Melanotan II How To Reconstitute: Complete Guide
Quick Answer: To reconstitute Melanotan II, add 1 to 2 mL of bacteriostatic water to a 10 mg lyophilized vial. Direct the water against the glass wall (never directly onto the powder), then gently swirl until dissolved. Do not shake. This creates a solution of 5-10 mg/mL that should be refrigerated and used within 28 days .
Supplies Needed
- Melanotan II lyophilized vial (typically 10 mg)
- Bacteriostatic water for injection (USP grade)
- Sterile mixing syringe (1-3 mL)
- Alcohol swabs
- Insulin syringes (29-31 gauge) for dosing
Reconstitution Steps
- Wash hands thoroughly with soap and water. Clean workspace with alcohol.
- Swab both vial stoppers (Melanotan II and bacteriostatic water) with alcohol pads. Air dry 10 seconds.
- Draw bacteriostatic water: Using a sterile syringe, draw 2 mL of BAC water (recommended for easier dosing).
- Add water to Melanotan II vial: Insert needle through stopper, angle toward the glass wall, and slowly release water so it trickles down the side. Never spray directly onto the powder .
- Let dissolve: Gently swirl the vial or let it sit for 5 to 10 minutes. Do not shake.
- Verify clarity: Solution should be clear and colorless. If cloudy or containing particles after 15 minutes, do not use.
- Refrigerate immediately at 36-46°F (2-8°C).
| BAC Water | Concentration | 100 mcg = Units | 250 mcg = Units | 500 mcg = Units |
|---|---|---|---|---|
| 1 mL | 10 mg/mL | 1 unit | 2.5 units | 5 units |
| 2 mL | 5 mg/mL | 2 units | 5 units | 10 units |
We recommend 2 mL for most users. The lower concentration makes it easier to measure accurate doses on a standard insulin syringe.
Common Mistakes
- Shaking the vial: Creates foam, damages the peptide. Gentle swirl only.
- Using sterile water instead of BAC water: No preservative means the vial must be used within 24 hours.
- Spraying water directly onto powder: Force can damage the peptide structure.
- Leaving at room temperature: Refrigerate immediately after reconstitution.
- Incorrect math: Double-check your reconstitution ratio before drawing doses.
After Reconstitution
Store the reconstituted vial in the refrigerator (back of a shelf, not the door). Use within 28 days. Label the vial with the reconstitution date. For detailed storage guidance, see our Melanotan II storage instructions guide. For injection technique, see our Melanotan II how to inject guide.
Frequently Asked Questions
How long does reconstituted Melanotan II last?
Up to 28 days when stored properly in the refrigerator and reconstituted with bacteriostatic water. Discard after 28 days regardless of remaining volume.
Can I freeze reconstituted Melanotan II?
No. Freezing causes ice crystals that damage the peptide structure. Only freeze unreconstituted (lyophilized) powder.
My solution is slightly cloudy. Is it still good?
Slight haziness immediately after mixing is normal. If cloudiness persists after 15 minutes of gentle swirling, or if you see particles, discard the vial.
Can I reconstitute with more water for easier measuring?
Yes. Adding more water creates a more dilute solution with larger per-dose volumes, making measurement easier. Just recalculate your units per dose accordingly.
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Disclaimer: This article is for informational purposes only and does not constitute medical advice. Melanotan II is not FDA-approved for any medical condition. Always consult with a licensed healthcare provider before beginning any peptide therapy. Individual results may vary.