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Peptide Therapy Guide

Everything you need to know about peptide therapy. Browse individual peptides, treatment categories, and popular stacking combinations.

The regulatory picture for US peptide compounding changed in September 2023 and is being rewritten again under RFK-era HHS. Full context lives in our 2026 State of Peptides & GLP-1 Regulation report.

Peptides by Use Case

Individual Peptides

Weight Loss

Semaglutide

The GLP-1 receptor agonist that transformed weight loss medicine with proven cardiovascular benefits

$129-349/month (compounded); $349-1,349/month (brand self-pay)

Weight Loss

Tirzepatide

Dual GLP-1/GIP agonist that outperforms semaglutide for weight loss in head-to-head trials

$150-300/month (compounded, limited availability); $299-1,086/month (brand)

HRT

HCG

LH-mimicking hormone that preserves testicular function and fertility during TRT

$60-200/month

Recovery

BPC-157

Gut-derived healing peptide that accelerates tissue repair and reduces inflammation

$100-250/month

Sexual Wellness

Oxytocin

Neuropeptide that influences bonding, sexual function, and stress response

$40-100/month

Growth Hormone

Sermorelin

Growth hormone releasing peptide that restores natural GH production safely

$150-350/month

HRT

Testosterone Enanthate

Long-acting testosterone ester for hormone replacement and hypogonadism treatment

$30-80/month

Weight Loss

Retatrutide

Triple agonist targeting GLP-1, GIP, and glucagon receptors for the deepest weight loss in clinical trials

$200-650/month (research suppliers, legally questionable)

Immune

Glutathione

The body's master antioxidant, available as IV, injection, liposomal, and oral supplement forms

$20-80/month (oral/liposomal); $100-200/month (SC injection); $200-900/month (IV sessions)

HRT

Anastrozole

Aromatase inhibitor that controls estrogen levels during testosterone therapy

$10-30/month

HRT

Enclomiphene

Selective estrogen receptor modulator that boosts testosterone while preserving fertility

$40-120/month

Growth Hormone

Tesamorelin

FDA-approved GHRH analog that reduces visceral fat and improves body composition

$150-450/month (compounded); $3,000-6,000/month (brand Egrifta without insurance)

HRT

Clomiphene Citrate

Selective estrogen receptor modulator that raises endogenous testosterone by stimulating the HPG axis

$15-40/month

Weight Loss

Orforglipron

First oral non-peptide GLP-1 agonist: a daily pill with no food restrictions or injections

$25-349/month

Anti-Aging

NMN

NAD+ precursor that restores cellular energy metabolism

$30-100/month

Weight Loss

AOD-9604

Fat-burning peptide fragment that stimulates lipolysis without growth hormone side effects

$40-200/month

HRT

Testosterone Cypionate

The most commonly prescribed form of testosterone replacement in the US

$30-100/month

HRT

Pregnenolone

Master precursor hormone that feeds downstream production of cortisol, DHEA, testosterone, and estrogen

$10-30/month

HRT

Estradiol

The primary estrogen used in female hormone replacement therapy

$20-80/month

HRT

Gonadorelin

Synthetic GnRH analog that stimulates natural LH and FSH production as an alternative to HCG

$50-150/month

Skin and Healing

Melanotan II

Melanocortin receptor agonist that produces tanning, libido enhancement, and appetite suppression

$30-80 per 10 mg vial

Growth Hormone

Tesamorelin

FDA-approved GHRH analog that reduces visceral fat and stimulates natural growth hormone production

$400-800/month

Growth Hormone

Ipamorelin

Selective growth hormone peptide that boosts GH without cortisol spikes

$150-300/month

HRT

Progesterone

The bioidentical progesterone used alongside estradiol in female HRT

$20-60/month

Recovery

KPV

Anti-inflammatory tripeptide derived from alpha-MSH that targets gut inflammation at the cellular level

$80-180/month

Growth Hormone

GHRP-2

The strongest growth hormone releasing peptide, used diagnostically in Japan for GH deficiency testing

$20-50 per 5 mg vial (research); $100-250/month compounded

Muscle Growth

IGF-1 LR3

Extended-action IGF-1 analog that activates muscle satellite cells for both hypertrophy and hyperplasia

$60-120 per 1 mg vial (research); $200-400/month estimated clinic cost

Growth Hormone

GHRP-6

Growth hormone secretagogue with strong appetite-stimulating effects through the ghrelin receptor

$50-120/month

Growth Hormone

MK-677

Oral growth hormone secretagogue that raises GH and IGF-1 levels daily

$50-150/month

HRT

DHEA

The most abundant steroid hormone precursor in the body, declining sharply with age

$10-40/month

Immune

LL-37

Human antimicrobial peptide that fights infections and modulates the immune response

$150-300/month

Muscle Growth

Follistatin 344

Myostatin-blocking protein that promotes muscle growth through dual anti-catabolic mechanisms

$50-120 per 1 mg vial ($150-360 per 30-day cycle)

Growth Hormone

GHRP-6

The original growth hormone releasing peptide with strong appetite stimulation and cardioprotective research

$15-40 per 5 mg vial (research); $80-200/month compounded

Growth Hormone

GHRP-2

Potent growth hormone secretagogue that stimulates GH release through the ghrelin receptor

$60-150/month

Growth Hormone

CJC-1295

Long-acting growth hormone releasing peptide for sustained GH elevation

$150-300/month

Recovery

VIP

Neuropeptide that regulates inflammation, circadian rhythm, and pulmonary function

$120-250/month

Growth Hormone

Hexarelin

GH secretagogue with unique cardiac protective effects through CD36 receptor binding

$40-80 per 2 mg vial (research); $150-300/month if clinic-sourced

Growth

Follistatin 344

Myostatin inhibitor that promotes muscle growth by removing natural growth limiters

$150-400/month

Metabolic

5-Amino-1MQ

NNMT inhibitor that shifts cellular metabolism toward fat burning and away from fat storage

$100-250/month

Recovery

TB-500

Wound healing peptide that promotes cell migration and tissue repair

$120-250/month

Cognitive

Dihexa

Potent nootropic peptide derivative that promotes synaptogenesis and cognitive enhancement

$60-150/month

Cognitive

DSIP

Sleep-normalizing nonapeptide that promotes deep delta-wave sleep without sedation

$30-60 per 5 mg vial (research); $100-250/month compounded

Weight Loss

Tesofensine

Triple monoamine reuptake inhibitor that produced ~10% weight loss in Phase 2 after being discovered as a Parkinson's drug side effect

$90-300/month

Growth Hormone

CJC-1295 with DAC

Long-acting GHRH analog with extended half-life for sustained growth hormone elevation

$80-200/month

Sleep & Stress

DSIP

Neuropeptide that promotes slow-wave sleep and modulates stress hormone response

$50-120/month

Sexual Health

PT-141

Melanocortin receptor peptide that treats sexual dysfunction in men and women

$200-400/month through compounding pharmacies. Vyleesi brand pricing significantly higher.

Recovery

Thymosin Beta-4

Full-length tissue repair peptide that promotes cell migration, wound healing, and cardiac protection

$150-350/month

Skin & Hair

SNAP-8

Topical peptide that reduces expression lines by modulating neuromuscular signaling at the skin level

$30-80/month

Anti-Aging

SS-31

Mitochondria-targeted peptide that restores cellular energy production

$200-500/month

Gut Health

Larazotide

Tight junction regulator that reduces intestinal permeability and targets leaky gut at the cellular level

$100-250/month (estimated, based on compounding availability)

Immune

Thymulin

Thymus-derived zinc-bound peptide that modulates T-cell development and immune regulation

$80-200/month

Skin & Hair

AHK-Cu Copper Peptide

Copper-binding tripeptide that stimulates hair follicle growth factors and supports skin rejuvenation

$40-120/month

Longevity

NAD+

Cellular energy coenzyme critical for DNA repair and healthy aging

$150-500/month depending on route. IV infusions typically $250-750 per session.

Anti-Aging

Humanin

Mitochondrial-derived peptide that protects against age-related cellular stress

$200-400/month

Skin and Healing

GHK-Cu

Copper-binding peptide that remodels skin, heals wounds, and stimulates collagen

$40-100/month for topical products. $100-200/month for injectable formulations.

Longevity

Epithalon

Pineal peptide that activates telomerase and targets biological aging

$150-300 per cycle (10-20 day protocol)

Cognitive

Selank

Synthetic tuftsin peptide with anxiolytic and immune-boosting properties

$80-180/month

Cognitive

Semax

Synthetic ACTH fragment that boosts BDNF and protects neurons

$80-200/month

Immune

Thymosin Alpha-1

Immune-regulating peptide approved in 30+ countries for infection and immune support

$200-400/month

Hormonal

Kisspeptin

Hormone-regulating peptide that drives reproductive function and GnRH release

$200-500/month (limited availability, primarily through research or specialized clinics)

Metabolic

MOTS-c

Mitochondrial peptide that mimics exercise and improves metabolic health

$150-350/month

Popular Stacks

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