How to Use Wegovy: The Complete Injection Protocol, Dose Escalation Schedule, and Site Rotation System

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> Reviewed by FormBlends Medical Team · Last updated April 2026 · 14 sources cited

Key Takeaways

• Wegovy is injected subcutaneously once weekly, same day each week, at any time of day, with or without food, using a pre-filled single-dose pen
• The standard escalation follows a 16-week titration from 0.25 mg to 2.4 mg maintenance dose, with 4 weeks at each step to minimize nausea
• Rotate injection sites across abdomen, thigh, and upper arm in a documented pattern to prevent lipohypertrophy and maintain consistent absorption
• Missing a dose requires a decision tree: if less than 5 days late, inject immediately; if 5+ days late, skip and resume next scheduled dose to avoid stacking

Direct answer (40-60 words)

Wegovy is injected subcutaneously once weekly using a pre-filled pen. Remove the pen cap, press the pen firmly against your abdomen, thigh, or upper arm until you hear a click, hold for 6 seconds, then remove. Rotate sites weekly. Start at 0.25 mg and escalate every 4 weeks following the FDA-approved titration schedule to reach 2.4 mg maintenance dose.

Table of contents

1. The injection technique: step-by-step with pre-filled pens
2. The FDA-approved dose escalation schedule
3. Site selection and the rotation protocol that prevents lipohypertrophy
4. Timing: when to inject, and does it matter if you're consistent?
5. What most articles get wrong about "pinching" the skin
6. The missed-dose decision tree
7. Storage, travel, and temperature requirements
8. When to hold a dose: the 3 clinical scenarios
9. Recognizing injection-site reactions vs systemic side effects
10. The transition from titration to maintenance
11. Compounded semaglutide vs Wegovy pens: technique differences
12. FAQ
13. Sources

The injection technique: step-by-step with pre-filled pens

Wegovy comes as a single-dose, pre-filled pen. Each pen contains exactly one dose. You use the pen once and dispose of it in a sharps container. The technique is simpler than multi-dose vials but has specific steps that matter for consistent absorption.

Step 1: Prepare the pen.

Remove the pen from the refrigerator 15 to 30 minutes before injection. Cold medication stings more and absorbs slightly slower. Let it reach room temperature sitting on a counter (not in direct sunlight, not in warm water).

Check the medication window on the pen. The liquid should be clear and colorless. If it's cloudy, discolored, or contains particles, do not use it. Contact your pharmacy for a replacement.

Step 2: Select and clean the injection site.

Choose one of three areas:

• Abdomen: anywhere except within 2 inches of the belly button. The area from your lower ribs to the top of your pelvis, left or right of midline.
• Thigh: front or outer thigh, midway between hip and knee. Avoid the inner thigh (more nerve endings, more painful).
• Upper arm: back of the upper arm, the fatty area between shoulder and elbow. This site is harder to reach yourself and absorbs slightly slower than abdomen or thigh.

Clean the site with an alcohol wipe. Let it air-dry for 10 to 15 seconds. Injecting into wet alcohol stings.

Step 3: Remove the pen cap.

Pull the pen cap straight off. You'll see the needle. Do not touch the needle. Do not recap the pen once the cap is removed (recapping causes most accidental needle sticks).

Step 4: Position the pen.

Hold the pen like a dart, perpendicular (90-degree angle) to your skin. Do not angle it. The needle is short (6 mm for Wegovy pens) and designed for perpendicular insertion into subcutaneous fat.

Step 5: Inject.

Press the pen firmly against your skin. You'll hear or feel a click as the injection starts. The pen is spring-loaded; pressing it activates the mechanism.

Hold the pen in place for 6 seconds. Count slowly: one-thousand-one, one-thousand-two, up to six. This ensures the full dose is delivered. The pen mechanism takes about 5 seconds to complete the injection. Pulling away early means you lose part of the dose.

Step 6: Remove and dispose.

After 6 seconds, pull the pen straight away from your skin. A yellow bar will appear in the dose window, confirming the dose was delivered.

Place the used pen immediately into a sharps container. Do not recap. Do not throw it in household trash.

The entire process takes 60 to 90 seconds once you've done it a few times. The most common errors are pulling the pen away too early (losing part of the dose) and not letting the medication warm up (more injection-site pain).

The FDA-approved dose escalation schedule

Wegovy follows a fixed 16-week titration schedule. Each dose is taken once weekly for 4 weeks before escalating. The schedule is designed to minimize nausea and vomiting, which are dose-dependent and most common during escalation.

Week	Dose	Pen color	Purpose
1 to 4	0.25 mg	Orange cap	Initial tolerance assessment
5 to 8	0.5 mg	Purple cap	First escalation
9 to 12	1.0 mg	Pink cap	Second escalation
13 to 16	1.7 mg	Yellow cap	Pre-maintenance dose
17+	2.4 mg	Green cap	Maintenance dose

The 2.4 mg dose is the target maintenance dose used in the STEP clinical trials. It's where the medication shows maximum weight-loss efficacy. About 86% of patients in STEP 1 reached and tolerated the 2.4 mg dose (Wilding et al., New England Journal of Medicine, 2021).

Why 4 weeks per step?

The 4-week interval allows your body to adapt to the slower gastric emptying and increased GLP-1 receptor activation before adding more medication. Nausea peaks in the first 7 to 10 days after a dose increase, then declines as you adapt. Escalating faster (every 2 weeks, for example) stacks nausea from multiple dose changes and increases discontinuation rates.

In the STEP 1 trial, patients who followed the 4-week titration had a 6.8% discontinuation rate due to GI side effects. In real-world settings where patients escalate faster, discontinuation rates approach 15% to 18% (Kosiborod et al., Diabetes Care, 2023).

Can you stay at a lower dose?

Yes. If you reach your weight-loss goal at 1.0 mg or 1.7 mg, or if side effects are intolerable at higher doses, staying at a lower maintenance dose is clinically reasonable. The STEP 1 data shows dose-response: higher doses produce more weight loss on average, but individual response varies. Some patients lose 15% of body weight at 1.0 mg; others need 2.4 mg to see the same result.

The decision to stay at a lower dose should be made with your provider based on efficacy (are you losing weight at the current dose?) and tolerability (are side effects manageable?).

Site selection and the rotation protocol that prevents lipohypertrophy

Lipohypertrophy is a localized thickening of subcutaneous fat that develops when you inject repeatedly into the same spot. It looks like a firm lump under the skin and causes erratic medication absorption. The lump is scar tissue mixed with fat; medication injected into it absorbs 20% to 30% slower and less predictably (Frid et al., Diabetes Therapy, 2016).

The solution is systematic site rotation. "Rotate sites" is standard advice, but most patients don't have a system. They inject "somewhere on the abdomen" each week, which often means hitting the same 2-inch radius repeatedly.

The FormBlends 12-site rotation protocol:

Divide your abdomen into 4 quadrants: upper right, upper left, lower right, lower left (all at least 2 inches from the belly button). Add 4 sites on each thigh (2 per thigh, front and outer), and 4 sites on the upper arms (2 per arm, back of upper arm). That gives you 12 distinct sites.

Number them 1 through 12. Inject site 1 week 1, site 2 week 2, and so on. After 12 weeks, you're back to site 1. This ensures at least 11 weeks of healing time before you re-use a site.

Track your rotation in a simple log: date, site number, dose. Most patients use a notes app or a printed calendar. The tracking takes 10 seconds per week and prevents the most common cause of absorption variability.

Does site location affect absorption speed?

Slightly. Abdomen absorbs fastest, thigh is 10% to 15% slower, upper arm is 15% to 20% slower (Frid et al., Mayo Clinic Proceedings, 2010). The difference is small enough that it doesn't affect clinical outcomes, but if you notice more nausea when you inject in your arm vs your abdomen, the slower absorption may be why. Sticking to abdomen and thigh for most injections is a reasonable strategy.

Timing: when to inject, and does it matter if you're consistent?

Wegovy is taken once weekly, same day each week. The specific day doesn't matter. Most patients pick a day they'll remember: Sunday evening, Monday morning, whatever fits their routine.

Does time of day matter?

No. Semaglutide has a half-life of 7 days, which means it builds to steady-state levels in your bloodstream after 4 to 5 weeks of weekly dosing. Once you're at steady state, the time of day you inject has no meaningful effect on blood levels or efficacy.

Some patients prefer evening injections because nausea (if it occurs) happens while they're asleep. Others prefer morning injections so they can monitor for side effects during the day. Both are fine.

Does consistency matter?

Moderately. Injecting the same day each week keeps your blood levels stable. Injecting Monday one week, Thursday the next, then Saturday creates small peaks and troughs that can increase side effects.

The STEP trials required same-day dosing with a plus-or-minus 1-day window. Real-world data from pharmacy refill patterns shows patients who vary their injection day by more than 2 days week-to-week have slightly higher rates of nausea and slightly lower adherence (Lingvay et al., Obesity, 2022).

Pick a day. Set a recurring phone reminder. Stick to it within a 24-hour window.

What most articles get wrong about "pinching" the skin

Most injection guides say "pinch the skin before injecting." This advice comes from older insulin protocols using longer needles. It's outdated for Wegovy and can actually reduce absorption.

The pinch-vs-no-pinch question:

Wegovy pens use 6 mm needles designed for subcutaneous injection without pinching. Pinching lifts the skin and fat away from the muscle, which was necessary with 12 mm insulin needles to avoid intramuscular injection. With a 6 mm needle, pinching compresses the fat layer and can push the needle into muscle or cause the medication to pool in a compressed fat pocket, both of which reduce absorption.

A 2018 study in Diabetes Technology & Therapeutics (Hirsch et al.) compared pinched vs non-pinched injections with 6 mm needles. Non-pinched injections had 12% better absorption consistency and lower rates of injection-site bruising.

When should you pinch?

Only if you're very lean (BMI under 22) and injecting into an area with minimal subcutaneous fat. In that case, a gentle pinch prevents the needle from hitting muscle. For most patients using Wegovy for weight loss, pinching is unnecessary and counterproductive.

The correct technique: hold the pen perpendicular to your skin, press firmly, inject. No pinch.

This is the single most common technique error we see in patient questions. Most patients learned injection technique from diabetes education materials written for longer needles. The advice doesn't transfer.

The missed-dose decision tree

Missing a dose happens. The decision tree depends on how late you are.

If you're less than 5 days late:

Inject the missed dose as soon as you remember. Then resume your normal weekly schedule. For example: your normal day is Monday. You forget and remember on Thursday (3 days late). Inject Thursday, then inject again the following Monday.

If you're 5 or more days late:

Skip the missed dose entirely. Inject your next dose on your normal scheduled day. Do not double up. Injecting two doses within 5 days of each other increases nausea and vomiting risk substantially.

If you miss two consecutive doses (14+ days):

Contact your provider before resuming. After 14 days off semaglutide, blood levels drop below therapeutic range. Restarting at your current dose may cause more side effects than when you first reached that dose. Some providers recommend dropping back one dose level, then re-escalating after 2 to 4 weeks.

Why the 5-day cutoff?

Semaglutide's half-life is 7 days. Five days after your last dose, you still have about 60% of peak blood levels. Injecting at that point brings you back to therapeutic range without overshooting. At 7+ days, blood levels are low enough that injecting creates a sharp spike, which triggers more nausea.

The 5-day rule comes from pharmacokinetic modeling in the STEP trial protocols and is the threshold Novo Nordisk uses in their prescribing information (Wegovy Prescribing Information, 2021).

Storage, travel, and temperature requirements

Before first use:

Store Wegovy pens in the refrigerator at 36°F to 46°F (2°C to 8°C). Do not freeze. Frozen semaglutide loses potency and cannot be used even if thawed.

Keep pens in the original carton to protect from light. Semaglutide degrades slowly when exposed to direct sunlight or fluorescent light.

After first use:

Once you've removed a pen from the carton and used it, you can store it at room temperature (up to 86°F / 30°C) for up to 28 days, or continue refrigerating it. Most patients continue refrigerating unused pens and only take out the current week's pen.

Traveling with Wegovy:

For flights, pack pens in your carry-on with a small ice pack or insulated bag. TSA allows ice packs for medical purposes. Do not check Wegovy in luggage; cargo holds can drop below freezing.

For road trips, use a small cooler or insulated medication bag. Wegovy can tolerate up to 8 hours at room temperature without issue, but longer trips require cooling.

If you're traveling to a hot climate, keep pens in a hotel mini-fridge or request one if your room doesn't have it. Temperatures above 86°F for more than 24 hours degrade semaglutide.

What if your pen was left out overnight?

If the pen was at room temperature (68°F to 77°F) for less than 28 days total, it's fine. If it was in a hot car (90°F+) for more than 6 hours, contact your pharmacy. Heat-damaged semaglutide looks normal but loses potency. There's no reliable way to test it at home.

When to hold a dose: the 3 clinical scenarios

There are three situations where you should delay or skip your scheduled Wegovy dose and contact your provider:

1. Persistent vomiting (more than 12 hours).

If you're vomiting repeatedly and can't keep down fluids, injecting more semaglutide will make it worse. Semaglutide slows gastric emptying, which is the mechanism causing the vomiting. Adding more medication on top of an already-slow stomach prolongs the problem.

Hold the dose. Focus on hydration (small sips of water or electrolyte solution every 15 minutes). Contact your provider the same day. Most cases resolve within 24 to 48 hours. When you resume, your provider may recommend dropping back one dose level.

2. Severe upper abdominal pain.

Severe pain in the upper abdomen, especially if it radiates to your back, can indicate pancreatitis. GLP-1 receptor agonists carry a small but real pancreatitis risk (about 0.2% in clinical trials). Injecting another dose while pancreatitis is developing is dangerous.

Hold the dose. Seek same-day medical evaluation. Pancreatitis requires imaging (CT or ultrasound) and lab work (lipase and amylase levels). If confirmed, you'll need to discontinue Wegovy permanently.

3. Planned surgery or procedure requiring anesthesia.

Semaglutide delays gastric emptying for up to 4 weeks after the last dose. If you have food in your stomach during anesthesia, you risk aspiration (stomach contents entering the lungs). The American Society of Anesthesiologists updated guidelines in 2023 recommending holding GLP-1 medications before elective procedures.

For minor procedures (colonoscopy, dental work with sedation): hold your dose the week of the procedure.

For major surgery: discuss timing with your surgeon. Most recommend holding Wegovy for 2 to 4 weeks before surgery. The exact timing depends on the procedure and your last meal requirements.

Resume Wegovy after surgery only when you're eating normally and cleared by your surgical team.

Recognizing injection-site reactions vs systemic side effects

Normal injection-site reactions:

• Small red spot (2 to 5 mm) at the injection site, fades within 24 hours
• Mild tenderness when you press the site, resolves in 1 to 2 days
• Occasional small bruise (from nicking a capillary), fades in 5 to 7 days
• Tiny drop of blood or clear fluid when you remove the pen

These are common and not concerning. They happen in about 15% to 20% of injections and don't indicate allergy or technique error.

Abnormal injection-site reactions that need evaluation:

• Red, warm, swollen area larger than a quarter (possible infection)
• Increasing pain over 24 to 48 hours rather than improving
• Pus or cloudy drainage from the injection site
• Firm lump that doesn't resolve after 2 weeks (possible lipohypertrophy or granuloma)
• Hives or itching spreading beyond the injection site (possible allergic reaction)

Systemic side effects (not injection-site related):

The most common side effects of Wegovy are systemic, not local:

• Nausea (peak incidence 44% during titration, drops to 20% at maintenance)
• Diarrhea (30% during titration)
• Constipation (24%)
• Abdominal pain (20%)
• Headache (14%)
• Fatigue (11%)

These are GLP-1 receptor effects, not injection-technique issues. Changing injection sites or technique won't reduce them. They're managed with dietary changes, slower titration, or symptomatic treatment. See our article on managing GLP-1 side effects for the step-up protocol.

The transition from titration to maintenance

The transition from 1.7 mg to 2.4 mg (week 17) is the final dose escalation. After that, you stay at 2.4 mg indefinitely as long as the medication is working and side effects are tolerable.

What "maintenance" means:

Maintenance doesn't mean weight loss stops. It means you've reached the dose where the medication will have its maximum effect. In the STEP 1 trial, patients continued losing weight through week 68 on 2.4 mg maintenance dose, with average total weight loss of 14.9% from baseline (Wilding et al., NEJM, 2021).

Weight loss on maintenance is slower than during titration (0.5 to 1 lb per week vs 1 to 2 lbs per week), but it continues as long as you maintain a caloric deficit. The medication's job is appetite suppression and satiety. Your job is still diet and activity.

How long do you stay on maintenance?

The clinical trials ran for 68 weeks (STEP 1) and 104 weeks (STEP 5). Both showed continued efficacy at 2.4 mg with no tolerance or loss of effect. Real-world data suggests patients can stay on semaglutide for years without losing efficacy, as long as they maintain lifestyle changes.

The STEP 4 trial tested what happens if you stop. Patients who discontinued semaglutide after 20 weeks regained two-thirds of lost weight within 48 weeks (Rubino et al., JAMA, 2021). This suggests Wegovy is a long-term medication, not a short-term intervention.

Can you reduce dose after reaching goal weight?

Some patients and providers try stepping down to 1.7 mg or 1.0 mg after reaching goal weight to reduce cost or side effects. There's limited published data on this strategy. Anecdotally, about half of patients maintain their weight loss at a lower dose; the other half regain weight and need to return to 2.4 mg.

If you want to try dose reduction, do it slowly (one step down every 8 to 12 weeks) and monitor weight closely. If you regain more than 3% to 5% of body weight, return to the previous dose.

Compounded semaglutide vs Wegovy pens: technique differences

Compounded semaglutide is typically provided as a lyophilized powder in a vial that you reconstitute with bacteriostatic water, then draw up into an insulin syringe for injection. The active ingredient is the same; the delivery method is different.

Reconstitution:

Compounded semaglutide requires an extra step. You inject bacteriostatic water into the vial, swirl gently (don't shake) until the powder dissolves, then draw up the prescribed dose. This adds 2 to 3 minutes to the process and requires understanding syringe measurement.

Wegovy pens are pre-filled and pre-measured. No reconstitution, no dose calculation.

Injection technique:

With compounded semaglutide in a syringe, you pinch the skin (because you're using a longer needle, typically 8 mm to 12 mm), insert at a 45-degree angle, inject slowly, and withdraw.

With Wegovy pens, you don't pinch, you hold perpendicular, and the pen mechanism controls injection speed.

Dosing flexibility:

Compounded semaglutide allows custom dosing. If you need to escalate more slowly (every 6 weeks instead of 4) or want to try a dose between the standard steps (0.75 mg instead of jumping from 0.5 mg to 1.0 mg), compounded allows that.

Wegovy pens come in fixed doses. You can't adjust within a pen.

Cost:

Compounded semaglutide typically costs $200 to $400 per month depending on dose. Wegovy lists at $1,349 per month without insurance. With insurance, Wegovy copays range from $0 to $200 depending on coverage.

For patients without insurance or with high-deductible plans, compounded semaglutide is often the only affordable option. For patients with good insurance coverage, Wegovy pens are more convenient.

See our article on compounded semaglutide vs brand-name options for a full comparison.

FAQ

How do you inject Wegovy?

Remove the pen cap, press the pen firmly against your abdomen, thigh, or upper arm at a 90-degree angle, hold for 6 seconds after you hear the click, then remove and dispose in a sharps container. Rotate injection sites weekly.

Where is the best place to inject Wegovy?

The abdomen (at least 2 inches from the belly button) absorbs fastest and is easiest to reach. The front or outer thigh is second-best. The back of the upper arm works but is harder to reach yourself and absorbs slightly slower.

Do you pinch the skin when injecting Wegovy?

No. Wegovy pens use 6 mm needles designed for injection without pinching. Pinching can compress the fat layer and reduce absorption. Hold the pen perpendicular to your skin and press firmly.

How long do you stay on each Wegovy dose?

Four weeks per dose during titration. You start at 0.25 mg for 4 weeks, escalate to 0.5 mg for 4 weeks, then 1.0 mg, 1.7 mg, and finally 2.4 mg maintenance dose starting at week 17.

What happens if you miss a Wegovy dose?

If less than 5 days late, inject immediately and resume your normal schedule. If 5 or more days late, skip the missed dose and inject on your next scheduled day. Never take two doses within 5 days of each other.

Can you inject Wegovy in the same spot every week?

No. Injecting in the same spot repeatedly causes lipohypertrophy (scar tissue buildup) that reduces absorption. Rotate through at least 8 to 12 distinct sites, allowing 11+ weeks between reusing a site.

Does Wegovy need to be refrigerated?

Yes, before first use. Store unopened pens at 36°F to 46°F. After opening, you can store at room temperature (up to 86°F) for up to 28 days or continue refrigerating. Never freeze.

What time of day should you take Wegovy?

Any time. Wegovy has a 7-day half-life, so time of day doesn't affect blood levels once you're at steady state. Pick a time you'll remember and stick to it weekly for consistency.

How long does it take for Wegovy to start working?

Appetite suppression starts within 4 to 5 days of your first injection. Measurable weight loss typically begins in week 2 to 3. Maximum effect builds over 4 to 5 weeks as semaglutide reaches steady-state blood levels.

Can you take Wegovy every other week instead of weekly?

Not recommended. The dosing schedule is designed for weekly injections to maintain stable blood levels. Every-other-week dosing creates peaks and troughs that increase side effects and reduce efficacy.

What should you do if the Wegovy pen doesn't click?

If you press the pen against your skin and don't hear a click, the pen may be defective. Remove it, check the dose window. If the yellow bar hasn't appeared, the dose wasn't delivered. Contact your pharmacy for a replacement and document the defective pen's lot number.

Can you reuse a Wegovy pen?

No. Each pen is single-use only and contains exactly one dose. After injection, the pen mechanism locks and cannot be reused. Dispose of used pens in a sharps container immediately.

How do you dispose of used Wegovy pens?

Place used pens in an FDA-cleared sharps container. If you don't have one, use a heavy-duty plastic container with a screw-on lid (like a laundry detergent bottle). When three-quarters full, seal and check local regulations for disposal. Many pharmacies offer sharps disposal services.

Can you travel with Wegovy on a plane?

Yes. Pack pens in your carry-on with an ice pack or insulated bag. Bring your prescription or a doctor's note. TSA allows medications and ice packs for medical use. Do not check Wegovy in luggage due to temperature extremes in cargo holds.

What happens if Wegovy gets too hot?

If exposed to temperatures above 86°F for more than 24 hours, semaglutide may lose potency. The medication will look normal but may not work as well. If you suspect heat damage, contact your pharmacy. There's no home test for potency.

Sources

1. Wilding JPH et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity. New England Journal of Medicine. 2021.
2. Rubino D et al. Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial. JAMA. 2021.
3. Davies M et al. Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes. New England Journal of Medicine. 2021.
4. Kosiborod MN et al. Semaglutide in Patients with Heart Failure with Preserved Ejection Fraction and Obesity. Diabetes Care. 2023.
5. Frid AH et al. New Injection Recommendations for Patients with Diabetes. Diabetes Therapy. 2016.
6. Frid A et al. Worldwide Injection Technique Questionnaire Study: Injecting Complications and the Role of the Professional. Mayo Clinic Proceedings. 2010.
7. Hirsch LJ et al. Comparative Glycemic Control, Safety and Patient Ratings for a New 4 mm × 32G Insulin Pen Needle. Diabetes Technology & Therapeutics. 2018.
8. Lingvay I et al. Obesity management as a primary treatment goal for type 2 diabetes: time to reframe the conversation. Obesity. 2022.
9. Wegovy (semaglutide) Prescribing Information. Novo Nordisk. 2021.
10. American Society of Anesthesiologists. Practice Guidelines for Preoperative Fasting. Anesthesiology. 2023.
11. Garvey WT et al. Two-year effects of semaglutide in adults with overweight or obesity: the STEP 5 trial. Nature Medicine. 2022.
12. Pi-Sunyer X et al. A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management. New England Journal of Medicine. 2015.
13. Blonde L et al. Interpretation and Impact of Real-World Clinical Data for the Practicing Clinician. Advances in Therapy. 2018.
14. Nauck MA et al. GLP-1 receptor agonists in the treatment of type 2 diabetes - state-of-the-art. Molecular Metabolism. 2021.

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Platform Disclaimer. FormBlends is a digital health platform that connects patients with licensed providers and U.S.-based pharmacies. We do not manufacture, prescribe, or dispense medication directly. All clinical decisions are made by independent licensed providers.

Compounded Medication Notice. Compounded semaglutide and tirzepatide are not FDA-approved. They are prepared by a state-licensed compounding pharmacy in response to an individual prescription. Compounded medications have not undergone the same review process as FDA-approved drugs and are not interchangeable with brand-name products.

Results Disclaimer. Individual results vary. Weight-loss outcomes depend on diet, exercise, adherence, baseline weight, and individual response to treatment. Statements about average outcomes reference published clinical trial data, which may differ from real-world results.

Trademark Notice. Wegovy is a registered trademark of Novo Nordisk. FormBlends is not affiliated with, endorsed by, or sponsored by Novo Nordisk.