Key Takeaway
Detailed dosage guide for the BPC-157 and TB-500 recovery stack. Covers dose ranges, body weight adjustments, injury-specific dosing, reconstitution calculator math, and how to adjust based on healing progress.
BPC-157 is typically dosed at 250 to 500 mcg per injection once or twice daily, while TB-500 is dosed at 2 to 2.5 mg per injection once or twice weekly, with both administered subcutaneously. The exact dose depends on injury severity, body weight, treatment phase, and individual response.
BPC-157 Dosage Details
Standard Dose Range
- Low dose: 200-250 mcg per injection (suitable for mild injuries or maintenance)
- Standard dose: 250-500 mcg per injection (most common therapeutic range)
- High dose: 500-750 mcg per injection (severe injuries, under clinical guidance)
Dosing Frequency
- Acute healing phase: Twice daily (morning and evening, approximately 12 hours apart)
- Consolidation phase: Once daily
- Maintenance phase: Once daily or every other day
Total Daily Dose
Most protocols result in a total daily BPC-157 dose of 250 to 1000 mcg (0.25 to 1 mg). The twice-daily approach at 250 mcg per injection (500 mcg total daily) is the most commonly cited protocol across clinical practices.
TB-500 Dosage Details
Standard Dose Range
- Low dose: 1-1.5 mg per injection (lighter individuals or mild injuries)
- Standard dose: 2-2.5 mg per injection (most common)
- High dose: 5 mg per injection (severe injuries, loading phase, under clinical guidance)
Dosing Frequency
- Loading phase (weeks 1-4): Twice per week (for example, Monday and Thursday)
- Consolidation phase (weeks 5-8): Once per week
- Maintenance phase (weeks 9+): Once every 2 weeks
Total Weekly Dose
During the loading phase, total weekly TB-500 intake is typically 4 to 5 mg. This drops to 2 to 2.5 mg during consolidation and 2 mg every two weeks during maintenance.
View data table
| Category | Clinical Interest Score | Detail |
|---|---|---|
| BPC-157 | 88 | Tissue repair and gut healing |
| TB-500 | 82 | Injury recovery |
| Sermorelin | 78 | Growth hormone support |
| Ipamorelin | 75 | Anti-aging and recovery |
| GHK-Cu | 70 | Skin and tissue repair |
Combined Stack Dosing by Injury Severity
Mild Injuries (Minor Strains, Mild Tendonitis, Overuse)
| Peptide | Dose | Frequency | Duration |
|---|---|---|---|
| BPC-157 | 250 mcg | Once daily | 4-6 weeks |
| TB-500 | 2 mg | Once per week | 4-6 weeks |
Moderate Injuries (Partial Tears, Significant Tendinopathy, Post-Surgical)
| Peptide | Dose | Frequency | Duration |
|---|---|---|---|
| BPC-157 | 500 mcg | Twice daily (weeks 1-4), once daily (weeks 5-8) | 8-12 weeks |
| TB-500 | 2.5 mg | Twice per week (weeks 1-4), once per week (weeks 5-8) | 8-12 weeks |
Severe Injuries (Complete Tears, Major Surgery, Chronic Degenerative Conditions)
| Peptide | Dose | Frequency | Duration |
|---|---|---|---|
| BPC-157 | 500-750 mcg | Twice daily (weeks 1-6), once daily (weeks 7-12) | 12+ weeks |
| TB-500 | 2.5-5 mg | Twice per week (weeks 1-6), once per week (weeks 7-12) | 12+ weeks |
Body Weight Adjustments
While most BPC-157 and TB-500 protocols use fixed doses, body weight can influence response, particularly with TB-500:.
Check your GLP-1 eligibility
Use our free BMI Calculator to see if you may qualify for provider-reviewed GLP-1 therapy.
Try the BMI Calculator →- Under 130 lbs (60 kg): Consider the lower end of dose ranges (BPC-157: 200-250 mcg. TB-500: 1.5-2 mg)
- 130-200 lbs (60-90 kg): Standard doses are appropriate
- Over 200 lbs (90 kg): May benefit from higher end of ranges (BPC-157: 500 mcg. TB-500: 2.5 mg)
Dose adjustments should be guided by clinical response and provider recommendations rather than weight calculations alone.
Reconstitution and Dosing Math
BPC-157
BPC-157 commonly comes in 5 mg vials. When reconstituted with 2 mL of bacteriostatic water:
- Concentration = 2.5 mg/mL (2500 mcg/mL)
- 250 mcg dose = 0.1 mL (10 units on an insulin syringe)
- 500 mcg dose = 0.2 mL (20 units on an insulin syringe)
- One 5 mg vial provides 10 doses at 500 mcg or 20 doses at 250 mcg
Peptide reconstitution calculator
TB-500
TB-500 commonly comes in 5 mg or 10 mg vials. When reconstituting a 5 mg vial with 2 mL of bacteriostatic water:
- Concentration = 2.5 mg/mL
- 2 mg dose = 0.8 mL (80 units on an insulin syringe)
- 2.5 mg dose = 1.0 mL (100 units on an insulin syringe)
- One 5 mg vial provides 2 doses at 2.5 mg
When reconstituting a 10 mg vial with 2 mL of bacteriostatic water:
- Concentration = 5 mg/mL
- 2 mg dose = 0.4 mL (40 units)
- 2.5 mg dose = 0.5 mL (50 units)
- One 10 mg vial provides 4 doses at 2.5 mg
Oral BPC-157 Dosing
For gut-focused applications, BPC-157 can be taken orally. Oral dosing is typically higher than subcutaneous dosing to account for reduced bioavailability through the digestive tract.
- Oral BPC-157: 250-500 mcg, twice daily, on an empty stomach
- Oral capsules (stable arginine salt form): Follow manufacturer's dosing instructions, typically 250-500 mcg per capsule
Oral BPC-157 is particularly effective for gastric ulcers, intestinal inflammation, and gut barrier repair. For musculoskeletal injuries, subcutaneous injection near the injury site remains the preferred route. oral vs injectable BPC-157
Timing Your Doses
BPC-157 Timing
- No fasting required
- For twice-daily dosing, space injections approximately 12 hours apart (for example, 7 AM and 7 PM)
- Some practitioners recommend dosing after exercise to capitalize on the recovery window
TB-500 Timing
- No fasting required
- For twice-weekly dosing, space injections 3-4 days apart (for example, Monday and Thursday)
- Can be administered at any time of day
When to Increase or Decrease Your Dose
Consider Increasing If
- Minimal healing progress after 3-4 weeks at the current dose
- Injury is severe and initial assessment suggests higher dosing is appropriate
- No side effects at the current dose
- Provider recommends titration based on clinical assessment
Consider Decreasing If
- Significant healing has occurred and maintenance is the goal
- Any unexpected side effects (rare with these peptides)
- Transitioning from acute healing to consolidation phase
- Cost management over a long treatment course
Cost at Different Dose Levels
Monthly costs vary based on dosing frequency and source:
- Low-dose maintenance: Approximately $100-150/month Contact provider for current pricing Contact provider for current pricing
- Standard acute protocol: Approximately $200-350/month
- High-dose intensive protocol: Approximately $350-500+/month
Pre-mixed BPC-157/TB-500 blends from compounding pharmacies can offer cost savings compared to purchasing separate vials. peptide cost comparison
Frequently Asked Questions
- What is the most common BPC-157 dose?
-
The most widely used BPC-157 dose is 250-500 mcg per injection, administered once or twice daily via subcutaneous injection. A total daily dose of 500 mcg (either as a single injection or split into two 250 mcg injections) is the most commonly cited across clinical peptide practices.
- How much TB-500 should I take per week?
-
During the loading phase, 4-5 mg per week (split into two injections of 2-2.5 mg) is standard. During consolidation, this drops to 2-2.5 mg once per week. During maintenance, 2 mg every two weeks is common. Your provider can adjust these amounts based on your injury and response.
- Can I take a higher dose to heal faster?
-
There's a ceiling to dose-response benefits. Doubling the dose doesn't necessarily double the healing speed. Staying within established therapeutic ranges is more effective and safer than dramatically exceeding them. If healing is slower than expected, discuss improvement strategies with your provider rather than arbitrarily increasing doses.
- How many vials will I need for a full cycle?
-
For an 8-week standard protocol (BPC-157 at 500 mcg twice daily, TB-500 at 2.5 mg twice weekly for 4 weeks then weekly): you would need approximately 11-12 vials of BPC-157 (5 mg each) and 5-6 vials of TB-500 (5 mg each). Pre-mixed blends or larger vial sizes can reduce the total number of vials needed. recovery stack supply calculator
- Is twice-daily BPC-157 necessary, or is once daily enough?
-
Once-daily dosing is effective for many injuries, particularly mild to moderate conditions. Twice-daily dosing maintains more consistent tissue levels and is generally recommended for acute injuries, severe conditions, or during the initial 2-4 weeks of treatment. Your provider can help determine the appropriate frequency based on your specific situation.