AIO peptides and Power25: what the science says

What did @pe4power actually say?

The creator promoted a compound called "Lipo Fat Blaster" containing L-carnitine, methionine, inositol, choline (the so-called "McBlend"), vitamin B6, vitamin B12, and NADH. Their core pitch: these ingredients work together to transport fatty acids into cells for energy, boost metabolism, improve mood, and increase ATP production. They called all of these "research compounds" and framed the whole thing as informational only.

To be clear about what was actually said: this is a cosmetic disclaimer wrapped around what is functionally a product recommendation. Saying "consult your doctor" while explaining why each ingredient helps your metabolism and body composition is still marketing. That tension runs through the whole video.

Does the science back this up?

Partially, but with serious asterisks. L-carnitine has the strongest evidence base here. The MIC blend (methionine, inositol, choline) has been used in lipotropic injections for decades with limited rigorous trial data. Vitamin B12 and B6 claims are overstated. NADH is the most speculative.

L-carnitine's role in fatty acid transport is well-documented at the mechanistic level. Fielding et al. (2011, Journal of Physiology) showed oral L-carnitine supplementation increased muscle carnitine content and influenced fat oxidation during low-intensity exercise, though this required co-ingestion with carbohydrate and took 24 weeks. That is a long way from "accelerate recovery" in a short-form video. The MIC blend's lipotropic effects are largely supported by older, smaller studies and animal models. Vitamin B12 boosting metabolism in people who are not deficient? That claim lacks strong RCT support. NADH as an oral supplement driving meaningful ATP increases is still early-stage research, mostly in chronic fatigue contexts.

What did they get wrong or right?

They got L-carnitine's fatty acid transport mechanism right. That is textbook biochemistry. Credit where it is due. But several other claims are either exaggerated or missing important context.

Vitamin B12 "increasing metabolic rate" is a common misconception. B12 is involved in metabolic pathways, but supplementing it in a replete individual does not meaningfully raise basal metabolic rate. The evidence for this specific claim is thin. Kennedy (2016, Nutrients) reviewed B vitamins and energy metabolism and made clear that deficiency correction drives functional improvements, not supraphysiologic dosing in healthy people. The mood claim for vitamin B6 is similarly weak outside of deficiency or PMS-specific contexts. The creator also conflates NADH with NAD+ benefits, noting they are different while implying similar outcomes. They are metabolically related but oral NADH pharmacokinetics are not equivalent to NAD+ precursor supplementation. Braidy et al. (2019, Antioxidants and Redox Signaling) noted that oral NAD precursor bioavailability is complex and compound-dependent. Calling NADH an established energy driver based on current evidence is a stretch.

What should you actually know?

Lipotropic injection blends like this one are not FDA-approved treatments for fat loss or metabolic optimization. They are compounded formulations, which means quality, dosing, and sterility depend entirely on the compounding pharmacy. That matters a lot if you are considering injections.

The "research compounds" framing is doing a lot of work here. Some of these ingredients, like L-carnitine and B vitamins, are well-studied as individual nutrients. But the specific combination in this formulation, at whatever doses are being used, has not been validated in controlled clinical trials as a weight loss or body composition protocol. Synergy claims, specifically that the MIC blend works "synergistically," require evidence of interaction effects, not just evidence that each ingredient does something in isolation. That evidence does not exist here in any rigorous form. If you are interested in any of these compounds, a conversation with a physician who can evaluate your actual metabolic panel, including B12 status, carnitine levels, and liver function, is genuinely more useful than a TikTok video.