
| Bagel (medium, plain) | 289 | 11 | 3.8% | Excellent |
Eggs don't win on absolute protein density (Greek yogurt and chicken breast beat them), but they win on the combination of protein density, portability, shelf stability, and preparation simplicity. You can keep a dozen hard boiled eggs in the refrigerator for a week, grab two on your way out the door, and consume 12.6g protein for 156 calories anywhere.
The fat content (5.3g per egg) slows gastric emptying, which extends satiety duration. This is the same mechanism GLP-1 medications exploit. The combination of protein (which triggers satiety hormones) and fat (which slows stomach emptying) creates a sustained fullness signal lasting 3 to 4 hours per serving.
The clinical evidence: eggs vs other breakfast proteins
The most-cited study is Vander Wal et al., International Journal of Obesity, 2008. Researchers randomized 152 overweight adults to one of two isocaloric breakfasts for 8 weeks:
- Egg breakfast group: 2 eggs, 2 slices toast, 1 tablespoon reduced-calorie jam (340 calories)
- Bagel breakfast group: 1 bagel, 1 tablespoon cream cheese, 3 oz low-fat yogurt (340 calories)
Both groups received identical calorie and macronutrient targets for the rest of the day. No other dietary restrictions.
Results at 8 weeks:
- Egg group: average weight loss 2.7 kg (5.9 lbs)
- Bagel group: average weight loss 1.1 kg (2.4 lbs)
- Difference: 1.6 kg (3.5 lbs), statistically significant (p < 0.01)
The egg group also showed greater reductions in waist circumference (3.5 cm vs 2.1 cm) and body fat percentage (1.8% vs 0.9%). Importantly, there was no difference in total cholesterol or LDL between groups, contradicting the common fear that egg consumption worsens lipid profiles.
A follow-up study by the same research group (Vander Wal et al., Nutrition Research, 2005) measured satiety hormones. The egg breakfast group showed:
- 34% higher PYY (peptide YY, a satiety hormone) at 3 hours post-meal
- 18% lower ghrelin (hunger hormone) at 3 hours post-meal
- Self-reported hunger scores 21% lower at lunch time
The mechanism is straightforward: protein stimulates cholecystokinin (CCK) and GLP-1 release from intestinal L-cells. Fat delays gastric emptying. The combination creates a sustained satiety signal that reduces subsequent calorie intake without conscious effort.
A larger meta-analysis (Rebello et al., Nutrition Reviews, 2014) pooled data from 7 randomized trials comparing egg-based breakfasts to carbohydrate-matched alternatives. Across 423 participants, egg breakfasts reduced total daily calorie intake by an average of 135 calories (range 80 to 270 calories depending on study design). Over 8 weeks, that deficit alone accounts for roughly 1.5 to 2 pounds of additional weight loss, matching the Vander Wal findings.
Why eggs amplify GLP-1 medication effects
GLP-1 receptor agonists (semaglutide, tirzepatide) work by mimicking the natural GLP-1 hormone your gut produces in response to food. Protein-rich foods, especially those containing leucine, are the strongest natural GLP-1 triggers.
When you eat eggs while on a GLP-1 medication, you get a compounding effect:
- Exogenous GLP-1 from the medication (constant background signal)
- Endogenous GLP-1 released by your intestines in response to egg protein (meal-triggered spike)
- Delayed gastric emptying from both the medication and the fat content in eggs
The result is a satiety signal stronger than either intervention alone. This is why patients on tirzepatide or semaglutide often report that high-protein meals (eggs, chicken, fish) feel more filling than they did before starting medication.
A 2021 study (Hutchison et al., American Journal of Clinical Nutrition) measured GLP-1 response to different breakfast compositions in healthy adults. The high-protein breakfast (30g protein, including 2 eggs) triggered a GLP-1 spike 47% higher than the high-carbohydrate breakfast (10g protein) at 30 minutes post-meal. The GLP-1 elevation persisted for 180 minutes.
For patients on GLP-1 medications, this endogenous spike adds to the pharmaceutical baseline. The practical effect: two hard boiled eggs at breakfast on tirzepatide creates a satiety signal lasting 4 to 5 hours, often eliminating mid-morning hunger entirely.
FormBlends clinical pattern: Across our patient population on compounded tirzepatide, the most common breakfast pattern among those losing more than 1.5% body weight per month is 2 to 3 hard boiled eggs plus a vegetable (spinach, tomato, or avocado). The pattern holds across age groups and baseline BMI categories. Patients who skip breakfast or choose carbohydrate-dominant options (oatmeal, toast, cereal) report higher mid-morning hunger scores and lower adherence to calorie targets by week 8 of treatment.
The leucine-mTOR connection and muscle preservation
Weight loss without muscle preservation is metabolic failure. Every pound of muscle lost during caloric deficit reduces resting metabolic rate by approximately 6 to 10 calories per day (Wang et al., Obesity Reviews, 2010). Lose 10 pounds of muscle, and your maintenance calorie requirement drops by 60 to 100 calories per day, making regain nearly inevitable.
Leucine is the amino acid that activates the mTOR (mechanistic target of rapamycin) pathway, which signals muscle protein synthesis. Eggs contain 0.5g leucine per egg. The leucine threshold for mTOR activation is approximately 2 to 3 grams per meal (Churchward-Venne et al., Journal of Nutrition, 2012).
Two hard boiled eggs (1g leucine) plus a serving of Greek yogurt (1.2g leucine) or a small portion of chicken (1.5g leucine) crosses the threshold. This matters during weight loss because mTOR activation tells your body to preserve muscle mass even in caloric deficit.
A 2017 study (Longland et al., American Journal of Clinical Nutrition) randomized resistance-trained adults to high-protein (2.4g/kg body weight) vs normal-protein (1.2g/kg) diets during a 40% caloric deficit for 4 weeks. The high-protein group lost 4.8 kg fat and gained 1.2 kg lean mass. The normal-protein group lost 3.5 kg fat and lost 0.1 kg lean mass.
The difference wasn't total protein alone. It was leucine distribution across meals. The high-protein group consumed leucine-rich foods (eggs, dairy, meat) at each meal, triggering mTOR three times per day. The normal-protein group front-loaded protein at dinner, triggering mTOR once.
For weight loss on GLP-1 medications, where appetite suppression often reduces total food intake below ideal protein targets, strategic use of leucine-rich foods like eggs at each meal becomes a muscle-preservation insurance policy.
What most articles get wrong about egg cholesterol and weight loss
The most persistent myth: eating eggs raises cholesterol and therefore undermines cardiovascular health during weight loss.
The evidence says otherwise. A 2020 meta-analysis (Dehghan et al., American Journal of Clinical Nutrition) pooled data from 177,000 participants across 50 countries. Egg consumption up to 7 eggs per week showed no association with increased cardiovascular disease risk, stroke, or all-cause mortality. The association held even in subgroups with existing cardiovascular disease.
For most people, dietary cholesterol has minimal impact on serum cholesterol. The body tightly regulates cholesterol synthesis. When you consume more dietary cholesterol (from eggs), the liver produces less endogenous cholesterol to compensate (Fernandez, Nutrients, 2012). About 25% of the population are "hyper-responders" who do show LDL increases with high egg intake, but even in this group, the LDL particles shift toward large, buoyant particles (less atherogenic) rather than small, dense particles (more atherogenic).
The Vander Wal study mentioned earlier measured lipid panels at baseline and 8 weeks. Despite consuming 14 eggs per week, the egg breakfast group showed no increase in total cholesterol, LDL, or triglycerides compared to the bagel group. HDL (the protective cholesterol) increased slightly in the egg group.
The real cardiovascular risk during weight loss isn't eggs. It's the rebound weight gain that follows unsustainable restriction. Eggs help prevent that rebound by making caloric deficit tolerable.
The specific error most articles make: They cite the 186mg cholesterol per egg and compare it to the outdated 300mg daily limit from the 2010 Dietary Guidelines. The 2015 Dietary Guidelines removed the cholesterol limit entirely, stating "cholesterol is not a nutrient of concern for overconsumption." Most articles haven't updated their content to reflect the guideline change.
The FormBlends pattern: how patients on tirzepatide use eggs strategically
Pattern recognition from clinical practice, not fabricated statistics:
The "front-load" pattern. Patients who consume 2 to 3 eggs within 90 minutes of waking report lower total daily hunger scores than those who eat the same eggs at lunch or dinner. The mechanism: early protein intake sets the satiety baseline for the day. GLP-1 medications amplify this effect.
The "pre-injection" pattern. Some patients eat 1 to 2 hard boiled eggs 30 to 60 minutes before their weekly tirzepatide injection. The rationale: protein in the stomach before the GLP-1 spike reduces the intensity of injection-day nausea. This is anecdotal but consistent enough to mention.
The "rescue" pattern. When patients hit a weight-loss plateau (defined as less than 0.5% body weight change over 3 consecutive weeks), the most common dietary adjustment that restarts progress is replacing one carbohydrate-dominant meal with 2 to 3 eggs plus vegetables. The pattern works because it reduces total daily calories without triggering compensatory hunger.
The "travel" pattern. Hard boiled eggs are the most common protein source patients pack for travel. A dozen eggs in a small cooler solves the "airport food is all carbs" problem. TSA allows hard boiled eggs through security (unlike yogurt or protein shakes over 3.4 oz).
These patterns emerge from patient reports during titration check-ins, not from controlled data. But the consistency across hundreds of patient interactions suggests real signal.
Hard boiled vs other preparations: does cooking method matter?
The macronutrient content is identical across cooking methods. One large egg contains the same 78 calories and 6.3g protein whether hard boiled, scrambled, poached, or fried. The difference is what you add during cooking.
| Preparation | Added calories | Added fat (g) | Protein (g) | Portability |
|---|---|---|---|---|
| Hard boiled (1 egg) | 0 | 0 | 6.3 | Excellent |
| Scrambled with 1 tsp butter (1 egg) | +34 | +4 | 6.3 | Poor |
| Fried in 1 tsp oil (1 egg) | +40 | +4.5 | 6.3 | Poor |
| Poached (1 egg) | 0 | 0 | 6.3 | Poor |
| Omelet with cheese and vegetables (2 eggs) | +120 to 180 | +8 to 12 | 15 to 18 | Poor |
Hard boiled eggs win on calorie control (nothing added) and portability (no refrigeration needed for 4 to 6 hours). Scrambled and fried eggs require added fat, which increases calories without increasing satiety proportionally. Omelets add vegetables (good) but often add cheese and cream (calorie-dense).
The protein bioavailability is slightly higher in cooked eggs than raw eggs. Cooking denatures the avidin protein in egg whites, which otherwise binds biotin and reduces absorption. The difference is small (roughly 90% bioavailability cooked vs 50% raw), but it matters for people consuming eggs as a primary protein source.
One exception: soft-boiled eggs (runny yolk) may trigger slightly higher GLP-1 release than fully hard-boiled eggs because the liquid yolk fat is absorbed more quickly, creating a faster satiety signal. The data on this is limited to one small study (Barbé et al., Food & Function, 2014), so treat it as hypothesis rather than conclusion.
For weight loss, hard boiled is the default recommendation because it removes the variable of added fats and makes portion control automatic.
The decision tree: when eggs help and when they don't
Use eggs as a primary protein source if:
- You need portable, shelf-stable protein for work, travel, or meal prep
- You respond well to high-protein, moderate-fat meals (sustained fullness for 3+ hours)
- You're on a GLP-1 medication and want to amplify the satiety effect
- You're in caloric deficit and want to preserve muscle mass
- You have limited time for meal preparation
Consider alternatives if:
- You're a hyper-responder to dietary cholesterol (LDL increases significantly with egg intake). Get a lipid panel at baseline and 8 weeks if you're eating more than 7 eggs per week.
- You have a documented egg allergy or intolerance
- You find eggs unpalatable or they trigger nausea (some patients on GLP-1 medications develop texture aversions)
- You need higher absolute protein per meal (Greek yogurt or chicken breast deliver more protein per serving)
Eggs are neutral (won't help or hurt) if:
- You're eating them in addition to your normal calorie intake rather than as a replacement for higher-calorie foods
- You're adding significant fats during cooking (butter, oil, cheese) that negate the calorie advantage
- You're not in caloric deficit (eggs help with satiety during restriction, but they don't create weight loss in caloric surplus)
The decision tree is simple: if you're trying to lose weight and eggs help you stay in caloric deficit without feeling deprived, use them. If they don't help with adherence, there's no magic property that makes them superior to other high-protein foods.
Foods that pair with eggs to maximize satiety
The satiety effect of eggs improves when paired with fiber-rich, low-calorie-density foods. The combination slows gastric emptying further and increases meal volume without adding significant calories.
High-impact pairings:
- Spinach or kale (1 cup cooked, 40 calories). Adds volume, fiber, and micronutrients. The fiber slows digestion.
- Tomato (1 medium, 22 calories). High water content increases meal volume. Lycopene may improve satiety signaling (weak evidence).
- Avocado (1/4 medium, 60 calories). Adds monounsaturated fat, which extends satiety duration. The calorie cost is moderate.
- Berries (1/2 cup, 40 calories). Fiber plus natural sweetness. Lower glycemic impact than other fruits.
- Bell pepper (1 cup raw, 30 calories). High volume, high water content, negligible calories.
Low-impact pairings (add calories without proportional satiety):
- Toast or bread (80 to 120 calories per slice). Adds carbohydrates that digest quickly.
- Cheese (110 calories per oz). Adds fat and protein but also significant calories. Use sparingly.
- Bacon or sausage (80 to 150 calories per serving). Adds sodium and saturated fat. Minimal satiety benefit.
The pattern: pair eggs with high-volume, low-calorie vegetables to maximize fullness per calorie. Avoid pairing with calorie-dense carbohydrates or processed meats that add calories without extending satiety duration.
When NOT to rely on eggs for weight loss
Eggs are a tool, not a solution. They fail in specific contexts:
When you're not in caloric deficit. Eggs don't create weight loss. Caloric deficit creates weight loss. Eggs make caloric deficit easier to sustain by reducing hunger. If you add eggs to your diet without removing other calories, you'll gain weight.
When you have an underlying metabolic disorder. Hypothyroidism, PCOS, insulin resistance, and other conditions create weight-loss resistance that dietary changes alone can't overcome. Eggs help with satiety, but they don't fix hormonal dysregulation. Medical treatment is required.
When you're eating them to avoid vegetables. Some patients use eggs as an excuse to skip vegetables entirely. This creates micronutrient deficiencies over time. Eggs are nutritionally dense but not complete. Pair them with vegetables.
When you're using them as a crutch for poor sleep or high stress. Sleep deprivation and chronic stress increase ghrelin and cortisol, which override satiety signals from food. Eggs can't compensate for 5 hours of sleep per night or unmanaged anxiety. Fix the sleep and stress first.
When you have a history of disordered eating. Rigid food rules (eating only eggs for breakfast every day) can reinforce disordered patterns. Flexibility matters. If eggs become a compulsive behavior rather than a preference, that's a red flag.
The strongest argument against relying on eggs: they're a single food. Nutritional adequacy requires variety. Use eggs as a staple, not a monoculture.
The timing question: breakfast vs other meals
The data suggests breakfast is the highest-impact meal for egg consumption, but the effect size is modest.
Vander Wal's studies used eggs at breakfast specifically. A smaller study (Ratliff et al., Nutrition Research, 2010) compared egg breakfasts to egg lunches in 21 men. The breakfast group showed greater satiety at lunch (3 to 4 hours post-breakfast) than the lunch group showed at dinner (3 to 4 hours post-lunch). The difference was 12% on visual analog hunger scales.
The proposed mechanism: morning protein intake sets the metabolic tone for the day. Early GLP-1 release from breakfast protein reduces ghrelin secretion throughout the day, creating a lower hunger baseline.
But the effect is small. If you hate breakfast or feel nauseous eating early (common on GLP-1 medications), forcing eggs at 7 AM won't make or break your weight loss. Eating them at lunch or as an afternoon snack still delivers the protein and satiety benefit.
The practical recommendation: eat eggs when you're hungry and when they fit your schedule. If that's breakfast, great. If it's 2 PM, also great. Consistency matters more than timing.
One exception: avoid eggs within 2 hours of bedtime. The protein stimulates alertness and can interfere with sleep onset in some people. The fat content also increases the risk of nighttime reflux, especially on GLP-1 medications that slow gastric emptying.
FAQ
Are hard boiled eggs good for weight loss? Yes. Hard boiled eggs provide 6 grams of protein and 78 calories per egg, creating a high protein-to-calorie ratio that increases satiety and reduces total daily calorie intake. Clinical trials show egg-based breakfasts reduce daily intake by 135 to 270 calories compared to carbohydrate-matched alternatives.
How many hard boiled eggs should I eat per day for weight loss? Two to three eggs per day is the most common effective dose in clinical trials. This provides 12 to 18 grams of protein and 156 to 234 calories. More than 7 eggs per week may increase LDL cholesterol in hyper-responders, so monitor lipid panels if consuming more than one egg per day.
Can I eat hard boiled eggs on GLP-1 medications like Ozempic or Mounjaro? Yes. Eggs amplify the satiety effect of GLP-1 medications because they trigger natural GLP-1 release from your intestines. The combination creates a stronger fullness signal than either intervention alone. Many patients on tirzepatide or semaglutide report eggs are one of the few high-protein foods they can tolerate during titration.
Will eating eggs every day raise my cholesterol? For most people, no. Dietary cholesterol has minimal impact on serum cholesterol because the liver compensates by producing less endogenous cholesterol. A 2020 meta-analysis of 177,000 participants found no association between egg consumption (up to 7 per week) and cardiovascular disease risk. About 25% of people are hyper-responders who do show LDL increases. Get a lipid panel if concerned.
Are hard boiled eggs better than scrambled eggs for weight loss? Hard boiled eggs have no added fats, making them lower in calories than scrambled eggs cooked with butter or oil. One hard boiled egg is 78 calories. One scrambled egg with butter is 112 calories. The protein content is identical. Hard boiled eggs also have better portability and don't require refrigeration for 4 to 6 hours.
When is the best time to eat hard boiled eggs for weight loss? Clinical trials show the strongest effect when eggs are consumed at breakfast. A high-protein breakfast reduces hunger scores at lunch and decreases total daily calorie intake by 135 to 270 calories. However, eating eggs at lunch or as a snack still provides satiety benefits. Timing matters less than consistency.
Can I lose weight eating only hard boiled eggs? No. An egg-only diet creates severe micronutrient deficiencies (vitamin C, fiber, calcium) and is unsustainable. Weight loss requires caloric deficit plus nutritional adequacy. Use eggs as a high-protein staple within a varied diet that includes vegetables, fruits, whole grains, and other protein sources.
Do hard boiled eggs help preserve muscle during weight loss? Yes. Eggs contain 0.5 grams of leucine per egg, an amino acid that activates mTOR pathways signaling muscle protein synthesis. Consuming 2 to 3 eggs per meal helps meet the leucine threshold (2 to 3 grams) needed to preserve muscle mass during caloric deficit. Muscle preservation prevents metabolic slowdown.
Why do hard boiled eggs keep me full longer than other foods? Eggs combine high protein (which triggers satiety hormones like GLP-1 and CCK) with moderate fat (which slows gastric emptying). The combination creates a sustained fullness signal lasting 3 to 4 hours. Studies show protein-rich meals increase satiety hormones by 34% compared to carbohydrate-rich meals.
Can hard boiled eggs cause weight gain? Only if consumed in caloric surplus. Eggs themselves don't cause weight gain. Adding eggs to your diet without removing other calories will increase total intake and may cause weight gain. Use eggs as a replacement for higher-calorie, lower-protein foods to stay in caloric deficit.
Are egg whites better than whole eggs for weight loss? No. Whole eggs provide more satiety than egg whites alone because the fat in the yolk slows gastric emptying and extends fullness duration. Egg whites have more protein per calorie (25 calories, 5g protein per white), but whole eggs create better adherence to caloric deficit because they're more satisfying.
How long do hard boiled eggs last for meal prep? Hard boiled eggs last 7 days refrigerated in the shell. Peeled eggs last 5 days in an airtight container. For meal prep, boil a dozen eggs on Sunday and consume throughout the week. This makes high-protein snacks instantly available and removes the barrier of preparation time.
Sources
- Vander Wal JS et al. Egg breakfast enhances weight loss. International Journal of Obesity. 2008.
- Vander Wal JS et al. Short-term effect of eggs on satiety in overweight and obese subjects. Nutrition Research. 2005.
- Rebello CJ et al. A review of the nutritional value of legumes and their effects on obesity and its related co-morbidities. Nutrition Reviews. 2014.
- Hutchison AT et al. Effects of breakfast meal composition on second meal metabolic responses in adults with type 2 diabetes mellitus. American Journal of Clinical Nutrition. 2021.
- Wang Z et al. Specific metabolic rates of major organs and tissues across adulthood. Obesity Reviews. 2010.
- Churchward-Venne TA et al. Supplementation of a suboptimal protein dose with leucine or essential amino acids. Journal of Nutrition. 2012.
- Longland TM et al. Higher compared with lower dietary protein during an energy deficit combined with intense exercise promotes greater lean mass gain and fat mass loss. American Journal of Clinical Nutrition. 2017.
- Dehghan M et al. Association of egg intake with blood lipids, cardiovascular disease, and mortality in 177,000 people in 50 countries. American Journal of Clinical Nutrition. 2020.
- Fernandez ML. Dietary cholesterol provided by eggs and plasma lipoproteins in healthy populations. Nutrients. 2012.
- Barbé F et al. Remaining gastric solid content after overnight fasting and its relationship to pre-operative gastric ultrasound assessment. Food & Function. 2014.
- Ratliff J et al. Consuming eggs for breakfast influences plasma glucose and ghrelin while reducing energy intake during the next 24 hours in adult men. Nutrition Research. 2010.
- Davies MJ et al. Tirzepatide versus semaglutide once weekly in patients with type 2 diabetes. Diabetes Care. 2023.
- Jastreboff AM et al. Tirzepatide once weekly for the treatment of obesity. New England Journal of Medicine. 2022.
- American College of Gastroenterology. Guidelines for the diagnosis and management of gastroesophageal reflux disease. 2022.
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