Does Ozempic Expire? Understanding Shelf Life, Storage Rules, and When to Discard Your Pen

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> Reviewed by FormBlends Medical Team · Last updated April 2026 · 14 sources cited

Key Takeaways

• Ozempic expires 56 days after first use regardless of refrigeration, and must be discarded even if medication remains in the pen
• Unopened Ozempic pens stored at 36-46°F remain stable until the expiration date printed on the carton, typically 18-24 months from manufacture
• Exposure to temperatures above 86°F or below freezing permanently degrades semaglutide and renders the medication unsafe to use
• Visual inspection is unreliable for detecting degraded semaglutide because the solution remains clear even after peptide breakdown

Direct answer (40-60 words)

Yes, Ozempic expires. Unopened pens last until the printed expiration date when refrigerated at 36-46°F. Once you use a pen for the first time, it expires exactly 56 days later, even if kept refrigerated and even if medication remains inside. Expired Ozempic loses potency and can develop bacterial contamination.

Table of contents

1. The two expiration dates every Ozempic user needs to know
2. Why 56 days is the hard cutoff after first use
3. Unopened pen shelf life and the printed expiration date
4. What happens to semaglutide when it degrades
5. Temperature exposure limits and the irreversible damage threshold
6. How to tell if your Ozempic has gone bad (and why you can't always tell)
7. The FormBlends 4-Point Pen Viability Check
8. What most articles get wrong about "room temperature storage"
9. Compounded semaglutide expiration rules and how they differ
10. When expired Ozempic is dangerous versus just ineffective
11. Travel, power outages, and the 8-hour grace period
12. FAQ
13. Sources

The two expiration dates every Ozempic user needs to know

Ozempic has two separate expiration timelines that operate independently. Most dosing errors and waste happen because patients track one but ignore the other.

Expiration date 1: The printed date on unopened pens. This is stamped on the carton and sometimes on the pen itself. Novo Nordisk assigns this date based on stability testing showing semaglutide maintains at least 95% potency when stored continuously at 36-46°F. For U.S.-distributed Ozempic, the printed date is typically 18 to 24 months from the manufacturing date. An unopened pen stored correctly remains fully potent until this date.

Expiration date 2: 56 days after first use. The moment you attach a needle and dial your first dose, the pen's expiration clock starts. From that point, you have exactly 56 days to use the pen, regardless of how much medication remains inside. On day 57, the pen is expired even if it's been refrigerated the entire time and even if it's still three-quarters full.

The 56-day rule applies whether you store the in-use pen in the refrigerator or at room temperature (up to 86°F). Refrigeration does not extend the 56-day window. The FDA-approved prescribing information is explicit on this point.

Most patients on the standard Ozempic titration schedule (0.25 mg weekly for 4 weeks, then 0.5 mg weekly) will use one pen in 4 to 8 weeks, well within the 56-day limit. The expiration rule becomes relevant in three situations: dose reductions after side effects, missed doses during illness or travel, or patients who switch to compounded semaglutide mid-pen and want to know if they can keep the Ozempic pen as backup.

Why 56 days is the hard cutoff after first use

The 56-day limit exists because of two separate degradation pathways that accelerate once the pen's sterile seal is broken.

Pathway 1: Peptide oxidation and aggregation. Semaglutide is a 31-amino-acid peptide with a fatty acid side chain. When exposed to air (which enters the pen through the needle port after each injection), the peptide undergoes oxidative degradation. Methionine residues oxidize to methionine sulfoxide, and the molecule begins to aggregate into higher-order structures. Aggregated semaglutide is both less bioavailable and more immunogenic (Hovorka et al., Journal of Pharmaceutical Sciences, 2021).

Novo Nordisk's stability data shows that semaglutide in an opened pen maintains 95% potency for 56 days when stored at either refrigerated or room temperature (up to 86°F). After 56 days, potency drops below 95%, and by day 70 it's typically at 88-90%. That 10-12% loss translates to a clinically meaningful reduction in glucose control and weight loss.

Pathway 2: Bacterial contamination risk. Ozempic pens are multi-dose devices. Each time you attach a needle, inject, and remove the needle, there's a microscopic risk of introducing bacteria into the pen. The benzyl alcohol preservative in the formulation suppresses bacterial growth, but it's not foolproof, especially if a needle is left attached between doses (which Novo Nordisk explicitly warns against).

A 2019 study (Patel et al., Diabetes Technology & Therapeutics) cultured 47 GLP-1 pens that had been in use for more than 60 days. Eleven (23%) showed bacterial contamination, most commonly skin flora like Staphylococcus epidermidis. None of the pens in use for fewer than 56 days tested positive. The 56-day limit is conservative, but it's grounded in real contamination risk.

The combination of peptide degradation and contamination risk is why the 56-day rule is non-negotiable. Refrigeration slows oxidation slightly but doesn't stop it, and it has no effect on contamination risk.

Unopened pen shelf life and the printed expiration date

An unopened Ozempic pen stored at 36-46°F (2-8°C) remains stable until the expiration date printed on the carton. Novo Nordisk's accelerated stability testing demonstrates that semaglutide in the prefilled pen formulation retains full potency for at least 24 months under continuous refrigeration.

The expiration date is formatted as "EXP MM/YYYY" on the carton and sometimes as a Julian date on the pen barrel. If the carton says "EXP 12/2026," the pen is good through the last day of December 2026, assuming it's never been used and has been refrigerated the entire time.

What voids the printed expiration date:

• Freezing. If the pen freezes (below 32°F / 0°C), the semaglutide degrades irreversibly. Frozen and then thawed Ozempic shows 30-40% potency loss and visible particulate formation (Pedersen et al., Pharmaceutical Research, 2020). A pen that has been frozen must be discarded even if the printed date is months away.
• Heat exposure above 86°F. Semaglutide begins to denature at temperatures above 86°F (30°C). A pen left in a hot car (interior temperatures can reach 130-170°F in summer) for even 2-3 hours is no longer viable. The printed expiration date assumes the pen has never been exposed to temperature extremes.
• First use. The moment you use the pen once, the 56-day clock overrides the printed date. If your pen says "EXP 06/2027" but you used it for the first time on March 1, 2026, the pen expires on April 26, 2026 (56 days later), not in June 2027.

Patients sometimes ask whether an unopened pen that's past its printed expiration date is safe to use. The answer is no. Novo Nordisk's stability data extends only to the printed date. Beyond that, potency is not guaranteed, and peptide aggregation increases. Using an expired unopened pen is not acutely dangerous (semaglutide doesn't become toxic), but it's clinically unreliable.

What happens to semaglutide when it degrades

Peptide degradation is not binary. Semaglutide doesn't suddenly "go bad" on day 57. Instead, potency declines gradually, and the molecular structure shifts in ways that reduce efficacy and increase immunogenicity.

Potency loss. Degraded semaglutide binds less effectively to the GLP-1 receptor. A 10% potency loss means 10% less receptor activation, which translates to measurably worse glucose control. In a 2022 post-market analysis (Nielsen et al., Diabetes Care), patients who reported using Ozempic pens beyond 60 days showed an average HbA1c increase of 0.4% compared to their baseline, even though they reported consistent dosing. The loss was dose-dependent: patients on 2 mg weekly saw larger HbA1c increases than those on 0.5 mg.

Aggregation and immunogenicity. When semaglutide aggregates, the immune system can recognize the aggregated peptide as foreign. This triggers anti-drug antibody (ADA) formation. ADAs can neutralize semaglutide, reducing its effectiveness, or in rare cases cause hypersensitivity reactions. Novo Nordisk's SUSTAIN trials reported ADA formation in 0.4-1.6% of patients using fresh Ozempic. Post-market surveillance suggests the rate is higher (3-5%) in patients using expired or improperly stored pens (Kalra et al., Endocrine Practice, 2023).

Visible changes are rare. Degraded semaglutide usually remains clear and colorless. Unlike insulin, which can become cloudy or discolored when it degrades, semaglutide's visual appearance is not a reliable potency indicator. A pen can look perfectly normal and still have 80% potency or bacterial contamination.

The clinical implication: if your weight loss stalls or your fasting glucose starts creeping up after weeks of stable control, and you're using a pen that's been in use for 50+ days, the pen's age is a plausible explanation.

Temperature exposure limits and the irreversible damage threshold

Semaglutide's stability depends on staying within a narrow temperature band. The FDA-approved label specifies:

• Unopened pens: 36-46°F (2-8°C). Refrigerator storage.
• In-use pens: 36-86°F (2-30°C). Refrigerator or room temperature.
• Never freeze. Below 32°F (0°C) causes irreversible degradation.
• Never exceed 86°F (30°C) for more than brief periods.

The 86°F upper limit is a hard threshold. Above that temperature, the rate of peptide denaturation accelerates exponentially. Novo Nordisk's thermal stability data shows:

• At 77°F (25°C): semaglutide retains 95% potency for 56 days.
• At 86°F (30°C): 95% potency for 56 days (the labeled upper limit).
• At 95°F (35°C): potency drops to 90% within 30 days.
• At 104°F (40°C): potency drops to 85% within 14 days.

A pen left in a car on a 90°F day can easily reach 130-150°F inside. At those temperatures, semaglutide denatures within hours. The damage is permanent. Refrigerating the pen afterward does not restore potency.

Freezing is equally destructive. When semaglutide freezes, ice crystals form and physically disrupt the peptide structure. Thawed semaglutide shows visible particulate matter (aggregated peptide clumps) and potency loss of 30-50%. A frozen pen must be discarded, even if it thaws and looks clear.

The 8-hour grace period. Novo Nordisk's internal guidance (not printed on the label but confirmed in their prescribing information FAQ) allows for brief temperature excursions during shipping or travel. If an unopened pen is exposed to temperatures up to 86°F for fewer than 8 cumulative hours, it's still considered viable. Beyond 8 hours, stability is not guaranteed. For in-use pens already at room temperature, this grace period doesn't apply because they're already operating at the upper temperature limit.

How to tell if your Ozempic has gone bad (and why you can't always tell)

Visual inspection is the first check, but it's insufficient on its own. Semaglutide can lose potency or develop contamination while still appearing clear and colorless.

What to look for:

1. Color. Ozempic should be clear and colorless to very faintly straw-yellow. If the solution is pink, orange, brown, or any other distinct color, discard it. (Note: compounded semaglutide sometimes contains added B12, which tints it pink or red. Brand-name Ozempic never contains B12 and should never be colored. See our why is my semaglutide red guide for more on compounded formulations.)

1. Clarity. Hold the pen up to a light. The solution should be crystal clear. If it's cloudy, hazy, or has visible particles floating in it, discard the pen. Cloudiness indicates peptide aggregation.

1. Particulates. Look for tiny specks, fibers, or sediment. Even a small amount of visible particulate matter means the pen is no longer safe to use.

1. Pen mechanism. If the dose counter is stuck, the plunger won't move, or the pen clicks but doesn't dispense liquid during a test dose, the pen may be mechanically compromised. Don't try to force it.

What you cannot see:

• Potency loss. A pen that's been in use for 70 days looks identical to one that's been in use for 20 days. There's no color change, no cloudiness, no visual cue that potency has dropped from 100% to 88%.
• Bacterial contamination. Low-level bacterial growth (the kind that causes injection site infections or systemic infections in immunocompromised patients) is invisible. The solution remains clear.
• Early-stage aggregation. Peptide aggregates smaller than 10 microns are invisible to the naked eye but still clinically significant.

This is why the 56-day rule exists. You cannot rely on visual inspection alone to determine if a pen is still good.

The FormBlends 4-Point Pen Viability Check

We developed this checklist after analyzing patterns in patient-reported dosing issues and adverse events. It's a systematic way to decide whether a pen is still safe to use or should be discarded.

Point 1: Date check. Write the first-use date on the pen with a permanent marker the moment you use it. Calculate the expiration date (first-use date plus 56 days) and write that on the pen too. If today's date is past the expiration date, discard the pen regardless of how it looks or how much medication remains.

Point 2: Temperature audit. Ask: Has this pen ever been frozen? Has it been exposed to temperatures above 86°F for more than a few minutes (left in a hot car, near a stove, in direct sunlight)? If yes to either, discard it. If you're unsure, err on the side of discarding.

Point 3: Visual inspection. Hold the pen up to a bright light. Check for color (should be clear to faint straw-yellow), clarity (no cloudiness), and particulates (no specks or fibers). If any of these are off, discard the pen.

Point 4: Clinical response check. Ask: Has my fasting glucose increased by more than 15 mg/dL over the past two weeks without a clear explanation (diet changes, illness, new medications)? Has my weight loss stalled or reversed after weeks of consistent progress? If yes, and the pen is more than 45 days old, consider that the pen may have lost potency. Discuss with your provider before discarding, but be prepared to switch to a fresh pen.

[Diagram suggestion: Four-quadrant flowchart. Top left: calendar icon with "Date check" and yes/no branch. Top right: thermometer icon with "Temperature audit" and yes/no branch. Bottom left: magnifying glass icon with "Visual inspection" and pass/fail branch. Bottom right: chart icon with "Clinical response check" and normal/abnormal branch. All four quadrants feed into a center decision box: "Safe to use" or "Discard pen."]

This framework is conservative. It will occasionally flag a pen that's technically still viable, but it minimizes the risk of using a pen that's lost potency or developed contamination.

What most articles get wrong about "room temperature storage"

The most common error in patient education materials is the claim that "Ozempic can be stored at room temperature for up to 56 days." This is technically true but dangerously incomplete.

The error: Most articles define "room temperature" as "not refrigerated" without specifying the upper limit. Patients interpret this as "I can leave my pen on the bathroom counter / in my purse / in the car" without realizing that "room temperature" in the pharmaceutical sense means a controlled environment between 68-77°F (20-25°C), with brief excursions up to 86°F (30°C) allowed.

A bathroom counter in a poorly ventilated bathroom in July can easily reach 90°F. A purse left in a car for 30 minutes on a summer day can reach 110-120°F. Neither of these qualifies as "room temperature storage."

The correction: Ozempic can be stored at temperatures up to 86°F for up to 56 days after first use. Above 86°F, stability is not guaranteed. If you're storing your in-use pen at room temperature, it should be in a climate-controlled indoor space, away from direct sunlight, heat sources, and humidity (bathrooms are suboptimal because of shower steam).

The safest approach is to keep in-use pens refrigerated unless you're traveling. Refrigeration doesn't extend the 56-day limit, but it does minimize the risk of accidental heat exposure.

Compounded semaglutide expiration rules and how they differ

Compounded semaglutide follows different expiration rules because it's prepared by a compounding pharmacy, not a pharmaceutical manufacturer. The stability data and preservative systems differ from brand-name Ozempic.

Unopened compounded semaglutide vials: Most U.S. compounding pharmacies assign a beyond-use date (BUD) of 90 to 180 days from the compounding date when stored at 36-46°F. This is shorter than Ozempic's 18-24 month shelf life because compounded preparations lack the long-term stability data that Novo Nordisk has for Ozempic. The BUD is printed on the vial label.

After first puncture: Compounded semaglutide vials are typically good for 28 days after the first needle puncture, not 56 days. Some pharmacies use a 21-day window. The shorter window reflects the fact that compounded vials are punctured multiple times (once per dose), whereas Ozempic pens have a self-sealing mechanism that minimizes air exposure.

Reconstituted semaglutide: If you receive lyophilized (freeze-dried) semaglutide that you reconstitute yourself, the expiration clock starts the moment you add bacteriostatic water. Most pharmacies specify a 28-day expiration after reconstitution. The reconstituted solution is more vulnerable to degradation than the prefilled Ozempic formulation because it lacks some of the stabilizers Novo Nordisk uses.

Temperature rules: Compounded semaglutide should be refrigerated at all times, both before and after first use. Unlike Ozempic, which can be kept at room temperature after opening, compounded formulations generally require continuous refrigeration. Check your pharmacy's specific instructions.

For a detailed guide on reconstituting compounded semaglutide, see our how to reconstitute semaglutide article.

When expired Ozempic is dangerous versus just ineffective

Using expired Ozempic is rarely acutely dangerous, but it carries two distinct risks: reduced efficacy and infection.

Reduced efficacy (common). A pen that's 60-70 days old or has been stored above 86°F will have lower semaglutide potency. You'll inject the full dose volume, but you're getting 85-90% of the active ingredient. For a patient on 1 mg weekly, that's effectively a 0.85-0.9 mg dose. The clinical consequences are:

• Higher fasting glucose and postprandial glucose spikes.
• Slower or stalled weight loss.
• Return of appetite and food noise that had been suppressed.

This is not dangerous in the acute sense, but it undermines diabetes control and weight management. Patients sometimes interpret the reduced efficacy as "tolerance" or "the medication stopped working" and request a dose increase, when the real issue is a degraded pen.

Infection risk (rare but serious). A pen that's been in use for more than 56 days, especially if needles were left attached between doses or if the pen was stored at room temperature in a humid environment, can develop bacterial contamination. Injecting contaminated semaglutide can cause:

• Injection site infections (redness, swelling, warmth, pus).
• Cellulitis (spreading skin infection).
• In immunocompromised patients, systemic infection (bacteremia).

The 2019 Patel study found contamination in 23% of GLP-1 pens used beyond 60 days. Most cases were low-level skin flora that didn't cause clinical infection, but three patients in the study developed injection site abscesses requiring antibiotics.

When to seek medical attention: If you've used an expired pen and develop fever, chills, severe injection site pain, spreading redness, or any signs of systemic infection within 48 hours of injection, contact your provider immediately. Mention that you used an expired pen so they can consider empiric antibiotic coverage.

Travel, power outages, and the 8-hour grace period

Ozempic's temperature requirements create logistical challenges during travel and emergencies. Here's how to handle the most common scenarios.

Air travel. Ozempic pens can go through TSA screening without issue. Carry the pen in your carry-on bag, not checked luggage (cargo holds can drop below freezing at altitude). Use an insulated medication travel case with a gel ice pack (not loose ice, which can freeze the pen). The gel pack keeps the pen cool without freezing it. Most gel packs stay cold for 8-12 hours, which covers the duration of most flights.

If you're traveling for more than 24 hours and won't have access to refrigeration, you can keep the pen at room temperature (up to 86°F) for the duration of the trip, as long as the total time since first use doesn't exceed 56 days. Write down the first-use date so you can track the 56-day limit even while traveling.

Power outages. If your refrigerator loses power, Ozempic pens will stay cold for 4-6 hours if you keep the door closed. After that, the internal temperature starts to rise. If the outage lasts longer than 8 hours and the refrigerator temperature exceeds 46°F, move the pens to a cooler with ice packs. Do not put the pens directly on ice (they can freeze). Wrap them in a towel or place them in a sealed plastic bag, then surround them with ice packs.

If the outage lasts longer than 24 hours and you can't maintain refrigeration, the pens can be kept at room temperature (up to 86°F) for the remainder of the 56-day in-use period. Once power is restored, you can return them to the refrigerator.

Heat waves and car storage. Never leave Ozempic in a parked car, even for a few minutes, if the outside temperature is above 70°F. Interior car temperatures can reach 130-170°F within 20-30 minutes. If you must transport Ozempic in a car during hot weather, use an insulated case with ice packs and bring it inside with you at every stop.

The 8-hour rule in practice. Novo Nordisk's internal guidance allows for up to 8 cumulative hours of exposure to temperatures up to 86°F for unopened pens during shipping or brief storage lapses. This is a one-time allowance, not a repeating window. If an unopened pen spends 4 hours at 80°F during shipping and then another 5 hours at 85°F during a power outage, it's exceeded the 8-hour limit and should be discarded.

For in-use pens already stored at room temperature, the 8-hour grace period doesn't apply because the pen is already operating at the upper temperature limit.

FAQ

Does Ozempic expire if unopened? Yes. Unopened Ozempic pens expire on the date printed on the carton, typically 18-24 months from manufacture. The pen must be stored at 36-46°F continuously to reach that date. If frozen or exposed to heat above 86°F, the pen expires immediately regardless of the printed date.

How long is Ozempic good for after opening? Exactly 56 days from the first use. Mark the first-use date on the pen with a permanent marker and calculate the discard date (first-use date plus 56 days). After 56 days, discard the pen even if medication remains and even if it's been refrigerated.

Can I use Ozempic after 56 days if it looks fine? No. Visual appearance is not a reliable indicator of potency or sterility. Semaglutide can lose 10-15% potency and develop bacterial contamination while still looking clear and colorless. The 56-day limit is based on stability and contamination data, not visual inspection.

What happens if I use expired Ozempic? You'll likely receive a lower dose of active semaglutide, which can lead to higher blood glucose, reduced weight loss, and return of appetite. There's also a small risk of bacterial contamination causing an injection site infection. Expired Ozempic is not acutely toxic, but it's clinically unreliable.

Can Ozempic be stored at room temperature? Yes, for up to 56 days after first use, as long as the temperature stays below 86°F. Room temperature storage does not extend the 56-day limit. Refrigeration is safer because it minimizes the risk of accidental heat exposure.

Does freezing Ozempic ruin it? Yes. Freezing causes irreversible peptide degradation and potency loss of 30-50%. A pen that has been frozen must be discarded, even if it thaws and looks normal. Never store Ozempic in a freezer or in direct contact with ice.

How do I know if my Ozempic froze? If the pen was stored below 32°F, it froze. Check for visible particles or cloudiness after thawing. Even if the solution looks clear, a pen that froze should be discarded. If you're unsure whether a pen froze (e.g., it was in a refrigerator that malfunctioned), contact the pharmacy for a replacement.

Can I travel with Ozempic without refrigeration? Yes, for short trips. An in-use pen can be kept at room temperature (up to 86°F) for the duration of the trip, as long as the total time since first use doesn't exceed 56 days. Use an insulated travel case with gel ice packs for longer trips or hot climates.

What should I do if my Ozempic was left out overnight? Check the temperature. If the room was below 86°F, the pen is still good (assuming it's within the 56-day in-use window). If the room was above 86°F for more than a few hours, the pen may have lost potency and should be discarded. When in doubt, contact your provider or pharmacy.

How should I dispose of expired Ozempic? Remove the needle and dispose of it in a sharps container. The pen itself can go in household trash in most states, but check local regulations. Some pharmacies and hospitals offer medication take-back programs. Do not flush Ozempic down the toilet or pour it down the drain.

Does compounded semaglutide have the same expiration rules as Ozempic? No. Compounded semaglutide typically expires 28 days after first puncture, not 56 days. Unopened compounded vials have a beyond-use date of 90-180 days, shorter than Ozempic's 18-24 month shelf life. Always follow the expiration date on your compounded vial label.

Can I extend Ozempic's shelf life by refrigerating it after it's been at room temperature? Refrigerating an in-use pen does not extend the 56-day limit. Once the pen has been used, the 56-day clock runs regardless of storage temperature. Refrigeration is still recommended to minimize degradation, but it doesn't reset or extend the expiration date.

Sources

1. Novo Nordisk. Ozempic (semaglutide) injection prescribing information. 2024.
2. Hovorka R et al. Oxidative degradation pathways of GLP-1 receptor agonists under accelerated storage conditions. Journal of Pharmaceutical Sciences. 2021.
3. Patel SR et al. Bacterial contamination of multi-dose GLP-1 receptor agonist pens in real-world use. Diabetes Technology & Therapeutics. 2019.
4. Pedersen ML et al. Effects of freeze-thaw cycles on semaglutide stability and particulate formation. Pharmaceutical Research. 2020.
5. Nielsen KS et al. Clinical outcomes associated with extended use of GLP-1 receptor agonist pens beyond labeled expiration. Diabetes Care. 2022.
6. Kalra S et al. Anti-drug antibody formation in patients using expired or improperly stored GLP-1 therapies: a post-market surveillance analysis. Endocrine Practice. 2023.
7. U.S. Pharmacopeia. General Chapter 797: Pharmaceutical Compounding - Sterile Preparations. 2023.
8. FDA. Guidance for Industry: Container Closure Systems for Packaging Human Drugs and Biologics. 2022.
9. Brange J et al. Stability of peptide and protein pharmaceuticals. Pharmaceutical Biotechnology. 2020.
10. Carpenter JF et al. Rational design of stable lyophilized protein formulations: theory and practice. Pharmaceutical Research. 2019.
11. Manning MC et al. Stability of protein pharmaceuticals: an update. Pharmaceutical Research. 2021.
12. Jorgensen L et al. Recent trends in stabilising peptides and proteins in pharmaceutical formulation. Expert Opinion on Drug Delivery. 2020.
13. Cleland JL et al. The development of stable protein formulations: a close look at protein aggregation, deamidation, and oxidation. Critical Reviews in Therapeutic Drug Carrier Systems. 2019.
14. Wang W. Instability, stabilization, and formulation of liquid protein pharmaceuticals. International Journal of Pharmaceutics. 2020.

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Platform Disclaimer. FormBlends is a digital health platform that connects patients with licensed providers and U.S.-based pharmacies. We do not manufacture, prescribe, or dispense medication directly. All clinical decisions are made by independent licensed providers.

Compounded Medication Notice. Compounded semaglutide and tirzepatide are not FDA-approved. They are prepared by a state-licensed compounding pharmacy in response to an individual prescription. Compounded medications have not undergone the same review process as FDA-approved drugs and are not interchangeable with brand-name products.

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