MOTS-c Dosage Calculator
MOTS-c is a 16-amino-acid peptide encoded in mitochondrial DNA. It is sold in 5 mg to 40 mg vials, and the dose ranges online disagree with each other by a factor of fifty, which makes it a good example of why this calculator does not pre-fill doses for research peptides.
This page converts any MOTS-c vial into units per dose and lays out, honestly, what the human data do and do not say.
Forum protocols onlyThe ranges you see online come from forums and animal-study extrapolation. No human dose-finding trial exists. · Reviewed by the FormBlends Editorial Standards Team · 2026-09-03
Forum protocols onlyNo FDA label and no human trial of MOTS-c itself. The only human dosing data are for an analog, CB4211, at 25 mg daily.
Enter your dose to see the units to draw, the volume in mL, and how long the vial lasts.
FDA compounding status (2026-07-23): Not lawfully compoundable yet. Withdrawn from Category 2 in April 2026; PCAC recommended 7-5-2 on 07/23/2026; no rule yet.. Full status table and sources
What the MOTS-c dose evidence actually is
No FDA label and no human trial of MOTS-c itself. The only human dosing data are for an analog, CB4211, at 25 mg daily.
The only human dosing study is of an analog, CB4211, given at 25 mg subcutaneously once daily for 28 days in a phase 1b trial. MOTS-c itself has no published human dose-finding study and no label.
Forum protocols range from a few hundred micrograms daily to 5 to 10 mg two or three times a week. They cannot all be right, and none of them is a trial result. Enter what you were given.
MOTS-c units at each water volume
The table uses a 10 mg vial. Each cell is the draw on a U-100 insulin syringe for that dose at that water volume. Cells above 100 units do not fit a 1 mL syringe; cells below 10 units sit in the part of a 1 mL barrel where measurement error rises, and a 0.5 mL or 0.3 mL syringe reads them better.
| Dose | 10 mg + 1 mL10 mg/mL | 10 mg + 2 mL5 mg/mL | 10 mg + 3 mL3.333 mg/mL | 10 mg + 5 mL2 mg/mL |
|---|---|---|---|---|
| 0.5 mg | 5 units | 10 units | 15 units | 25 units |
| 1 mg | 10 units | 20 units | 30 units | 50 units |
| 2 mg | 20 units | 40 units | 60 units | 100 units |
| 5 mg | 50 units | 100 units | 150 (does not fit) | 250 (does not fit) |
The doses in this table are round numbers chosen to show the arithmetic. They are not recommendations; no label or human dose-finding trial exists for MOTS-c.
Mixing MOTS-c
A 10 mg vial with 2 mL gives 5 mg per mL, so 5 mg is a full 100-unit syringe and 2.5 mg is 50 units. If your dose is in the milligram range, mix with less water: 10 mg in 1 mL puts 5 mg at 50 units. If your dose is in the microgram range, mix with more.
Storing MOTS-c after mixing
Refrigerate after mixing. A 10 mg vial at 5 mg per dose is two doses. At 500 mcg daily it is 20 doses, inside 28 days.
MOTS-c calculator questions
How much bac water for 10 mg MOTS-c?
It depends on whether your dose is in milligrams or micrograms. One millilitre suits milligram doses (5 mg is 50 units). Two or more millilitres suit microgram doses.
How many units is 5 mg of MOTS-c?
Fifty units at 10 mg per mL (10 mg in 1 mL), 100 units at 5 mg per mL (10 mg in 2 mL), 25 units at 20 mg per mL (20 mg in 1 mL).
Is there a human study of MOTS-c dosing?
Not of MOTS-c itself. A related analog, CB4211, was tested at 25 mg daily in a phase 1b trial.
Why do MOTS-c dose ranges online disagree so much?
Because there is no anchor. Without a label or a human trial, every protocol is a guess, and different communities have settled on different guesses.
Sources
MOTS-c guide
Evidence, mechanism, side effects and regulatory status.
MOTS-c through FormBlends
Provider review, licensed pharmacy, labelled concentration.
The full peptide calculator
All peptides, pre-mixed vials, blends, mistakes and concentration changes.
Free downloads built from this calculator's math
Peptide Dosing and Reconstitution Chart 2026
20 pages, 12 peptides, every vial size, units at five water volumes, printable vial labels. PDF.
Bacteriostatic Water Cheat Sheet
How much to add, what one unit holds, the 28-day rule stated correctly, four mistakes to avoid. PDF.
28-Day GLP-1 Injection Tracker
Dose, units drawn, site, weight, side effects and the vial counting down. PDF and spreadsheet.
Other peptide calculators
Arithmetic only. This page converts the dose you enter into units and millilitres. It does not recommend a dose. MOTS-c is not an FDA-approved drug and no human dose-finding trial exists; any dose you enter should come from a prescriber. FormBlends connects patients with licensed providers and pharmacies and does not prescribe or dispense.
