Direct answer: The U.S. Ozempic pen instructions do not provide a click-count conversion for microdoses such as 0.125 mg. They list dose settings for each pen presentation, and the dose counter identifies the selected labeled amount.
Settings listed for the U.S. pens
| Total pen contents | Labeled dose settings |
|---|---|
| 2 mg/3 mL | 0.25 mg or 0.5 mg |
| 4 mg/3 mL | 1 mg |
| 8 mg/3 mL | 2 mg |
The prescribing information describes a labeled titration schedule beginning at 0.25 mg once weekly for four weeks, followed by 0.5 mg once weekly. This schedule is separate from a click chart; it does not establish a smaller dial setting.
Why an online microdose chart cannot be inferred from clicks
The Instructions for Use direct the user to the dose counter and pointer and say not to set a dose by counting clicks. The listed presentations also have different concentrations and dose settings. A click count or arithmetic conversion is not a manufacturer-specified microdose setting.
Source
Novo Nordisk, U.S. Prescribing Information and Instructions for Use.
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