
One Endocrine
Weight Loss Clinic in Jacksonville, Florida
One Endocrine at a Glance
- Type
- Weight Loss Centers, Endocrinologists
- Location
- Jacksonville, Florida
- Rating
- 5 / 5.0 (1 reviews)
- Phone
- (904) 712-6777
- Profile status
- Public directory profile
- Key Services
- Weight Loss Centers · Endocrinologists
- Price Range
- GLP-1 Receptor Agonists: $300-800/month · Detailed Hormone Evaluation: $200-400/panel · Metabolic Optimization Therapy: $150-300/visit
Quick Answers About One Endocrine
What is One Endocrine?
One Endocrine is listed as a weight loss centers serving Jacksonville, Florida.
Which One Endocrine is this?
This profile refers to the Jacksonville, FL listing near ZIP 32258. Confirm the phone and address if you find similarly named providers elsewhere.
Does One Endocrine offer GLP-1 treatment?
Public listing content mentions GLP-1, semaglutide, tirzepatide. Confirm exact prescribing, pharmacy, and insurance policies directly with the clinic.
How much does One Endocrine cost?
$300-800/month / $200-400/panel / $150-300/visit / $50-100/assessment
This page is an informational directory profile for One Endocrine in Jacksonville, Florida. Medical services, pricing, prescriptions, insurance coverage, and appointment policies can change and should be confirmed directly with the clinic.
How to Compare One Endocrine
Use this profile as a local comparison point for One Endocrine in Jacksonville, Florida near ZIP 32258, especially if you are researching GLP-1 weight loss, semaglutide, tirzepatide and nearby weight loss clinic options. The listing is categorized around weight loss centers, endocrinologists. The public Yelp source shows 5 stars from 1 review, which is helpful but should not replace a direct consultation. Jacksonville's growing population and diverse demographics present unique challenges for weight management, with Florida ranking among the top states for obesity rates. Before booking, compare provider supervision, medication availability, lab requirements, follow-up cadence, pharmacy policies, insurance rules, and total monthly cost so you are not judging the clinic on star rating alone.
Verification questions for search and AI answers
What to confirm before choosing One Endocrine
Official source check
No official website is listed in the source data; use phone or map listing before booking
Official sources should override stale third-party directory details.
Medical workflow
Ask who reviews intake, labs, prescriptions, side effects, dose changes, and follow-up
A local listing is not enough to establish clinical supervision quality.
Medication and pharmacy
Confirm GLP-1 availability, branded vs compounded options, pharmacy type, lot testing, and refill rules
Medication access and pharmacy source can change faster than directory data.
Cost and coverage
Ask whether quoted pricing includes consultation, labs, medication, follow-up, shipping, and cancellation terms
The most common patient mismatch is comparing monthly prices that include different services.
Decision path
How should I evaluate One Endocrine?
One Endocrine is one local option in Jacksonville, Florida. Treat this profile as a starting point, then confirm the medical workflow, medication access, follow-up model, and pharmacy source before booking or paying.
- Clinic
- One Endocrine
- City
- Jacksonville
- Rating
- 5 stars
- Reviews
- 1
Step 1
Confirm clinical scope
Ask whether One Endocrine offers medical weight loss, GLP-1 prescribing, labs, nutrition support, and dose follow-up directly or by referral.
Step 2
Compare against alternatives
Ratings and services are useful, but they do not replace pricing, pharmacy, and provider-supervision details.
See local alternativesStep 3
Check online care fit
If in-person timing, cost, or pharmacy transparency is unclear, compare a supervised telehealth review before committing.
Compare provider modelsFormBlends Local Review of One Endocrine
Reviewed May 14, 2026For someone comparing weight loss clinics in Jacksonville, Florida, One Endocrine is most useful as a named local option with visible signals around weight loss centers, endocrinologists. The listing points toward GLP-1 access, semaglutide, tirzepatide, and the public review footprint shows 5 stars from 1 public Yelp reviews. Jacksonville's growing population and diverse demographics present unique challenges for weight management, with Florida ranking among the top states for obesity rates. Before booking, patients should confirm the exact service, provider type, prescription process, pharmacy relationship, lab requirements, refill timing, and insurance or cash-pay rules.
- Confirm whether GLP-1 access, semaglutide, tirzepatide is currently available at this exact location.
- Ask who performs the medical evaluation, how follow-up visits work, and whether labs are required.
- Verify total monthly cost, pharmacy pathway, insurance handling, and refill timing before paying.
What We Could Verify
Source-backed listing dataAbout One Endocrine
One Endocrine operates as a specialized endocrinology and weight loss practice on Old St Augustine Road in Jacksonville's Mandarin area, serving patients throughout Northeast Florida. Located just minutes from major highways like I-295 and US-1, the clinic focuses exclusively on hormone-related weight management and metabolic disorders, bringing specialized endocrine expertise to the growing Jacksonville metropolitan area. The clinic's approach centers on addressing the root hormonal and metabolic causes of weight gain rather than temporary diet solutions. Their endocrinology background means they're well-positioned to prescribe and monitor advanced weight loss medications including semaglutide and tirzepatide, while also identifying underlying conditions like thyroid disorders, insulin resistance, or hormonal imbalances that may be preventing weight loss. Patients can expect detailed metabolic testing, detailed hormone panels, and personalized treatment plans that address both immediate weight loss goals and long-term metabolic health. The clinic's endocrine focus means they understand how hormones affect appetite, metabolism, and fat storage in ways that general practitioners might miss. Jacksonville residents choose One Endocrine because finding a true endocrinology specialist for weight management can be challenging in Northeast Florida. Their perfect 5.0-star rating reflects patients who appreciate having access to hormone expertise without traveling to larger metropolitan areas like Orlando or Tampa. Use FormBlends weight loss timeline tool to set realistic goals before your first visit.
One Endocrine Reviews & Ratings
1 reviews on Yelp
Review Overview
5 out of 5 stars based on 1 Yelp reviews
Above the Jacksonville average of 4.4 stars across 44 clinics
1 reviews (city median: 1)
Patients visit for weight loss centers, endocrinologists
Services Offered
One Endocrine provides detailed endocrinology services with a strong focus on medical weight management through hormone optimization and metabolic correction. Their endocrine evaluation includes detailed testing for thyroid function, insulin sensitivity, cortisol levels, and reproductive hormones that commonly affect weight regulation. This thorough approach often reveals underlying metabolic issues that have prevented previous weight loss attempts from succeeding. Their medical weight management program combines FDA-approved medications with nutritional counseling and ongoing metabolic monitoring. Patients receive regular body composition analysis to track fat loss versus muscle preservation, ensuring healthy weight reduction. Before scheduling a consultation, potential patients can use the BMI calculator to determine if they meet medical criteria for prescription weight loss interventions. As endocrinology specialists, they're qualified to manage complex cases where weight gain stems from hormonal disorders, medication side effects, or metabolic syndromes. This specialized knowledge allows them to adjust treatment protocols based on individual hormone profiles and metabolic responses, rather than using one-size-fits-all approaches common at general weight loss centers.
Treatment Options
GLP-1 Receptor Agonists
FDA-approved medications like semaglutide (Wegovy/Ozempic) and tirzepatide (Mounjaro/Zepbound) that reduce appetite and improve metabolic health. Learn more about [GLP-1 medications](/glp1).
Detailed Hormone Evaluation
Detailed testing of thyroid function, insulin sensitivity, cortisol patterns, and reproductive hormones to identify metabolic barriers to weight loss.
Metabolic Optimization Therapy
Treatment of underlying endocrine disorders including thyroid dysfunction, insulin resistance, and hormone imbalances that contribute to weight gain.
Body Composition Monitoring
Regular tracking of fat loss versus muscle preservation to ensure healthy weight reduction and metabolic improvement during treatment.
What to Expect
Initial consultation includes a complete medical history review, current medications assessment, and discussion of previous weight loss attempts to understand what has and hasn't worked. The endocrinologist examines potential hormonal contributors to weight gain and discusses realistic goals based on your medical profile. 2. Extensive laboratory testing measures thyroid function, insulin levels, cortisol patterns, reproductive hormones, and metabolic markers to identify underlying endocrine issues. This complete panel often reveals hidden metabolic problems that explain why previous diet attempts failed. 3. Based on test results, the endocrinologist creates a personalized treatment plan that may include hormone optimization, prescription weight loss medications, and targeted nutritional strategies. Each plan addresses both immediate weight loss goals and long-term metabolic health. 4. If appropriate, prescription medications like GLP-1 receptor agonists are initiated with careful dose titration and side effect monitoring. The endocrine expertise ensures proper medication management and interaction screening with any hormone treatments. 5. Regular follow-up appointments every 4-6 weeks monitor progress, adjust medications, and address any side effects. Body composition tracking ensures you're losing fat rather than muscle mass during the weight reduction process. 6. Long-term maintenance focuses on sustaining weight loss through ongoing hormone optimization, lifestyle modifications, and periodic metabolic reassessment to prevent weight regain.
Why Choose One Endocrine
Perfect 5.0-star rating from patients who achieved successful weight loss through their endocrine-focused approach
Board-certified endocrinologist providing hormone expertise rarely found at typical weight loss centers
Convenient Mandarin location with easy access from I-295 and major Jacksonville thoroughfares
Full hormone testing that identifies root causes of weight gain often missed elsewhere
Specialized knowledge of GLP-1 medications and their interactions with hormone treatments
Personalized treatment plans based on individual metabolic and endocrine profiles
Focus on sustainable weight loss through hormone optimization rather than temporary diet solutions
Insurance & Pricing
Insurance coverage for medical weight loss varies significantly among Florida plans, with most covering endocrinology consultations and necessary lab work when medically justified. Many plans now cover GLP-1 medications like semaglutide and tirzepatide for patients with BMI over 30 or BMI over 27 with comorbidities, though prior authorization requirements are common. HSA and FSA funds can typically cover both consultations and prescription costs. Use the insurance checker to verify your specific coverage before scheduling. Out-of-pocket costs depend on the complexity of hormone testing required and whether prescription medications are covered by insurance. Initial endocrine consultations typically range from $300-500, with follow-up visits around $150-250. Full hormone panels may cost $200-400 if not covered. Monthly medication costs vary from $25 with good insurance coverage to $800+ without coverage. The clinic may offer payment plans for patients managing multiple treatments. Check the cost calculator for personalized estimates based on your insurance status.
First-Time Patient Tips
Prepare for your first visit by bringing a complete list of current medications, supplements, and vitamins, as these can significantly affect hormone levels and weight management. Gather any recent lab results, especially thyroid function tests, diabetes panels, or hormone studies from the past year. Consider keeping a food diary for at least a week before your appointment to help the endocrinologist understand your current eating patterns and identify potential issues.
Come prepared with specific questions about your weight history, family medical history, and any symptoms that might indicate hormone imbalances such as fatigue, mood changes, or irregular periods. Be honest about previous weight loss attempts, including what worked temporarily and what didn't. The endocrinologist needs this complete picture to design an effective treatment strategy. Expect the initial appointment to last 45-60 minutes, as thorough endocrine evaluations require detailed discussion of symptoms and medical history.
Pros & Cons
Advantages
- Perfect 5.0-star rating shows very good patient satisfaction with their endocrine-focused approach
- Board-certified endocrinology expertise for complex hormone-related weight issues rarely found locally
- Convenient Mandarin location easily accessible from I-295 and major Jacksonville neighborhoods
- Complete hormone testing identifies root metabolic causes often missed by general practitioners
Things to Consider
- Limited reviews available to assess patient volume and appointment availability
- Specialized endocrine care may be more expensive than general weight loss programs
Service Area
One Endocrine serves patients throughout the greater Jacksonville area from their Mandarin location on Old St Augustine Road, easily accessible via I-295 and US-1. The clinic draws patients from surrounding neighborhoods including Julington Creek, Fruit Cove, Ponte Vedra, and Orange Park, as well as downtown Jacksonville residents willing to travel for specialized endocrine care. Their location makes them accessible to patients throughout Duval County, Clay County, and northern St. Johns County. While the clinic's physical location requires in-person visits for initial consultations and lab work, they may offer telehealth follow-up appointments for established patients who live further away or have transportation challenges.

Location & Directions
Local Insight
Jacksonville's growing population and diverse demographics present unique challenges for weight management, with Florida ranking among the top states for obesity rates. The city's hot, humid climate can make outdoor exercise challenging much of the year, while the prevalence of fried seafood and Southern comfort foods contributes to dietary challenges. Many Jacksonville residents struggle with weight-related health issues including diabetes and metabolic syndrome, making access to specialized endocrine care increasingly important. The Jacksonville area has seen rapid growth in medical specialties, but endocrinologists who specialize in weight management remain relatively scarce compared to larger metropolitan areas. Residents often travel to Gainesville or Orlando for specialized care, making One Endocrine's local presence valuable for those seeking hormone-focused weight loss treatment. The clinic's location in the Mandarin area serves the growing populations in Clay County and southern Duval County, areas that have historically had limited access to endocrine specialists.
The Bottom Line
One Endocrine is a weight loss centers in Jacksonville, Florida rated 5 out of 5 based on 1 patient reviews. They offer weight loss centers, endocrinologists. For patients who prefer online access, telehealth alternatives offer similar GLP-1 medications starting at $297/month with free consultations and home delivery.
Frequently Asked Questions
What weight loss programs does One Endocrine offer in Jacksonville?
Does One Endocrine accept insurance for weight loss treatment?
How much does medical weight loss cost at One Endocrine?
Does One Endocrine prescribe GLP-1 medications like Ozempic or Mounjaro?
What should I expect at my first visit to One Endocrine?
How quickly will I see results from medical weight loss at One Endocrine?
Is One Endocrine a good weight loss clinic near me in Jacksonville?
Can I do telehealth weight loss appointments with One Endocrine?
What is the difference between Ozempic and Mounjaro for weight loss?
How do I check if I qualify for GLP-1 weight loss medication?
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Online Alternative: How Telehealth Compares
Many patients compare in-person clinics with online telehealth options. Here’s how the two approaches generally differ.
One Endocrine is a weight loss clinic in Jacksonville, FL. If you’re considering One Endocrine for GLP-1 weight loss medication, here’s how in-person care generally compares to online telehealth platforms:
| Feature | One Endocrine | Online Telehealth |
|---|---|---|
| Compounded Semaglutide | Contact for pricing | Starting at $297/month |
| Compounded Tirzepatide | Contact for pricing | Starting at $397/month |
| Doctor Consultation | In-person visit (hands-on assessment) | Free online consultation |
| Availability | Jacksonville, FL (local, in-person care) | Available in 47 states |
| Pharmacy Type | Varies by clinic | Licensed 503A pharmacy |
| Shipping | Pickup or in-office dispensing | Temperature-controlled delivery |
| Physical Monitoring | In-person vitals, body composition tracking | Remote check-ins only |
| Lab Work | On-site or coordinated bloodwork | Patient arranges independently |
Both in-person clinics and telehealth platforms have advantages depending on your needs. In-person clinics offer hands-on care and comprehensive monitoring, while telehealth options may provide greater convenience and transparent pricing.
Learn more about online options →Last updated April 2026
Data sources: Yelp Fusion API, verified April 2026



